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Principles of Genetics

ISBN-10: 0470903597
ISBN-13: 9780470903599
Edition: 6th 2012
List price: $223.95 Buy it from $46.00
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Description: Snustad's 6th edition of Principles of Genetics offers many new and advanced features including boxed sections with the latest advances in Genetics, a streamlined roster of topics, a more reader-friendly layout, and new problem-solving supplements.   More...

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Book details

List price: $223.95
Edition: 6th
Copyright year: 2012
Publisher: John Wiley & Sons, Incorporated
Publication date: 8/23/2011
Binding: Hardcover
Pages: 784
Size: 9.25" wide x 10.75" long x 1.25" tall
Weight: 4.422
Language: English

Snustad's 6th edition of Principles of Genetics offers many new and advanced features including boxed sections with the latest advances in Genetics, a streamlined roster of topics, a more reader-friendly layout, and new problem-solving supplements. Furthermore, this new edition includes more problem solving within each chapter through the Test Your Problem Solving Skills feature and a Solve It icon to prompt readers to go online to WileyPlus for animated tutorials. A new one-column design better showcases important pieces of art and avoids the "overwhelmed" reaction readers have to the crowded layouts found in many other texts. Boxed sections reduce in size to help maintain the flow of the text and the Focus On boxes are revised to include the most current developments in genetics as well as most relevant topics.

The Science of Genetics
An Invitation
Three Great Milestones in Genetics
DNA as the Genetic Material
Genetics and Evolution
Levels of Genetic Analysis
Genetics in the World: Applications of Genetics to Human Endeavors
Cellular Reproduction
Cells and Chromosomes
Mitosis
Meiosis
Life Cycles of Some Model Genetic Organisms
Mendelism: The Basic Principles of Inheritance
Mendel���s Study of Heredity
Applications of Mendel���s Principles
Testing Genetic Hypotheses
Mendelian Principles in Human Genetics
Extensions of Mendelism
Allelic Variation and Gene Function
Gene Action: From Genotype to Phenotype
Inbreeding: Another Look at Pedigrees
The Chromosomal Basis of Mendelism
Chromosomes
The Chromosome Theory of Heredity
Sex-Linked Genes in Humans
Sex Chromosomes and Sex
Determination
Dosage Compensation of X-Linked Genes
Variation in Chromosome Number and Structure
Cytological Techniques
Polyploidy
Aneuploidy
Rearrangements of Chromosome Structure
Linkage, Crossing Over, and Chromosome Mapping in Eukaryotes
Linkage, Recombination, and Crossing Over
Chromosome Mapping
Cytogenetic Mapping
Linkage Analysis in Humans
Recombination and Evolution
The Genetics of Bacteria and Their Viruses
Viruses and Bacteria in Genetics
The Genetics of Viruses
The Genetics of Bacteria
Mechanisms of Genetic Exchange in Bacteria
The Evolutionary Significance of Genetic Exchange in Bacteria
DNA and the Molecular Structure of Chromosomes
Functions of the Genetic Material
Proof That Genetic Information Is Stored in DNA
The Structures of DNA and RNA
Chromosome Structure in Prokaryotes and Viruses
Chromosome Structure in Eukaryotes
Replication of DNA and Chromosomes
Basic Features of DNA Replication In Vivo
DNA Replication in Prokaryotes
Unique Aspects of Eukaryotic Chromosome Replication
Transcription and RNA Processing
Transfer of Genetic Information: The Central Dogma
The Process of Gene Expression
Transcription in Prokaryotes
Transcription and RNA Processing in Eukaryotes
Interrupted Genes in Eukaryotes: Exons and Introns
Removal of Intron Sequences by RNA Splicing
Translation and the Genetic Code
Protein Structure
One Gene—One Colinear Polypeptide
Protein Synthesis: Translation
The Genetic Code
Codon-tRNA Interactions
Mutation, DNA Repair, and Recombination
Mutation: Source of the Genetic Variability Required for Evolution
The Molecular Basis of Mutation
Mutation: Basic Features of the Process
Mutation: Phenotypic Effects
Assigning Mutations to Genes by the Complementation Test
Screening Chemicals for Mutagenicity: The Ames Test
DNA Repair Mechanisms
Inherited Human Diseases with Defects in DNA Repair
DNA Recombination Mechanisms
The Techniques of Molecular Genetics
Basic Techniques Used to Identify, Amplify, and Clone Genes
Construction and Screening of DNA Libraries
The Molecular Analysis of DNA, RNA, and Protein
The Molecular Analysis of Genes and Chromosomes
Genomics
Genomics: An Overview
Correlated Genetic, Cytological, and Physical Maps of Chromosomes
Map Position-Based Cloning of Genes
The Human Genome Project
RNA and Protein Assays of Genome Function
Comparative Genomics
Applications of Molecular Genetics
Use of Recombinant DNA Technology to Identify Human Genes and Diagnose Human Diseases
Molecular Diagnosis of Human Diseases
Human Gene Therapy
DNA Profiling
Production of Eukaryotic Proteins in Bacteria
Transgenic Plants and Animals
Reverse Genetics: Dissecting Biological Processes by Inhibiting Gene Expression
Transposable Genetic Elements
Transposable Elements: An Overview
Transposable Elements in Bacteria
Cut-and-Paste Transposons in Eukaryotes
Retroviruses and Retrotransposons
Transposable Elements in Humans
The Genetic and Evolutionary Significance of Transposable Elements
Regulation of Gene Expression in Prokaryotes
Constitutive, Inducible, and Repressible Gene Expression
Positive and Negative Control of Gene Expression
Operons: Coordinately Regulated Units of Gene Expression
The Lactose Operon in E. coli: Induction and Catabolite Repression
The Tryptophan Operon in E. coli: Repression and Attenuation
Translational Control of Gene Expression
Posttranslational Regulatory Mechanisms
Regulation of Gene Expression in Eukaryotes
Ways of Regulating Eukaryotic Gene Expression: An Overview
Induction of Transcriptional Activity by Environmental and Biological Factors
Molecular Control of Transcription in Eukaryotes
Posttranscriptional Regulation of Gene Expression by RNA Interference
Gene Expression and Chromatin Organization
Activation and Inactivation of Whole Chromosomes
The Genetic Control of Animal Development
A Genetic Perspective on Development
Maternal Gene Activity in Development
Genetic Analysis of Development in Vertebrates
The Genetic Basis of Cancer
Cancer: A Genetic Disease
Oncogenes
Tumor Suppressor Genes
Genetic Pathways to Cancer
Inheritance of Complex Traits
Complex Traits
Statistics of Quantitative Genetics
Analysis of Quantitative Traits
Correlations Between Relatives
Quantitative Genetics of Human Behavioral Traits
Population Genetics
The Theory of Allele Frequencies
Natural Selection
Random Genetic Drift
Populations in Genetic Equilibrium
Evolutionary Genetics
The Emergence of Evolutionary Theory
Genetic Variation in Natural Populations
Molecular Evolution
Speciation
Human Evolution
Appendices
The Rules of Probability
Binomial Probabilities
In Situ Hybridization
Evidence for an Unstable Messenger RNA
Evolutionary Rates
Answers to Odd-Numbered Questions and Problems
Glossary
Photo Credits
Illustration Credits
Index

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