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Introduction to Biostatistics | |

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Introduction | |

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Some Basic Concepts | |

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Measurement and Measurement Scales | |

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Sampling and Statistical Inference | |

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The Scientific Method and the Design of Experiments | |

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Computers and Biostatistical Analysis | |

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Summary | |

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Review Questions and Exercises | |

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References | |

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Descriptive Statistics | |

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Introduction | |

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The Ordered Array | |

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Grouped Data: The Frequency Distribution | |

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Descriptive Statistics: Measures of Central Tendency | |

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Descriptive Statistics: Measures of Dispersion | |

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Summary | |

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Review Questions and Exercises | |

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References | |

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Some Basic Probability Concepts | |

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Introduction | |

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Two Views of Probability: Objective and Subjective | |

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Elementary Properties of Probability | |

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Calculating the Probability of an Event | |

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Bayes' Theorem, Screening Tests, Sensitivity, Specificity, and Predictive Value Positive and Negative | |

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Summary | |

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Review Questions and Exercises | |

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References | |

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Probability Distributions | |

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Introduction | |

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Probability Distributions of Discrete Variables | |

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The Binomial Distribution | |

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The Poisson Distribution | |

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Continuous Probability Distributions | |

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The Normal Distribution | |

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Normal Distribution Applications | |

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Summary | |

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Review Questions and Exercises | |

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References | |

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Some Important Sampling Distributions | |

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Introduction | |

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Sampling Distributions | |

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Distribution of the Sample Mean | |

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Distribution of the Difference Between Two Sample Means | |

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Distribution of the Sample Proportion | |

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Distribution of the Difference Between Two Sample Proportions | |

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Summary | |

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Review Questions and Exercises | |

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References | |

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Estimation | |

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Introduction | |

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Confidence Interval for a Population Mean | |

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The t Distribution | |

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Confidence Interval for the Difference Between Two Population Means | |

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Confidence Interval for a Population Proportion | |

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Confidence Interval for the Difference Between Two Population Proportions | |

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Determination of Sample Size for Estimating Means | |

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Determination of Sample Size for Estimating Proportions | |

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Confidence Interval for the Variance of a Normally Distributed Population | |

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Confidence Interval for the Ratio of the Variances of Two Normally Distributed Populations | |

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Summary | |

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Review Questions and Exercises | |

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References | |

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Hypothesis Testing | |

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Introduction | |

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Hypothesis Testing: A Single Population Mean | |

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Hypothesis Testing: The Difference Between Two Population Means | |

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Paired Comparisons | |

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Hypothesis Testing: A Single Population Proportion | |

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Hypothesis Testing: The Difference Between Two Population Proportions | |

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Hypothesis Testing: A Single Population Variance | |

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Hypothesis Testing: The Ratio of Two Population Variances | |

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The Type II Error and the Power of a Test | |

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Determining Sample Size to Control Type II Errors | |

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Summary | |

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Review Questions and Exercises | |

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References | |

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Analysis of Variance | |

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Introduction | |

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The Completely Randomized Design | |

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The Randomized Complete Block Design | |

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The Repeated Measures Design | |

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The Factorial Experiment | |

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Summary | |

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Review Questions and Exercises | |

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References | |

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Simple Linear Regression and Correlation | |

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Introduction | |

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The Regression Model | |

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The Sample Regression Equation | |

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Evaluating the Regression Equation | |

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Using the Regression Equation | |

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The Correlation Model | |

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The Correlation Coefficient | |

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Some Precautions | |

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Summary | |

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Review Questions and Exercises | |

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References | |

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Multiple Regression and Correlation | |

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Introduction | |

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The Multiple Linear Regression Model | |

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Obtaining the Multiple Regression Equation | |

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Evaluating the Multiple Regression Equation | |

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Using the Multiple Regression Equation | |

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The Multiple Correlation Model | |

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Summary | |

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Review Questions and Exercises | |

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References | |

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Regression Analysis: Some Additional Techniques | |

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Introduction | |

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Qualitative Independent Variables | |

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Variable Selection Procedures | |

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Logistic Regression | |

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Summary | |

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Review Questions and Exercises | |

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References | |

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The Chi-Square Distribution and the Analysis of Frequencies | |

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Introduction | |

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The Mathematical Properties of the Chi-Square Distribution | |

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Tests of Goodness-of-Fit | |

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Tests of Independence | |

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Tests of Homogeneity | |

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The Fisher Exact Test | |

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Relative Risk, Odds Ratio, and the Mantel-Haenszel Statistic | |

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Survival Analysis | |

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Summary | |

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Review Questions and Exercises | |

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References | |

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Nonparametric and Distribution-Free Statistics | |

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Introduction | |

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Measurement Scales | |

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The Sign Test | |

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The Wilcoxon Signed-Rank Test for Location | |

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The Median Test | |

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The Mann-Whitney Test | |

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The Kolmogorov-Smirnov Goodness-of-Fit Test | |

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The Kruskal-Wallis One-Way Analysis of Variance by Ranks | |

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The Friedman Two-Way Analysis of Variance by Ranks | |

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The Spearman Rank Correlation Coefficient | |

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Nonparametric Regression Analysis | |

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Summary | |

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Review Questions and Exercises | |

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References | |

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Vital Statistics | |

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Introduction | |

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Death Rates and Ratios | |

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Measures of Fertility | |

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Measures of Morbidity | |

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Summary | |

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Review Questions and Exercises | |

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References | |

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Statistical Tables | |

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Answers to Odd-Numbered Exercises | |

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Index | |