Genetics and Genomics in Medicine

ISBN-10: 0815344805
ISBN-13: 9780815344803
Edition: 2014
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Description: This new textbook from Tom Strachan (with clinical colleagues) explains the science behind the uses of genetics and genomics in medicine today. It is not just about rare inherited and chromosomal disorders, but how genetics affects the whole  More...

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Book details

Copyright year: 2014
Publisher: Taylor & Francis Group
Publication date: 6/10/2014
Binding: Paperback
Pages: 500
Size: 8.25" wide x 10.50" long x 0.75" tall
Weight: 1.782
Language: English

This new textbook from Tom Strachan (with clinical colleagues) explains the science behind the uses of genetics and genomics in medicine today. It is not just about rare inherited and chromosomal disorders, but how genetics affects the whole spectrum of human health and disease. DNA technologies are explained, with emphasis on the modern techniques that have revolutionized the use of genetic information in medicine and are indicating the role of genetics in common diseases. Other new advances, such as the role of RNA and epigenetics are also included. The discussion on genetic approaches to treatment includes pharmacogenomics and the prospects for personalized medicine. Cancer is essentially a genetic disease and is given a dedicated chapter. There are extensive questions and problems for each chapter and clinical disorder boxes throughout.

Tom Strachan is Scientific Director of the Institute of Human Genetics and Professor of Human Molecular Genetics at Newcastle University, UK, and is a Fellow of the Academy of Medical Sciences and a Fellow of the Royal Society of Edinburgh. Tom's early research interests were in multigene family evolution and interlocus sequence exchange, notably in the HLA and 21-hydroxylase gene clusters. While pursuing the latter, he became interested in medical genetics and disorders of development. His most recent research has focused on developmental control of the vertebrate cohesion regulators Nipbl and Mau-2.Andrew Read is Emeritus Professor of Human Genetics at the University of Manchester, UK and a Fellow of the Academy of Medical Sciences. Andrew has been particularly concerned with making the benefits of DNA technology available to people with genetic problems. He established one of the first DNA diagnostic laboratories in the UK over 20 years ago (it is now one of two National Genetics Reference Laboratories), and was founder chairman of the British Society for Human Genetics, the main professional body in this area. His own research is on the molecular pathology of various hereditary syndromes, especially hereditary hearing loss.Drs. Strachan and Read were recipients of the European Society of Human Genetics Education Award.

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