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Essential Evidence-Based Medicine

ISBN-10: 0521712416
ISBN-13: 9780521712415
Edition: 2nd 2010 (Revised)
Authors: Dan Mayer
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Book details

List price: $88.95
Edition: 2nd
Copyright year: 2010
Publisher: Cambridge University Press
Publication date: 11/19/2009
Binding: Mixed Media
Pages: 445
Size: 7.50" wide x 9.50" long x 1.25" tall
Weight: 2.970
Language: English

Dan Mayer is Professor of Emergency Medicine, Albany Medical College, New York, USA.

List of contributors
Preface
Foreword
Acknowledgments
A brief history of medicine and statistics
What is evidence-based medicine?
Causation
The medical literature: an overview
Sarching the medical literature
Study design and strength of evidence
Instruments and measurements: precision and validity
Sources of bias
Review of basic statistics
Hypothesis testing
Type I errors and number needed to treat
Negative studies and Type II errors
Risk assessment
Adjustment and multivariate analysis
Randomized clinical trials
Scientific integrity and the responsible conduct of research
Applicability and strength of evidence
Communicating evidence to patients
Critical appraisal of qualitative research studies
An overview of decision making in medicine
Sources of error in the clinical encounter
The use of diagnostic tests
Utility and characteristics of diagnostic tests: likelihood ratios, sensitivity, and specificity
Bayes' theorem, predictive values, post-test probabilities, and interval likelihood ratios
Comparing tests and using ROC curves
Incremental gain and the threshold approach to diagnostic testing
Sources of bias and critical appraisal of studies of diagnostic tests
Screening tests
Practice guidelines and clinical prediction rules
Decision analysis and quantifying patient values
Cost-effectiveness analysis
Survival analysis and studies of prognosis
Meta-analysis and systematic reviews
Levels of evidence and grades of recommendations
Overview of critical appraisal
Commonly used statistical tests
Formulas
Proof of Bayes' theorem
Using balance sheets to calculate thresholds
Glossary
Bibliography
Index

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