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Fed-Batch Cultures: Principles and Applications of Semi-batch Bioreactors

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ISBN-10: 0521513367

ISBN-13: 9780521513364

Edition: 2013

Authors: Henry C. Lim, Hwa Sung Shin

List price: $135.00
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Description:

Many, if not most, industrially important fermentation and bioreactor operations are carried out in fed-batch mode, producing a wide variety of products. In spite of this, there is no single book that deals with fed-batch operations. This is the first book that puts together all the necessary background material regarding the "what, why, and how" of optimal and sub-optimal fed-batch operations. Numerous examples are provided to illustrate the application of optimal fed-batch cultures. This unique book, by world experts with decades of research and industrial experience, is a must for researchers and industrial practitioners of fed-batch processes (modeling, control, and optimization) in…    
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Book details

List price: $135.00
Copyright year: 2013
Publisher: Cambridge Univ Pr
Binding: Cloth Text 
Pages: 470
Size: 7.25" wide x 10.25" long x 1.25" tall
Weight: 2.178
Language: English

Introduction to fed-batch bioreactors
Idealised reactors and fed-batch reactors
Maximisation of reaction rates and fed-batch operation
Phenomena that favour fed-batch operations
Classification and characteristics of fed-batch cultures
Models based on mass balance equations
Non-equation-based models
Experimental determination of specific rates
Optimization via Pontryagin's maximum principle
Computational techniques
Optimization of single and multiple isothermal reactions
Optimization of fed-batch cultures for cell mass production
Optimization of fed-batch cultures for metabolites
Simple, intuitive adaptive optimization
Measurements, estimation and control
Feasibility assessment and implementable feed rates