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Bioinstrumentation

ISBN-10: 0471263273
ISBN-13: 9780471263272
Edition: 2004
List price: $217.95 Buy it from $19.75
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Description: Addresses measurements in new fields such as cellular and molecular biology. Equips readers with the necessary background in electric circuits. Statistical coverage shows how to determine trial sizes.

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Book details

List price: $217.95
Copyright year: 2004
Publisher: John Wiley & Sons, Incorporated
Publication date: 8/18/2003
Binding: Hardcover
Pages: 400
Size: 8.00" wide x 9.75" long x 1.25" tall
Weight: 6.996
Language: English

Addresses measurements in new fields such as cellular and molecular biology. Equips readers with the necessary background in electric circuits. Statistical coverage shows how to determine trial sizes.

A pioneer in the biomedical engineering field, John G. Webster is Professor Emeritus at the University of Wisconsin.

Preface
Measurement Systems
Studying Biomedical Engineering
Scales of Biological Organization
Fields of Biomedical Engineering
Fields of Biological Science
Workplace Environments for Biomedical Engineers
The Need for Bioinstrumentation
The Scientific Method
Clinical diagnoses
Feedback in Measurement Systems
Instrumentation
Measurands
Sensors
System Characteristics
Outputs
Panels and Series
Errors in Measurements
Sources of Error
Accuracy and Precision
Calibration
Statistics
Distributions
Statistical Estimations
Hypothesis Testing
Lifelong Learning
Problems
References
Basic Concepts of Electronics
Electronic Components and Circuit Analysis
Current
Voltage and Potential
Resistors and Ohm's Law
Basic Circuit Analysis
Attenuators
Common Electrical Instruments
Capacitors
Inductors
First-Order Systems
Frequency
Series and Parallel Impedances
Electrical Safety
Amplifiers
Basic Op Amp
Ideal Op Amp
Inverter
Noninverting Amplifier
Differential Amplifiers
Comparators
Frequency Response
Filters
Input-Output Relationship of Filters
Low-pass Filter
High-Pass Filter
Other Filters
Timers
Analog-to-Digital (ADC) and Digital-to-Analog (DAC) Conversion
Number Systems
Digital-to-Analog Converters (DAC)
Analog-to-Digital Converters (ADC)
Digital Signal Processing
Digital Signals
Sampling Theorem
Microcomputers
Structure of a Microcomputer
Microprocessor-Based Systems
Software and Programming Languages
Operating System
Programming Languages
Algorithms
Database systems
Display Devices
Recording Devices
Problems
References
Analysis of Molecules in Clinical Medicine
Spectrophotometry
Components
Theory
Calibration
Clinical Laboratory Tests
Microdialysis
Oxygen Saturation
Bilirubin
Lactate
Creatinine
Urea
Glucose
Glucose Oxidase Method
Hexokinase method
Amperometric Biosensors for Oxygen and Glucose
Oxygen (PO[subscript 2])
Glucose
Ion-selective Electrodes for pH and CO[subscript 2]
Flame Photometry
Lithium
Sodium and Potassium
Mass Spectrometry
Sample Inlet
Ion Source
Mass Analyzer
Detector
Carbon Dioxide Concentration Measurement by Infrared Transmission Spectroscopy
Nitrogen by Emission Spectrometry
Drugs by Fluorometry and Chromatography
Fluorometry
Chromatography
Gas Chromatography
Liquid Chromatography
Ion Exchange Chromatography
Electrophoresis
Components of an Electrophoretic System
Electrophoretic Mobility
DNA Sequencing
Problems
References
Surface Characterization in Biomaterials and Tissue Engineering
Molecules and Biomaterials
Integrated Approach
Types of Biomaterials
Polymers
Molecules and Tissue Engineering
Tissue Engineering
Cellular Composites
Surface Analysis
Topography
Chemical Composition
Polymer-water Interface
Protein Adsorption
Protein Molecule
Protein Adsorption Fundamentals
Protein Adsorption Measurements
Molecular Size
Problems
References
Hematology
Blood Components and Processing
Components of Blood
Basic Techniques
Blood Collection
Centrifugal Method
Red Blood Cells
Factors Affecting Red Blood Cell Count
Hematocrit
Hemoglobin
Red Blood Cell Indices
Red Blood Cell Count
Hemoglobin
Reticulocyte Count
Sickle Cell Test
White Blood Cells
Differential White Blood Cell Counts
Platelets
Phase Hemocytometer
Complete Blood Count
Problems
References
Cellular Measurements in Biomaterials and Tissue Engineering
Cell Measurement Overview
What Is a Cell?
Fixed Versus Live Cells
Light Microscopy
Resolution Versus Magnification
Light Microscope Modes
Electronic Microscopy
Cellular Markers
Confocal Laser Scanning Microscopy
Two-Photon Excitation Microscopy
Image Processing
Cell Orientation
Orientation Chamber
Video enhanced contrast microscopy
Cell-rolling Velocity
Cell Pore Size Determination
TEM
SEM
Cell Deformation
Micropipet Technique
Optical Trapping
Cell Shear Stress
Cone and Plate
Fluorescent Ratiometric Imaging
Cell Adhesion
Laser Trap
Interferometry
SEM
Cell Migration
4-D Image Processing System
Cell Uptake
Nanovid Microscopy
Electroporation
Cell Protein Secretion
Atomic Force Microscopy
Fluorescence Lifetime Imaging
Fluorescence Recovery after Photobleaching
Cell Proliferation
Radiation Monitoring
Fluorescence Microscopy
Cell Differentiation
Fluorescence Ratio Imaging
Cell Sorter
Cell Signaling and Regulation
Fluorescence In-Situ Hybridization (FISH)
Radioactive Labeling
Problems
References
Nervous System
Cell Potential
Resting Potential
Action Potential
Brain, EEG, and Evoked Potentials
Anatomy and Function of the Brain
Electroencephalography (EEG)
Evoked Potentials
Brain Imaging: X ray
Brain Imaging: CT
Brain Imaging: MRI
Brain Imaging: Nuclear Imaging
Brain Imaging: Single-Photon Emission Computed Tomography (SPECT)
Brain Imaging: Positron Emission Tomography (PET)
Brain Imaging: Biomagnetism
Eye, ERG, EOG, and Visual Field
Electroretinogram (ERG)
Electro-Oculogram (EOG)
Visual Field
Eye Pressure
Ophthalmoscopy
Ears and Audiometry
The Ears
Audiometry
Otoscopy
Muscles
Muscle Contraction, Length and Force
Electromyography (EMG)
Neuromuscular Performance
Problems
References
Heart and Circulation
Cardiac Anatomy and Physiology
Heart Valves
Cardiac Cycle
Cardiac Excitation and Control
Cardiac Biopotentials
Electrodes
Electrocardiogram
Electrograms
Cardiac Pressures
Strain Gage
Catheter
Cardiac Output
Fick Method
Thermodilution
Dye Dilution
Radionuclide Angiography
Echocardiography
Magnetic Resonance Imaging (MRI)
Cardiac Sounds
Stethoscopes
Microphones
Myocardial Viability
Positron Emission Tomography (PET)
Thallium-201 Imaging
Myocardial Contrast Echocardiography
Circulation
Blood Flow
Dilution
Electromagnetic Flowmeter
Ultrasonic Flowmeter
Laser-Doppler Flowmeter
Blood Pressure
Indirect Measurement
Direct Measurement
Arterial tonometry
Vessel Distension
Intravascular Ultrasound
Angiography
Vessel Volume Flow
Flow Visualization
Ultrasonic Sonography
Video Microscopy
Problems
References
Lung, Kidney, Bone, and Skin
Lung
Pulmonary Volume
Measurement of Pulmonary Volume
Pulmonary Flow
Measurement of Pulmonary Flow
Pulmonary Diffusion
Pulmonary Airway Resistance
Kidney
Kidney Clearance
Creatinine
Kidney Imaging
Pyelogram
Hemodialysis
Peritoneal Dialysis
Kidney Function
Extracellular Water by Impedance
Bones and Joints
Bone Mineral Density
Stress and Strain
Strain Gage
LVDT
Soft Tissue Strain
Joint Friction
Bone Position
Bone Strain-Related Potentials
Skin
Water Loss
Color
Problems
References
Body Temperature, Heat, Fat, and Movement
Regulation of Body Temperature
Clinical Temperature Measurement
Surface Temperature Measurement
Core Temperature Measurement
Measurement of Body Heat: Calorimetry
Direct Calorimetry
Indirect Calorimetry
Measurement of Body Fat
Direct Measurement of Body Fat
Indirect Measurement of Body Fat
Measurement of Body Movement
Goniometers and Accelerometers
Video and Optoelectronic Systems
Problems
References
Index

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