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Molecular Biology and Biological Chemistry | |
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The Genetic Material | |
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Gene Structure and Information Content | |
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Protein Structure and Function | |
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The Nature of Chemical Bonds | |
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Molecular Biology Tools | |
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Genomic Information Content | |
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Data Searches and Pairwise Alignments | |
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Dot Plots | |
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Simple Alignments | |
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Gaps | |
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Scoring Matrices | |
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Dynamic Programming: The Needleman and Wunsch Algorithm | |
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Global and Local Alignments | |
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Database Searches | |
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Multiple Sequence Alignments | |
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Substitution Patterns | |
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Patterns of Substitutions within Genes | |
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Estimating Substitution Numbers | |
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Variations in Evolutionary Rates between Genes | |
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Molecular Clocks | |
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Evolution in Organelles | |
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Distance-Based Methods of Phylogenetics | |
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History of Molecular Phylogenetics | |
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Advantages to Molecular Phylogenies | |
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Phylogenetic Trees | |
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Distance Matrix Methods | |
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Maximum Likelihood Approaches | |
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Multiple Sequence Alignments | |
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Character-Based Methods of Phylogenetics | |
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Parsimony | |
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Inferred Ancestral Sequences | |
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Strategies for Faster Searches | |
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Consensus Trees | |
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Tree Confidence | |
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Comparison of Phylogenetic Methods | |
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Molecular Phylogenies | |
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Genomics and Gene Recognition | |
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Prokaryotic Genomes | |
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Prokaryotic Gene Structure | |
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GC Content in Prokaryotic Genomes | |
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Prokaryotic Gene Density | |
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Eukaryotic Genomes | |
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Eukaryotic Gene Structure | |
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Open Reading Frames | |
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GC Content in Eukaryotic Genomes | |
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Gene Expression | |
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Transposition | |
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Repetitive Elements | |
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Eukaryotic Gene Density | |
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Protein and RNA Structure Prediction | |
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Amino Acids | |
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Polypeptide Composition | |
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Secondary Structure | |
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Tertiary and Quaternary Structure | |
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Algorithms for Modeling Protein Folding | |
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Structure Prediction | |
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Predicting RNA Secondary Structures | |
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Proteomics | |
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From Genomes to Proteomes | |
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Protein Classification | |
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Experimental Techniques | |
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Inhibitors and Drug Design | |
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Ligand Screening | |
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X-Ray Crystal Structures | |
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NMR Structures | |
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Empirical Methods and Prediction Techniques | |
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Post-Translational Modification Prediction | |
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A Gentle Introduction to Computer Programming and Data Structures | |
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Enzyme Kinetics | |
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Sample Programs in Perl | |
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Glossary | |
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Solutions to Selected Problems | |
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Index | |