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| Introduction to Pathophysiology | |
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| Cell and Tissue Function | |
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| Cell Structure and Function | |
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| Functional Components of the Cell | |
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| Cell Metabolism and Energy Sources | |
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| Cell Membrane Transport, Signal Transduction, and Generation of Membrane Potentials | |
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| Body Tissues | |
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| Cellular Responses to Stress, Injury, and Aging | |
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| Cellular Responses to Stress | |
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| Cell Injury and Death | |
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| Cellular Aging | |
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| Genetic Control of Cell Function and Inheritance | |
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| Genetic Control of Cell Function | |
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| Chromosomes | |
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| Patterns of Inheritance | |
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| Gene Technology | |
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| Genetic and Congenital Disorders | |
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| Genetic and Chromosomal Disorders | |
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| Disorders Due to Environmental Influences | |
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| Prenatal Diagnosis | |
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| Neoplasia: A Disorder of Cell Proliferation and Differentiation | |
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| Concepts of Cell Growth | |
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| Benign and Malignant Neoplasms | |
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| Etiology of Cancer | |
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| Clinical Manifestations | |
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| Diagnosis and Treatment | |
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| Childhood Cancers | |
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| Integrative Body Functions | |
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| Disorders of Fluid, Electrolyte, and Acid-Base Balance | |
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| Composition and Compartmental Distribution of Body Fluids | |
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| Sodium and Water Balance | |
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| Potassium Balance | |
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| Calcium and Magnesium Balance | |
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| Acid-Base Balance | |
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| Stress and Adaptation | |
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| Stress and Adaptation | |
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| Disorders of the Stress Response | |
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| Alterations in Body Nutrition | |
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| Regulation of Food Intake and Energy Metabolism | |
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| Overnutrition and Obesity | |
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| Undernutrition | |
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| Hematopoietic Function | |
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| Disorders of White Blood Cells and Lymphoid Tissues | |
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| Hematopoietic and Lymphoid Tissue | |
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| Non-neoplastic Disorders of White Blood Cells | |
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| Neoplastic Disorders of Hematopoietic and Lymphoid Origin | |
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| Alterations in Hemostasis | |
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| Mechanisms of Hemostasis | |
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| Hypercoagulability States | |
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| Bleeding Disorders | |
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| The Red Blood Cell and Alterations in Oxygen Transport | |
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| The Red Blood Cell | |
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| Anemia | |
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| Polycythemia | |
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| Age-Related Changes in Red Blood Cells | |
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| Infection, Inflammation, and Immunity | |
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| Mechanisms of Infectious Disease | |
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| Infectious Diseases | |
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| Mechanisms of Infection | |
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| Diagnosis and Treatment of Infectious Diseases | |
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| Bioterrorism and Emerging Global Infectious Diseases | |
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| The Immune Response | |
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| The Immune System | |
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| Effector Responses of the Immune System | |
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| Developmental Aspects of the Immune System | |
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| Inflammation, Tissue Repair, and Fever | |
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| The Inflammatory Response | |
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| Tissue Repair and Wound Healing | |
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| Temperature Regulation and Fever | |
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| Alterations in the Immune Response | |
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| Hypersensitivity Disorders | |
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| Autoimmune Disease | |
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| Transplantation Immunopathology | |
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| Immunodeficiency Disorders | |
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| Circulatory Function | |
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| Control of Cardiovascular Function | |
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| Organization of the Circulatory System | |
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| Principles of Blood Flow | |
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| The Heart as a Pump | |
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| Blood Vessels and the Peripheral Circulation | |
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| Autonomic Nervous System Control of Circulatory Function | |
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| Disorders of Blood Flow and Blood Pressure | |
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| Blood Vessel Structure and Function | |
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| Disorders of the Arterial Circulation | |
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| Disorders of Arterial Blood Pressure | |
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| Disorders of the Venous Circulation | |
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| Disorders of Cardiac Function | |
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| Disorders of the Pericardium | |
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| Coronary Heart Disease | |
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| Myocardial and Endocardial Diseases | |
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| Valvular Heart Disease | |
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| Heart Disease in Infants and Children | |
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| Heart Failure and Circulatory Shock | |
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| Heart Failure | |
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| Circulatory Failure (Shock) | |
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| Circulatory Failure in Children and the Elderly | |
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| Respiratory Function | |
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| Control of Respiratory Function | |
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| Structural Organization of the Respiratory System | |
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| Exchange of Gases Between the Atmosphere and the Lungs | |
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| Exchange and Transport of Gases | |
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| Control of Breathing | |
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| Respiratory Tract Infections, Neoplasia, and Childhood Disorders | |
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| Respiratory Tract Infections | |
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| Cancer of the Lung | |
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| Respiratory Disorders in Children | |
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| Disorders of Ventilation and Gas Exchange | |
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| Disorders of Lung Inflation | |
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| Obstructive Airway Disorders | |
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| Chronic Interstitial Lung Diseases | |
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| Pulmonary Vascular Disorders | |
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| Respiratory Failure | |
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| Kidney and Urinary Tract Function | |
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| Control of Kidney Function | |
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| Kidney Structure and Function | |
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| Tests of Renal Function | |
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| Disorders of Renal Function | |
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| Congenital Disorders of the Kidneys | |
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| Obstructive Disorders | |
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| Urinary Tract Infections | |
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| Disorders of Glomerular Function | |
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| Tubulointerstitial Disorders | |
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| Neoplasms | |
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| Renal Failure | |
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| Acute Renal Failure | |
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| Chronic Renal Failure | |
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| Renal Failure in Children and Elderly Persons | |
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| Disorders of Urine Elimination | |
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| Control of Urine Elimination | |
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| Alterations in Bladder Function | |
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| Cancer of the Bladder | |
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| Gastrointestinal and Hepatobiliary Function | |
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| Structure and Function of the Gastrointestinal System | |
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| Structure and Organization of the Gastrointestinal Tract | |
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| Innervation and Motility | |
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| Hormonal and Secretory Function | |
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| Digestion and Absorption | |
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| Anorexia, Nausea, and Vomiting | |
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| Disorders of Gastrointestinal Function | |
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| Disorders of the Esophagus | |
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| Disorders of the Stomach | |
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| Disorders of the Small and Large Intestines | |
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| Disorders of Hepatobiliary and Exocrine Pancreas Function | |
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| The Liver and Hepatobiliary System | |
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| Disorders of Hepatic and Biliary Function | |
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| Disorders of the Gallbladder and Exocrine Pancreas | |
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| Endocrine System | |
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| Organization and Control of the Endocrine System | |
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| The Endocrine System | |
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| Disorders of Endocrine Function | |
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| General Aspects of Altered Endocrine Function | |
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| Pituitary and Growth Disorders | |
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| Thyroid Disorders | |
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| Disorders of Adrenal Cortical Function | |
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| Diabetes Mellitus and the Metabolic Syndrome | |
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| Hormonal Control of Glucose, Fat, and Protein Metabolism | |
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| Diabetes Mellitus | |
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| Nervous System | |
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| Organization and Control of Neural Function | |
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| Nervous Tissue Cells | |
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| Nerve Cell Communication | |
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| Developmental Organization of the Nervous System | |
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| Spinal Cord and Brain | |
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| The Autonomic Nervous System | |
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| Disorders of Somatosensory Function and Pain | |
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| Organization and Control of Somatosensory Function | |
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| Pain | |
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| Alterations in Pain Sensitivity and Special Types of Pain | |
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| Headache | |
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| Pain in children and Older Adults | |
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| Disorders of Neuromuscular Function | |
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| Organization and Control of Motor Function | |
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| Skeletal Muscle, Neuromuscular Junction, and Peripheral Nerve Disorders | |
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| Basal Ganglia and Cerebellum Disorders | |
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| Upper Motor Neuron Disorders | |
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| Disorders of Brain Function | |
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| Mechanisms and Manifestations of Brain Injury | |
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| Cerebrovascular Disease | |
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| Infections and Brain Tumors | |
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| Seizure Disorders | |
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| Dementias | |
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| Disorders of Special Sensory Function: Vision, Hearing, and Vestibular Function | |
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| The Eye and Disorders of Vision | |
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| The Ear and Disorders of Auditory Function | |
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| Disorders of Vestibular Function | |
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| Genitourinary and Reproductive Function | |
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| Disorders of the Male Genitourinary System | |
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| Physiologic Basis of Male Reproductive Function | |
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| Disorders of the Penis, the Scrotum and Testes, and the Prostate | |
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| Disorders in Childhood and Aging Changes | |
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| Disorders of the Female Genitourinary System | |
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| Structure and Function of the Female Reproductive System | |
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| Disorders of the Female Reproductive Organs | |
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| Menstrual Disorders | |
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| Disorders of the Breast | |
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| Sexually Transmitted Diseases | |
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| Infections of the External Genitalia | |
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| Vaginal Infections | |
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| Urogenital-Systemic Infections | |
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| Musculoskeletal Function | |
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| Structure and Function of the Skeletal System | |
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| Characteristics of Skeletal Tissue | |
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| Skeletal Structures | |
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| Disorders of the Skeletal System: Trauma, Infection, and Childhood Disorders | |
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| Injury and Trauma of Musculoskeletal Structures | |
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| Infections and Osteonecrosis | |
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| Neoplasms | |
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| Skeletal Disorders in Children | |
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| Disorders of the Skeletal System: Metabolic and Rheumatic Disorders | |
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| Metabolic Bone Disease | |
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| Rheumatic Disorders | |
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| Rheumatic Diseases in Children and the Elderly | |
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| Integumentary Function | |
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| Structure and Function of the Skin | |
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| Structure of the Skin | |
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| Manifestations of Skin Disorders | |
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| Disorders of the Skin | |
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| Primary Disorders of the Skin | |
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| Ultraviolet Radiation, Thermal, and Pressure Injury | |
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| Nevi and Skin Cancers | |
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| Age-Related Skin Manifestations | |
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| Glossary | |
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| Laboratory Values | |
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| Index | |