Essentials of Immunology and Serology

ISBN-10: 076681064X

ISBN-13: 9780766810648

Edition: 2002

List price: $156.95 Buy it from $2.00
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Description:

Anyone pursuing a career in the medical laboratory will want to have this comprehensive, yet straightforward, text. Essentials of Immunology and Serology doesn't just study the components of the immune system, it covers the way in which these components combine to generate the immune response and how these responses relate to infectious diseases, autoimmunity, tumors, hypersensitivity and transplantation. Covers the application and interpretation of a wide array of medical test kits, unlike other texts that focus only on one outdated procedure. An ideal resource for users pursuing medical lab careers that meets the immunology guidelines of the American Society of Clinical Pathologists. Key Words: immonology, serology, laboratory, immune system, autoimmunity, clinical pathology,
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Book details

List price: $156.95
Copyright year: 2002
Publisher: Delmar Cengage Learning
Publication date: 3/6/2002
Binding: Hardcover
Pages: 448
Size: 8.25" wide x 10.50" long x 0.75" tall
Weight: 2.442
Language: English

List of Cases
List of Laboratory Techniques
Preface
About the Author
Functions of the Immune System and Immunity
An Overview of the Immune System
Historical Perspective
An Introduction to the Immune System
Overview of Innate and Adaptive Immune Integration
Immunodeficiencies
Antigens and Antigen Recognition
Antigens
Activators of Lymphocytes
Antigen Recognition
Antibodies
Antibodies
Antigen Antibody Interactions
Classification of Antibodies
Properties and Biological Functions of Antibody Isotypes
Quantitation of Serum Antibodies
Monoclonal Antibodies
Cells and Tissues of Innate Immunity
Lymphoid Tissues
Cells of Innate Immunity
Assessing Dysfunction in Phagocytes and Natural Killer Cells
Separation of Cell Populations
B cells
B cells
B cell Maturation
Naive B cell Activation Following Antigen Encounter
Secondary Immune Responses
B cell Responses to T-Independent Antigens
B cell Responses to Polyclonal Activators
B cell Enumeration and B cell Function
The Major Histocompatibility Complex, Antigen Processing, and Antigen Presentation
Recognition of Non-Self
Major Histocompatibility Complex
MHC Genes and Disease
Transplantation
Antigen Processing and Antigen Presentation
T cells
T cells
General Features of T cell Receptors
T cell Maturation
CD4+ T cells Encounter Antigen
CD8+ T cells Encounter Antigen
Memory T cells
Enumeration of T cells
Approaches for the Isolation of T cells
Assessing T cell Function
Complement
Complement
Classical Pathway of Complement
Alternative Pathway of Complement
Regulation of Complement
Complement Receptors
Biological Activities of Complement
Complement Deficiencies and Disease
Evaluating Complement Pathways
Orchestration of Host Defenses in Response to Infection
Orchestration of Host Defenses in Response to Infection
Infectious Agents Outside Cells: Extracellular Microbes
Microbes That Thrive in the Phagosomes
Microbes Present in the Cell Cytosol
Laboratory Techniques
Instrumentation
Instrumentation for Measurement of Antigen-Antibody Interactions
Instrumentation for Measuring Color Intensity
Instrumentation for Measuring Chemiluminescence
Instrumentation for Measuring Fluorescence
Instrumentation for Detecting Radioactivity
Instrumentation for Detecting Non-labeled Immune Complexes
Indicator Labels
Indicator-labeled Immunoassays
Methods of Coupling Indicator Labels to Antigens or Antibodies
Standard Curves in Immunoassays
Principles of Immunoassays That Use Indicator Labels
Indicator-labeled Immunoassays: Nomenclature
Precipitation
Antigen and Antibody Interactions
The Precipitin Curve
Immunodiffusion
Immunodiffusion Techniques
Single Immunodiffusion Techniques
Double Immunodiffusion Techniques
Electrophoresis
Electrophoresis
Factors That Influence the Rate of Protein Migration
Non Soluble Support Mediums
Zone Electrophoresis
Two-Stage Approach to Immunoelectrophoresis
One-Stage Approach to Immunoelectrophoresis
Polyacrylamide Gel Electrophoresis
Agglutination
Agglutination
Principles of Agglutination
Agglutination Techniques
Types of Agglutination Reactions
Antiglobulins Tests
Applications of the Agglutination/Hemagglutination Reaction
Molecular Diagnostic Technology
Molecular Diagnostic Technology
Nucleic Acids
Molecular Biology Tools
Amplification of Nucleic Acids
Signal Amplification Assays
Capture and Detection Techniques
Molecular Blotting Techniques
Detecting Genetic Mutations in Clinical Laboratories
Diseases and Disorders
Bacterial Infections in Sexually Transmitted Diseases
Venereal Syphilis: Treponema pallidum
Laboratory Diagnosis
Gonorrhoea: Neisseria gonorrhoeae
Laboratory Diagnosis
Genital Tract Infection: Chlamydia trachomatis
Laboratory Diagnosis
Upper Respiratory Tract Bacterial Infections
Atypical Pneumonia: Mycoplasma pneumoniae
Streptococcal Infections: Streptoccaceae
Whooping Cough: Bordetella pertussis
Bacterial Infections: Tick Borne, Enteric, and Zoonotic
Lyme Disease: Borrelia burgdorferi
Rocky Mountain Spotted Fever: Rickettsia rickettsii
Leptospirosis: Leptospira interrogans
Salmonellosis and Typhoid Fever: Salmonella species
Hepatitis
The Causative Agents of Hepatitis
Clinical Manifestations/Pathology
Immunology of Hepatitis Infections
Immunization
Laboratory Diagnosis
Measles, Mumps, Rubella, and Varicella
Measles
Mumps
Rubella
Varicella
Viruses III
Adenovirus
Cytomegalovirus
Epstein Barr Virus
Influenza Virus
Polio
Retroviral Infections
General Features of Retroviruses
HIV
Human T cell Leukemia Virus
Fungal Infections
Aspergillus fumigatus
Candida albicans
Cryptococcus neoformans
Parasitic Infections
Amebic Infections
Echinococcosis: Echinococcus granulosus
Malaria
Toxoplasma gondii
Autoimmune Disorders
Autoimmunity
Diabetes Mellitus
Rheumatoid Arthritis
Systemic Lupus Erythematosus
Graves' Disease
Hashimoto's Thyroiditis
Pernicious Anemia
Tumor Immunology
Tumor Immunology
Tumor Antigens
Immunological Responses to Tumors
Mechanisms by Which Tumors Evade the Immune System
Myeloid and Lymphoid Neoplasms
Immunodeficiency Disorders
Primary Immunodeficiency Disorders
Secondary Immunodeficiency Disorders
Laboratory Tests
Hypersensitivity
Hypersensitivity
Type I Hypersensitivity Reactions
Type II Hypersensitivity Reactions
Type III Hypersensitivity Reactions
Type IV Hypersensitivity Reactions
Laboratory Testing for IgE Antibodies
Laboratory Biosafety
DNA and RNA Viruses
Textbook References
Immunology References
Vaccine References
Laboratory Techniques References
List of Journals
List of Web Sites
Conferences
Glossary
Index
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