| |
| |
| |
Inorganic Chemistry Basics | |
| |
| |
| |
Crystal field theory | |
| |
| |
| |
Molecular orbital theory | |
| |
| |
| |
Absorption spectra of metal complexes | |
| |
| |
| |
Magnetic properties of metal complexes | |
| |
| |
| |
Reactions of metal complexes | |
| |
| |
| |
Bibliography | |
| |
| |
| |
References | |
| |
| |
| |
Problems | |
| |
| |
| |
Metallo-Drugs and Their Action | |
| |
| |
| |
Introduction | |
| |
| |
| |
Proteins as Targets for Metallo-Drugs | |
| |
| |
| |
DNA as a target for Metallo-Drugs | |
| |
| |
| |
Reactions of Metal Complexes in the Biological Milieu | |
| |
| |
| |
Evaluating the Pharmacological Effects of Agents | |
| |
| |
| |
From Discovery to the Marketplace and Beyond | |
| |
| |
| |
Bibliography | |
| |
| |
| |
References | |
| |
| |
| |
Problems | |
| |
| |
| |
Cisplatin | |
| |
| |
| |
Physical and Chemical Properties of Cisplatin | |
| |
| |
| |
Formulation, Administration, and Pharmacokinetics | |
| |
| |
| |
Reaction of Cisplatin in Biological Media | |
| |
| |
| |
Uptake, Cytotoxicity, and Resistance | |
| |
| |
| |
Interaction of Cisplatin with Cellular Targets | |
| |
| |
| |
Bibliography | |
| |
| |
| |
References | |
| |
| |
| |
Problems | |
| |
| |
| |
Platinum Anticancer Drugs | |
| |
| |
| |
Carboplatin | |
| |
| |
| |
Oxaliplatin | |
| |
| |
| |
New Platinum Agents | |
| |
| |
| |
Bibliography | |
| |
| |
| |
References | |
| |
| |
| |
Problems | |
| |
| |
| |
Ruthenium, Titanium, and Gallium for Treating Cancer | |
| |
| |
| |
Ruthenium for Treating Cancer | |
| |
| |
| |
Titanium Compound for Treating Cancer | |
| |
| |
| |
Gallium for Treating Cancer | |
| |
| |
| |
Bibliography | |
| |
| |
| |
References | |
| |
| |
| |
Problems | |
| |
| |
| |
Gold Compounds for Treating Arthritis, Cancer, and Other Diseases | |
| |
| |
| |
Chemistry of Gold in Biological Media | |
| |
| |
| |
Gold Complexes for Treating Cancer | |
| |
| |
| |
Gold Complexes for Treating AIDS and Other Diseases | |
| |
| |
| |
Bibliography | |
| |
| |
| |
References | |
| |
| |
| |
Problems | |
| |
| |
| |
Vanadium, Copper, and Zinc in Medicine | |
| |
| |
| |
Vanadium for Treating Diabetes | |
| |
| |
| |
Copper and Alzheimer's Disease | |
| |
| |
| |
Copper in Wilson's and Menkes Diseases | |
| |
| |
| |
Zinc-Bicyclam. A Cytokine Receptor Antagonist | |
| |
| |
| |
Bibliography | |
| |
| |
| |
References | |
| |
| |
| |
Problems | |
| |
| |
| |
Metal Complexes for Diagnosing Disease | |
| |
| |
| |
Technetium-99m in diagnostic nuclear medicine | |
| |
| |
| |
Metal compounds as contrast agents for MRI | |
| |
| |
| |
Radionuclides for palliative care and cancer treatment | |
| |
| |
| |
Bibliography | |
| |
| |
| |
References | |
| |
| |
| |
Problems | |
| |
| |
| |
Nanomedicine | |
| |
| |
| |
Nanoscience in Treating Disease | |
| |
| |
| |
Nanoscience in Diagnosing Disease | |
| |
| |
| |
Potential Health Risks of Nanoparticles | |
| |
| |
| |
Sources | |
| |
| |
| |
Literature Cited | |
| |
| |
| |
Problems | |
| |
| |
Index | |