Fundamental Concepts of Bioinformatics

ISBN-10: 0805346333

ISBN-13: 9780805346336

Edition: 2003

List price: $168.00
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Description: In the first bioinformatics primer for undergraduates, the authors focus on fundamentally important algorithms at the core of bioinformatics. Features include end-of-chapter summaries and questions with answers at the back of the text.

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Book details

List price: $168.00
Copyright year: 2003
Publisher: Benjamin-Cummings Publishing Company
Publication date: 9/12/2002
Binding: Hardcover
Pages: 320
Size: 7.25" wide x 9.00" long x 0.75" tall
Weight: 1.430
Language: English

Molecular Biology and Biological Chemistry
The Genetic Material
Gene Structure and Information Content
Protein Structure and Function
The Nature of Chemical Bonds
Molecular Biology Tools
Genomic Information Content
Data Searches and Pairwise Alignments
Dot Plots
Simple Alignments
Gaps
Scoring Matrices
Dynamic Programming: The Needleman and Wunsch Algorithm
Global and Local Alignments
Database Searches
Multiple Sequence Alignments
Substitution Patterns
Patterns of Substitutions within Genes
Estimating Substitution Numbers
Variations in Evolutionary Rates between Genes
Molecular Clocks
Evolution in Organelles
Distance-Based Methods of Phylogenetics
History of Molecular Phylogenetics
Advantages to Molecular Phylogenies
Phylogenetic Trees
Distance Matrix Methods
Maximum Likelihood Approaches
Multiple Sequence Alignments
Character-Based Methods of Phylogenetics
Parsimony
Inferred Ancestral Sequences
Strategies for Faster Searches
Consensus Trees
Tree Confidence
Comparison of Phylogenetic Methods
Molecular Phylogenies
Genomics and Gene Recognition
Prokaryotic Genomes
Prokaryotic Gene Structure
GC Content in Prokaryotic Genomes
Prokaryotic Gene Density
Eukaryotic Genomes
Eukaryotic Gene Structure
Open Reading Frames
GC Content in Eukaryotic Genomes
Gene Expression
Transposition
Repetitive Elements
Eukaryotic Gene Density
Protein and RNA Structure Prediction
Amino Acids
Polypeptide Composition
Secondary Structure
Tertiary and Quaternary Structure
Algorithms for Modeling Protein Folding
Structure Prediction
Predicting RNA Secondary Structures
Proteomics
From Genomes to Proteomes
Protein Classification
Experimental Techniques
Inhibitors and Drug Design
Ligand Screening
X-Ray Crystal Structures
NMR Structures
Empirical Methods and Prediction Techniques
Post-Translational Modification Prediction
A Gentle Introduction to Computer Programming and Data Structures
Enzyme Kinetics
Sample Programs in Perl
Glossary
Solutions to Selected Problems
Index
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