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Basic Clinical Pharmacokinetics

ISBN-10: 0781779030
ISBN-13: 9780781779036
Edition: 5th 2010 (Revised)
List price: $57.00 Buy it from $27.11
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Description: Basic Clinical Pharmacokinetics was designed to simplify pharmacokinetics to help busy practitioners understand and visualize basic principles. An easy-to-read, case-study format has made the text a favorite among clinical professors, students, and  More...

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Book details

List price: $57.00
Edition: 5th
Copyright year: 2010
Publisher: Lippincott Williams & Wilkins
Publication date: 10/5/2009
Binding: Paperback
Pages: 560
Size: 6.00" wide x 9.00" long x 1.00" tall
Weight: 1.760

Basic Clinical Pharmacokinetics was designed to simplify pharmacokinetics to help busy practitioners understand and visualize basic principles. An easy-to-read, case-study format has made the text a favorite among clinical professors, students, and practitioners. The text provides an introduction to the principles of monitoring drug therapy for those involved in the interpretation of drug levels in a patient care setting. Part One provides a basic review of pharmacokinetic principles. Extensive explanations, graphic illustrations, and detailed algorithms teach the principles of bioavailability, volume of distribution, clearance, elimination rate constant, and half-life. Part Two explains the clinical applications of these principles. Solutions to problems commonly encountered in the practice setting are discussed for specific drugs. Appendices provide commonly used equations and a glossary of pharmacokinetic terms and abbreviations. New to this edition are chapters on tricyclic antidepressants and cyclosporine, an expanded chapter on dialysis, and updated information on choosing equations and interpreting plasma drug concentrations.

Basic Principles
Bioavailability
Administrative Rate
Desired Plasma Concentration
Volume of Distribution
Clearance
Elimination Rate Constant(K) and Half-Life (t1/2)
Maximum and Minimum Plasma Concentrations
Selecting the Appropriate Equation
Interpretation of Plasma Drug Concentrations
Creatinine Clearance
Dialysis of Drugs
Drug Monographs
Aminoglycoside Antibiotics
Carbamazepine
Digoxin
Ethosuximide
Immunosuppressants: Cyclosporine, Tacrolimus and Sirolimus
Lidocaine
Lithium
Methotrexate (MTX)
Phenobarbital
Phenytoin
Theophylline
Valproic Acid
Vancomycin

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