Renal Physiology Mosby Physiology Monograph Series (with Student Consult Online Access)

ISBN-10: 0323086918

ISBN-13: 9780323086912

Edition: 5th 2012

List price: $46.95
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Description: This volume in the Mosby Physiology Monograph Series explains the fundamentals of renal physiology in a clear and concise manner. It provides you with a basic understanding of normal kidney function at the cellular and molecular level. Attractively illustrated with clear 2-color diagrams, this volume also facilitates study with learning objectives, overview boxes, chapter summaries, and clinical cases with questions and explained answers. Plus, online access via STUDENT CONSULT makes this an even more powerful learning resource.Stay current with clear, accurate, and up-to-the-minute coverage of the physiology of normal renal function focusing on the needs of the student.Bridge the gap between normal function and disease with pathophysiology content throughout the book.Master the material more easily with learning objectives, overview boxes, key words and concepts, chapter summaries, and clinical cases with questions and explained answers.Understand complex concepts by examining more than 250 clear, 2-color diagrams.Apply what you've learned to real-life clinical situations using featured clinical commentaries.Includes STUDENT CONSULT access at no additional charge, enabling you to consult the book online, anywhere you go · perform quick searches · add your own notes and bookmarks · follow Integration Links to related bonus content from other STUDENT CONSULT titles-to help you see the connections between diverse disciplines · and more!(1) Revise and update the content of all chapters(2) Revise and update the figures (perhaps 10% new figures, replacing old figures)(3) Revise and update the Appendices (notably the test questions, which we think should bereorganized by chapter-students always ask us for more questions-so we willincrease by 50 questions).(4) Eliminate key words at the end of chapters and -replace them with "clinical pearls", i.e., esstential points that have aclinical relevance(5) Review and revise the clinical cases (we will run themby our clinical colleagues)(6) Label the inserts clinical and basicscience like we do in B&L.

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Book details

List price: $46.95
Edition: 5th
Copyright year: 2012
Publisher: Elsevier - Health Sciences Division
Publication date: 10/31/2012
Binding: Paperback
Pages: 256
Size: 7.50" wide x 9.25" long x 0.25" tall
Weight: 1.100
Language: English

Introduction to the Kidney
Physiology of Body Fluids
Objectives
Physicochemical Properties�of Electrolyte Solutions
Molarity and Equivalence
Osmosis and Osmotic Pressure
Osmolarity and Osmolality
Tonicity
Oncotic Pressure
Specific Gravity
Volumes of Body Fluid Compartments
Composition of Body Fluid Compartments
Fluid Exchange Between Body Fluid Compartments
Capillary Fluid Exchange
Cellular Fluid Exchange
Summary
Key Words and Concepts
Self-Study Problems
Structure and Function of the Kidneys
Objectives
Structure of the Kidneys
Gross Anatomy
Ultrastructure of the Nephron
Ultrastructure of the Glomerulus
Ultrastructure of the Juxtaglomerular Apparatus
Innervation of the Kidneys
Summary
Key Words and Concepts
Self-Study Problems
Glomerular Filtration and Renal Blood Flow
Objectives
Renal Clearance
Glomerular Filtration Rate
Glomerular Filtration
Determinants of Ultrafiltrate Composition
Dynamics of Ultrafiltration
Renal Blood Flow
Regulation of Renal Blood Flow and Glomerular Filtration Rate
Sympathetic Nerves
Angiotensin II
Prostaglandins
Nitric Oxide
Endothelin
Bradykinin
Adenosine
Natriuretic Peptides
ATP
Glucocorticoids
Histamine
Dopamine
Summary
Key Words and Concepts
Self-Study Problems
Renal Transport Mechanisms: NaCl and Water�Reabsorption Along the Nephron
Objectives
General Principles of Membrane Transport
General Principles of Transepithelial Solute and Water Transport
NaCl, Solute, and Water Reabsorption Along the Nephron
Proximal Tubule
Henle's Loop
Distal Tubule and Collecting Duct
Regulation of NaCl and Water Reabsorption
Summary
Key Words and Concepts
Self-Study Problems
Regulation of Body Fluid Osmolality: Regulation of Water Balance
Objectives
Antidiuretic Hormone
Osmotic Control of�AVP Secretion
Hemodynamic Control of�AVP Secretion
AVP�Actions on the Kidneys
Thirst
Renal Mechanisms for Dilution and Concentration of the Urine
The Role of Urea
Vasa Recta Function
Assessment of Renal Diluting and Concentrating Ability
Summary
Key Words and Concepts
Self-Study Problems
Regulation of Extracellular Fluid Volume and NaCl Balance
Objectives
Concept of Effective Circulating Volume
Volume-Sensing Systems
Volume Sensors in the Low-Pressure Cardiopulmonary Circuit
Volume Sensors in the High-Pressure Arterial Circuit
Hepatic Sensors
Central Nervous System Na+ Sensors
Volume Sensor Signals
Renal Sympathetic Nerves
Renin-Angiotensin-Aldosterone System
Natriuretic Peptides
AVP
Control of Renal NaCl Excretion During Euvolemia
Mechanisms for Maintaining�Constant Na+ Delivery to the Distal Tubule
Regulation of Distal Tubule and Collecting Duct Na+ Reabsorption
Control of Na+ Excretion with Volume Expansion
Control of Na+ Excretion with Volume Contraction
Edema
Alterations in Starling Forces
The Role of the Kidneys
Summary
Key Words and Concepts
Self-Study Problems
Regulation of Potassium Balance
Objectives
Overview of K+ Homeostasis
Regulation of Plasma�[K+]
Epinephrine
Insulin
Aldosterone
Alterations of Plasma�[K+]
Acid-Base Balance
Plasma Osmolality
Cell Lysis
Exercise
K+ Excretion by the Kidneys
Cellular Mechanisms of K+ Transport by Principal Cells and Intercalated Cells in the Distal Tubule and Collecting Duct
Regulation of K+ Secretion by the Distal Tubule and Collecting Duct
Plasma [K+]
Aldosterone
Arginine vasopressin (AVP)
Factors that Perturb K+ Excretion
Flow of Tubular Fluid
Acid-Base Balance
Glucocorticoids
Summary
Key Words and Concepts
Self-Study Problems
Regulation of Acid-Base Balance
Objectives
The HCO3- Buffer System
Overview of Acid-Base Balance
Renal Net Acid Excretion
HCO3- Reabsorption Along the Nephron
Regulation of�H+ Secretion
Formation of New HCO3-
Response to Acid-Base Disorders
Extracellular and Intracellular Buffers
Respiratory Compensation
Renal Compensation
Simple Acid-Base Disorders
Metabolic Acidosis
Metabolic Alkalosis
Respiratory Acidosis
Respiratory Alkalosis
Analysis of Acid-Base Disorders
Summary
Key Words and Concepts
Self-Study Problems
Regulation of Calcium and Phosphate Homeostasis
Objectives
Calcium
Overview of Ca++ Homeostasis
Ca++ Transport along the Nephron
Regulation of Urinary Ca++ Excretion
Calcium-Sensing Receptor
Phosphate
Overview of Pi Homeostasis
Pi Transport along the Nephron
Regulation of Urinary Pi Excretion
Integrative Review of Parathyroid Hormone, Calcitriol, and Calcitonin on Ca++ and Pi Homeostasis
Summary
Key Words and Concepts
Self-Study Problems
Physiology of Diuretic Action
Objectives
General Principles of Diuretic Action
Sites of Action of Diuretics
Response of Other Nephron Segments
Adequate Delivery of Diuretics to Their Site of Action
Volume of the Extracellular Fluid
Diuretic Braking Phenomenon
Mechanisms of Action of Diuretics
Osmotic Diuretics
Carbonic Anhydrase Inhibitors
Loop Diuretics
Thiazide Diuretics
K+-Sparing Diuretics
Aquaretics
Effect of Diuretics on the Excretion of Water and Other Solutes
Solute-Free Water
K+ Excretion
HCO3- Excretion
Ca++ and Pi Excretion
Summary
Key Words and Concepts
Self-Study Problems
Additional Reading
Integrative Case Studies
Normal Laboratory Values
Nephron Function
Answers to Self-Study Problems
Answers to Integrative Case Studies
Review Examination
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