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| Preface | |
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| Acknowledgments | |
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| Overview | |
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| Synopsis | |
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| Concerns in Medicine | |
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| Host-Parasite Equilibrium | |
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| Development of the Acquired Immune System | |
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| Clonal Selection Theory | |
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| Antigens | |
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| Definitions | |
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| Factors Determining Antigenicity | |
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| Examples of Antigens | |
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| Innate Immunity | |
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| Fundamental Characteristics | |
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| Defensive Mechanisms | |
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| Acute Phase Response (APR) | |
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| Pathogen Recognition Systems | |
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| Antibodies | |
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| General Properties | |
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| IgG | |
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| IgM | |
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| IgA | |
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| IgE | |
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| IgD | |
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| Immunogenetics | |
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| Genetic Control of Immunoglobulin Chain Synthesis | |
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| Genetic Control of Human Leukocyte Antigens (HLAs) | |
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| Genetic Control of the T-Cell Antigenic Receptor (TCR) | |
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| Immunologic Assays | |
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| Overview | |
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| Protection Tests | |
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| Agglutination Tests | |
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| Precipitation Reactions | |
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| Complement Fixation | |
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| Fluorescent Antibody | |
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| Western Blot | |
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| Cell Counting and Flow Cytometry | |
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| Reverse Transcription Polymerase Chain Reaction (RT-PCR) | |
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| DNA Microarrays | |
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| The Immune Response | |
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| Humoral Immunity | |
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| Cell-Mediated Immunity (CMI) | |
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| Signal Transduction in Immune Cells | |
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| Effective Immune Responses Require Communication Between a Wide Range of Cell Types | |
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| Receptor Architecture and Fundamental Characteristics | |
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| Signaling Molecules | |
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| Pathways | |
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| Inflammation | |
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| Introduction | |
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| Inflammation Process | |
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| Kinetics | |
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| Mediators of Inflammation | |
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| Hypersensitivity Diseases | |
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| Overview | |
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| Anaphylaxis (Type I) Reactions | |
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| Cell Surface Antigen-Antibody (Ag-Ab) Cytotoxicity (Type II) Reactions | |
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| Antigen-Antibody (Ag-Ab) Complex (Type III) Reactions | |
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| Delayed-Type Hypersensitivity (Type IV) Reactions | |
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| Immunodeficiency Diseases | |
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| Overview | |
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| Developmental Immunodeficiency Disorders | |
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| Acquired Immunodeficiency Syndrome (AIDS) | |
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| Cytokine and Chemokine Deficiencies | |
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| Senescence (Aging) of the Immune Response | |
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| Autoimmune Disorders | |
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| Overview | |
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| Immunoregulation Breakdown | |
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| Systemic Autoimmune Disorders | |
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| Organ-Specific Autoimmune Disorders | |
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| Immunologic Aspects of Transplantation | |
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| Histocompatibility | |
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| Complications of Organ Transplantation | |
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| Immunosuppression | |
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| Cancer Immunology | |
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| Definition | |
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| Oncogenes | |
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| Cancer and the Immune System | |
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| Cancer Immunotherapy | |
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| Immunization | |
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| Overview | |
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| Specific Vaccines | |
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| Adjuvants | |
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| Study Questions and Answers | |