Textbook of Drug Design and Discovery

ISBN-10: 0415282888
ISBN-13: 9780415282888
Edition: 3rd 2002 (Revised)
List price: $89.95
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Description: This volume provides a complete source of information on all facets of drug design. It follows drug design from the initial structure-activity relationship to the final processes of clinical evaluation and registration.

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Book details

List price: $89.95
Edition: 3rd
Copyright year: 2002
Publisher: CRC Press LLC
Publication date: 7/25/2002
Binding: Paperback
Pages: 592
Size: 6.75" wide x 9.50" long x 1.75" tall
Weight: 3.696
Language: English

This volume provides a complete source of information on all facets of drug design. It follows drug design from the initial structure-activity relationship to the final processes of clinical evaluation and registration.

List of contributors
Preface
Drug design and discovery: an overview
Roke of noodecular recognition in drug design
Stereochemistry in drug design
Computer-aided development and use of three-dimensional pharmacophore models
Quantitative structure-activity relationships and experimental design
Receptors: structure, function and pharmacology
Ion channels: structure, function and pharmacology
Radiotracers: synthesis and use in imaging
Excitatory and inhibitory amino acid receptor ligands
Acetylcholine and histamine receptors and receptor ligands: medicinal chemistry and therapeutic aspects
Dopamine and serotonin receptor and transporter ligands
Enzymes and enzyme inhibitors
Metals in medicine: inorganic medicinal chemistry
Design and application of prodrugs
Peptides and peptidomimetics
Classical antiviral agents and design of new antiviral agents
Anticancer agents
Index

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