Introduction to Pharmacokinetics and Pharmacodynamics The Quantitative Basis of Drug Therapy

ISBN-10: 0781751497
ISBN-13: 9780781751490
Edition: 2006
List price: $82.99 Buy it from $26.08
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Description: "This unique, easy-to-read primer on pharmacokinetics and pharmacodynamics helps students and practitioners understand the basic principles upon which qualitative decisions in drug therapy are based. Written by distinguished experts in the field, it  More...

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Book details

List price: $82.99
Copyright year: 2006
Publisher: Lippincott Williams & Wilkins
Publication date: 2/22/2006
Binding: Paperback
Pages: 336
Size: 7.50" wide x 10.25" long x 0.75" tall
Weight: 1.144
Language: English

"This unique, easy-to-read primer on pharmacokinetics and pharmacodynamics helps students and practitioners understand the basic principles upon which qualitative decisions in drug therapy are based. Written by distinguished experts in the field, it is the first clinically oriented, introductory-level textbook of its kind to pursue an integrated approach to drug exposure within the body and drug response."--BOOK JACKET.

Opening comments
Basic considerations
Input-exposure relationships
Exposure-response relationships
Exposure and response after a single dose
Membranes : a determining factor
Disposition following intravenous bolus
Extravascular dose and systemic absorption
Response following a single dose
Therapeutic regimens
Therapeutic window
Constant-rate regimens
Multiple-dose regimens
Individualization
Variability
Initiating and managing therapy
Nonproprietary and brand names of drugs in text and illustrations
Assessment of AUC
Ionization and the pH partition hypothesis
Amount of drug in the body on accumulation to plateau

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