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Bios Instant Notes in Molecular Biology

ISBN-10: 0415684161
ISBN-13: 9780415684163
Edition: 4th 2012 (Revised)
List price: $21.00 Buy it from $20.46
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Description: BIOS Instant Notes Molecular Biology, Fourth Edition, is the perfect text for undergraduates looking for a concise introduction to the subject, or a study guide to use before examinations. Each topic begins with a summary of essential facts-an ideal  More...

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Book details

List price: $21.00
Edition: 4th
Copyright year: 2012
Publisher: Taylor & Francis Group
Publication date: 5/3/2012
Binding: Paperback
Pages: 392
Size: 6.75" wide x 9.50" long x 0.75" tall
Weight: 0.638
Language: English

BIOS Instant Notes Molecular Biology, Fourth Edition, is the perfect text for undergraduates looking for a concise introduction to the subject, or a study guide to use before examinations. Each topic begins with a summary of essential facts-an ideal revision checklist-followed by a description of the subject that focuses on core information, with clear, simple diagrams that are easy for students to understand and recall in essays and exams.  BIOS Instant Notes Molecular Biology, Fourth Edition, is fully up-to-date and covers:Information processing and macromoleculesProperties of nucleic acidsProkaryotic and eukaryotic chromosome structureDNA replicationDNA damage, repair and recombinationTranscription in prokaryotesRegulation of transcription in prokaryotesTranscription in eukaryotesRegulation of transcription in eukaryotesRNA processing and RNPsThe genetic code and tRNAProtein synthesisBacteriophages and eukaryotic virusesCell cycle and cancerGene manipulationCloning VectorsGene libraries and screeningAnalysis and uses of cloned DNAFunctional genomics and the new technologies

Preface to the fourth edition
Informational macromolecules
Information processing and molecular biology
Nucleic acid structure and function
Protein structure and function
Macromolecular assemblies
Analysis of proteins
Properties of nucleic acids
Chemical and physical properties of nucleic acids
Spectroscopic and thermal properties of nucleic acids
DNA supercoiling
Prokaryotic and eukaryotic chromosome structure
Prokaryotic chromosome structure
Chromatin structure
Eukaryotic chromosome structure
Genome complexity
DNA replication
DNA replication: an overview
Bacterial DNA replication
Eukaryotic DNA replication
DNA damage, repair, and recombination
DNA damage
Mutagenesis
DNA repair
Recombination and transposition
Transcription in bacteria
Basic principles of transcription
Escherichia coli RNA polymerase
The E. coli �<sup>70</sup> promoter
Transcription initiation, elongation, and termination
Regulation of transcription in bacteria
The lac operon
The trp operon
Transcriptional regulation by alternative a factors and RNA
Transcription in eukaryotes
The three RNA polymerases: characterization and function
RNA Pol I genes: the ribosomal repeat
RNA Pol III genes: 5S and tRNA transcription
RNA Pol II genes: promoters and enhancers
General transcription factors and RNA Pol II initiation
Regulation of transcription in eukaryotes
Eukaryotic transcription factors
Examples of transcriptional regulation
RNA processing and RNPs
rRNA processing and ribosomes
tRNA and other small RNA processing
mRNA processing, hnRNPs, and snRNPs
Alternative mRNA processing
The genetic code and tRNA
The genetic code
tRNA structure and function
Protein synthesis
Aspects of protein synthesis
Mechanism of protein synthesis
Initiation in eukaryotes
Translational control and post-translational events
Bacteriophages and eukaryotic viruses
Introduction to viruses
Bacteriophages
DNA viruses
RNA viruses
Cell cycle and cancer
The cell cycle
Oncogenes
Tumor suppressor genes
Apoptosis
Gene manipulation
DNA cloning: an overview
Preparation of plasmid DNA
Restriction enzymes and electrophoresis
Ligation, transformation, and analysis of recombinants
Cloning vectors
Design of plasmid vectors
Bacteriophages, cosmids, YACs, and BACs
Eukaryotic vectors
Gene libraries and screening
Genomic libraries
cDNA libraries
Screening procedures
Analysis and uses of cloned DNA
Characterization of clones
Nucleic acid sequencing
Polymerase chain reaction
Analysis of cloned genes
Mutagenesis of cloned genes
Functional genomics and the new technologies
Introduction to the 'omics
Global gene expression analysis
Proteomics
Cell and molecular imaging
Transgenics and stem cell technology
Bioinformatics
Systems and synthetic biology
Further reading
Abbreviations
Index

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