Fundamentals of Contemporary Mass Spectrometry

ISBN-10: 0471682292
ISBN-13: 9780471682295
Edition: 2007
List price: $160.00 Buy it from $87.29
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Description: Fundamentals of Contemporary Mass Spectrometry deftly explains mass spectrometry instrumentation and its application to analysis and identification of organic compounds, biological material, and inorganic compounds, as well as applications to  More...

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Book details

List price: $160.00
Copyright year: 2007
Publisher: John Wiley & Sons, Incorporated
Publication date: 4/20/2007
Binding: Hardcover
Pages: 608
Size: 6.50" wide x 9.50" long x 1.25" tall
Weight: 1.232
Language: English

Fundamentals of Contemporary Mass Spectrometry deftly explains mass spectrometry instrumentation and its application to analysis and identification of organic compounds, biological material, and inorganic compounds, as well as applications to quantitative analysis. The book is ideal for use as a textbook for graduate courses and is also a great reference for newcomers to mass spectrometry.

Instrumentation
Basics of Mass Spectrometry
A Brief History of Mass Spectrometry
Unique Features of Mass Spectrometry
Basic Principles of Mass Spectrometry
Anatomy of a Mass Spectrum
Atomic and Molecular Masses
Mass-to-charge Ratio
General Applications
Overview of the Chapter
Excercises
References
Modes of Ionization
Why Ionization is Required?
General Construction of the Ion Source
Gas-Phase Ionization Techniques
Electron Ionization
Chemical Ionization
Charge-exchange Chemical Ionization
Negative-Ion Chemical Ionization
Photoionization
Field Ioniztion
Metastable Atom Bombardment Ionization
Condensed-phase Ionization Techniques: Ionization of
Solid-State Samples
Field Desorption
Plasma Desorption Ionization
Secondary-ion Mass Spectrometry
Fast Atom Bombardment
Laser Desorption/Ionization
Matrix-Assisted Laser Desorption/Ionization
Analysis of Low Molecular Mass Compounds
Atmospheric Pressure
Surface-enhanced Laser Desorption/Ionization
Condensed-phase Ionization Techniques: Ionization of Liquid-State Samples
Thermospray Ionization
Atmospheric Pressure Chemical Ionization
Atmospheric Pressure Photoionization
Electrospray Ionization
Mechanism of Electrospray Ionization
Sample Consideration
Nanoelectrospray Ionization
Desorption Electrospray Ionization
DART Ion Source
OVerview of the Chapter
Exercises
Additional Reading
References
Mass Analysis and Ion Detection
Mass Resolution
Kinetic Energy of Ions
Mass Analyzers
Magnetic Sector Mass Spectrometers
Working Principle of a Magnetic Analyzer
Working Principle of an Electrostatic Analyzer
Working Principle of Double-Focusing Magnetic Sector Mass Spectrometers
Performance Characteristics
Quadrupole Mass Spcetrometers
Working Principle
Performance Characteristics
RF-only quadrupole
Time-of-Flight Mass Spectrometers
Working Principle
Delayed Extraction of Ions
Reflectron TOF Instrument
Orthogonal Acceleration TOF Mass Spectrometer
Performance Characteristics
Quadrupole Ion Trap Mass Spectrometers
Working Principle
Operational Modes
Performance Characteristics
Linear Ion Trap Mass Spectrometers
Rectilinear Ion Trap
Fourier-Transform Ion Cyclotron Resonance Mass Spectrometers
Working Principle
Performance Characteristics
Orbitrap Mass Analyzer
Ion Mobility Mass Spectrometers
Detectors
Faraday Cup Detector
Electron Multipliers
Photomultiplier detectors
Post-acceleration Detectors
Low-temperature Calorimetric Detectors for High Mass Ions
Focal-plane Detectors
Overview of the Chapter
Excercises
Additional Reading
References
Tandem Mass Spectrometry
Basic Principles of Tandem Mass Spectrometry
Types of Scan Functions
Ion Activation and Dissociation
Collision-induced Dissociation
Surface-induced Dissociation
Absorption of Electromagnetic Radiations
Electron-capture Dissociation
Reactions in Tandem Mass Spectrometry
Tandem Mass Spectrometry Instrumentation
Magnetic Sector Tandem Mass Spectrometers
Tandem Mass Spectrometry with Multiple Quadrupole Devices
Tandem Mass Spectrometry with Time-of-Flight Instruments
Tandem Mass Spectrometry with a Quadrupole Ion Trap Mass Spectrometer
Tandem Mass Spectrometry with an FT-ICR Mass Spectrometer
Tandem Mass Spectrometry with Hybrid Instruments
Overview of the Chapter
Excercises
Additional Reading
References
Hyphenated Separation Techniques
Benefits of the Coupling of Separation Devices with Mas

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