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| Preface | |
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| A GC/MS Primer | |
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| Introduction | |
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| Why Use GC/MS? | |
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| Interpretation of Fragmentation Data Versus Spectral Library Searching | |
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| The Gas Chromatograph/Mass Spectrometer | |
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| Systems and Costs | |
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| Competitive Analytical Systems | |
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| Sample Preparation and Introduction | |
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| Direct Sample Injection into the Mass Spectrometer | |
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| Sample Purification | |
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| Manual GC Injection | |
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| Automated GC/MS Injection | |
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| The Gas Chromatography | |
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| The GC Oven and Temperature Control | |
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| Selecting GC Columns | |
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| Separation Parameters and Resolution | |
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| GC Control Variables | |
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| Derivatives | |
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| The Mass Spectrometer | |
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| Vacuum Pumps | |
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| Interfaces and Sources | |
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| Quadrupole Operation | |
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| The Ion Detector | |
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| Getting Started in GC/MS | |
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| Mode Selection | |
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| Setting Up | |
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| Mass Spectrometer Tuning and Calibration | |
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| Sample Injection and Chromatographic Separation | |
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| Data Collection Processing | |
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| A GC/MS Optimization | |
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| Chromatographic Methods Development | |
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| Isothermal Operation | |
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| Linear Temperature Gradients | |
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| Assisted Re-Equilibration | |
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| Hinge Point Gradient Modification | |
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| Pressure Gradient Development | |
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| Column Replacement | |
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| Mass Spectrometer Setup and Operation | |
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| Mass Spectrometer Calibration with Calibration Gases | |
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| Mass Axis Tuning | |
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| System Tuning for Environmental Analysis | |
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| Acquiring Information | |
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| Data Displays and Library Searches | |
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| Data Processing and Network Interfacing | |
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| Peak Identification and Integration | |
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| Multi-Instrument Control | |
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| Networking Connection | |
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| Replacement Control and Processing Systems | |
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| File Conversion and Data File Exchange | |
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| Data Re-Entry and Transcription Errors | |
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| System Maintenance and Troubleshooting | |
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| Gas Chromatograph Maintenance | |
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| Mass Spectrometer Maintenance | |
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| System Electrical Grounding | |
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| Specific Applications of GC/MS | |
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| GC/MS in The Environmental Laboratory | |
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| Volatile Organic Analysis: EPA Method 624 | |
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| SemiVolatile Organic Analysis: EPA Method 625 | |
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| EPA and State Reporting Requirements | |
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| GC/MS in Forensics, Toxicology, and Space Science | |
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| Forensic Analysis | |
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| Clinical Drug Analysis | |
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| Arson and Security Analysis | |
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| Astrochemistry | |
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| An Introduction to Structural Interpretation | |
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| History of the Sample | |
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| Elemental Composition | |
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| Search for Logical Fragmentation Intervals | |
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| Ion Trap GC/MS Systems | |
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| Ion Trap Components | |
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| Ion Trap Operation | |
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| The Linear Ion Trap Analyzer | |
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| Ion Traps in the Environmental Laboratory | |
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| Chemical Ionization in the Ion Trap | |
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| Ion Trap GC/MS/MS | |
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| Other GC/MS Systems | |
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| Sequential Mass Spectrometry (Triple-Quadrupole or Tandem GC/MS) | |
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| Magnetic Sector Systems | |
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| Laser Time-of-Flight (GC/TOF-MS) GC/MS Systems | |
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| Fourier Transform (GC/FT-MS) GC/MS Systems | |
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| An Introduction to LC/MS | |
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| Liquid Interfacing into the Mass Spectrometer | |
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| Electrospray and Nano-Spray LC/MS | |
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| Ion Spray LC/MS | |
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| LC/MS/MS | |
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| LC/MS Versus GC/MS | |
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| Innovation in GC/MS | |
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| Microfludics in GC/MS | |
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| Resistance Column Heating | |
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| Portable Gas Supply | |
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| Portable GC/MS Systems | |
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| New Column Technology | |
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| GC/MS Frequently Asked Questions | |
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| GC FAQs | |
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| Column FAQs | |
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| MS FAQs | |
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| GC/MS FAQs | |
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| GC/MS Troubleshooting Quick Reference | |
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| GC Injector Problems | |
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| GC Column Problems | |
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| MS Vacuum and Power Problems | |
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| MS Source and Calibration Problems | |
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| MS Sensitivity and Detector Problems | |
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| Sources of GC/MS Background Contamination | |
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| A Glossary of GC/MS Terms | |
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| GC/MS Selected Reading List | |
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| Journals | |
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| Books | |
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| Index | |