Endocrine Physiology

ISBN-10: 032303666X

ISBN-13: 9780323036665

Edition: 3rd 2007 (Revised)

List price: $45.95
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Description: This volume in the Mosby Physiology Monograph Series explains the fundamentals of endocrine physiology in a clear and concise manner. It provides you with a basic understanding of how the endocrine system functions in health and disease. Attractively illustrated with clear 2-color diagrams, this volume also facilitates study with learning objectives, overview boxes, chapter summaries, and clinical cases with questions and explained answers. Plus, online access via STUDENT CONSULT makes this an even more powerful learning resource. Stay current with clear, accurate, and up-to-the-minute coverage of the physiology of the endocrine system focusing on the needs of the student. Bridge the gap between normal function and disease with pathophysiology content throughout the book. Master the material more easily with learning objectives, overview boxes, key words and concepts, chapter summaries, and clinical cases with questions and explained answers. Understand complex concepts by examining more than 200 clear, 2-color diagrams. Apply what youve learned to real-life clinical situations using featured clinical commentaries. Includes STUDENT CONSULT access at no additional charge, enabling you to consult the book online, anywhere you go perform quick searches add your own notes and bookmarks follow Integration Links to related bonus content from other STUDENT CONSULT titlesto help you see the connections between diverse disciplines and more!

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Book details

List price: $45.95
Edition: 3rd
Copyright year: 2007
Publisher: Elsevier - Health Sciences Division
Publication date: 5/25/2007
Binding: Paperback
Pages: 344
Size: 7.25" wide x 9.25" long x 0.50" tall
Weight: 1.430
Language: English

Bruce White, P h D, is the chair of the Information Systems Management Department in the School of Business, Quinnipiac University. He is very active in Information Systems Education, having served as conference chair for ISECON (Information Systems Education Conference) four times, an ABET IS accreditation visitor, on the board of directors of the Center for Computing Education Research (CCER), a lead developer for the IS Assessment Test from CCER, on the editorial review board for the Journal of Information Systems Education, and regularly reviews papers for conferences, textbook publishers and submits papers to several academic conferences. He also received the AITP-EDSIG Educator of the Year award for 2008.Andrew Pauxtis graduated from Quinnipiac University in 2007 with an undergraduate degree in Communications, and again in 2008 with a Masterrsquo;s degree in Information Systems Management. nbsp; He is the founder of Apaxmedia, Inc., an internet new media marketing company.

Introduction to the Endocrine System
Objectives
Chemical Nature of Hormones
Proteins/Peptides
Catecholamines
Steroid Hormones
Thyroid Hormones
Eicosanoids
Transport of Hormones in the Circulation
Cellular Responses to Hormones
Signalling from Membrane Receptors
Signalling from Intracellular Receptors
Hormonal Rhythms
Summary
Key Words and Concepts
Self-Study Problems
Different Modes of Chemical Signaling
The Endocrine Function of the Gastrointestinal Tract
Objectives
Enteroendocrine Hormone Families and Their Receptors
The Regulation of Gastric Function
Overview of Regulation of Gastric Secretion and Motility
Gastrin and the Stimulation of Gastric Function
Inhibition of Gastric Function
Enteroendocrine Regulation of the Exocrine Pancreas and Gall Bladder
Secretin
Cholecystokinin
Motilin and Stimulation of Gastric and Small Intestinal Contractions During the Interdigestive Period
The Insulinotropic Actions of GI Peptides (Incretin Action)
Gastric Inhibitory Peptide/ Glucose-dependent Insulinotropic Peptide
Glucagon-like Peptide-1
The Enterotropic Actions of GI Hormones
Gastrin
Secretin and CCK
GLP-1
GLP-2
Summary
Key Words and Concepts
Self-Study Problems
Energy Metabolism
Objectives
Overview of Energy Metabolism
Cells Must Make ATP to Function and Stay Viable
Making ATP
Storage Forms of Energy
Partial Digestion of VLDL Generates Cholesterol-Rich Low-Density Lipoprotein
Release of TGs in Adipose Cells
Protein
Gluconeogenesis - Making Glucose from Glycerol, Lactate and Amino Acids
Summary of Key Metabolic Pathways
Key Hormones Involved in Metabolic Homeostasis
The Endocrine Pancreas
Insulin
Glucagon
Epinephrine and Norepinephrine
Metabolic Homeostasis - The Integrated Outcome of Hormonal and Substrate/Product Regulation of Metabolic Pathways
The Fasting-to-Fed State Transition Involves Anabolic Pathways that Store Energy
Release of Energy During the Interdigestive Period or an Extended Fast
Diabetes Mellitus
Symptoms of Diabetes Mellitus
Acute Complications of Diabetes Mellitus
Long-Term Sequelae of Diabetes Mellitus
Problems Associated with Diabetes Management
Emerging Concepts in Energy Homeostasis: Adipose Tissue as an Endocrine Organ
Leptin
Adiponectin
Tumor Necrosis Factor-[alpha] (TNF-[alpha])
Summary
Key Words and Concepts
Self-Study Problems
Calcium and Phosphate Homeostasis
Objectives
Calcium and Phosphorus are Important Dietary Elements that Play Many Crucial Roles in Cellular Physiology
Physiological Regulation of Calcium and Phosphate: Parathyroid Hormone (PTH) and 1,25-dihydroxyvitamin D
Parathyroid Hormone
The Parathyroid Glands
Vitamin D
The Small Intestine, Bone, and Kidney Determine Ca[superscript 2+] and Pi Levels
Handling of Ca[superscript 2+] and Pi by the Small Intestine
Handling of Ca[superscript 2+] and Pi by Bone
The Histophysiology of Adult Bone
Handling of Ca[superscript 2+] and Pi by the Kidneys
Integrated Physiologic Regulation of Ca[superscript 2+]/Pi Metabolism: Response of PTH and 1,25-dihydroxyvitamin D to a Hypocalcemia Challenge
Pharmacologic Hormonal Regulation of Calcium and Phosphate: Calcitonin
Hormonal Regulation of Calcium and Phosphate: Regulators Overexpressed by Cancers
Regulation of Ca[superscript 2+]/Pi Metabolism by Immune/Inflammatory Cells
Regulation of Ca[superscript 2+]/Pi Metabolism by Gonadal and Adrenal Steroid Hormones
Pathologic Disorders of Calcium and Phosphate Balance
Hyperparathyroidism (Primary)
Pseudohypoparathyroidism
Hypoparathyroidism
Vitamin D Deficiency
Paget's Disease
Bone Problems of Renal Failure (Renal Osteodystrophy)
Summary
Key Words and Concepts
Self-Study Problems
The Hypothalamus-Pituitary Complex
Objectives
Embryology and Anatomy
The Neurohypophysis
Synthesis of ADH (Vasopressin) and Oxytocin
Antidiuretic Hormone
Oxytocin
The Adenohypophysis
The Endocrine Axes
The Endocrine Function of the Adenohypophysis
The Corticotrope
The Thyrotrope
The Gonadotrope
The Somatotrope
Direct Versus Indirect Actions of GH
Role of Growth Hormone, Insulin-like Growth Factor, and Insulin in Starvation
Pathologic Conditions Involving Growth Hormone
The Lactotrope
Pathologic Conditions Involving Prolactin
Hypopituitarism
Growth
Summary
Key Words and Concepts
Self-Study Problems
The Thyroid Gland
Objectives
Anatomy and Histology of the Thyroid
Thyroid Hormones
Synthesis of Thyroid Hormones
Thyroid Hormone Secretion
Compounds Altering Thyroid Hormone Synthesis
Thyroid Hormone Transport
Metabolism of Thyroid Hormones
Control of Thyroid Function
Control Mechanisms
Perturbations of Control System
Mechanisms of Hormone Action
Thyroid Hormone Receptors
Thyroid-Stimulating Hormone Receptor
Actions of Thyroid Hormones
Maturational and Differentational Effects
Neurologic Effects
Effects on Growth
Metabolic Actions
Actions Mimicking Sympathetic Nervous System Activity
Actions on Skeletal Muscle
Actions on Cardiovascular System
Pathologic Conditions Involving the Thyroid
Hypothyroidism
Hyperthyroidism
Thyroiditis
Summary
Key Words and Concepts
Self-Study Problems
Laboratory Data on Thyroid Function
The Adrenal Gland
Objectives
Anatomy
Adrenal Medulla
Synthesis of Epinephrine
Mechanism of Action of Catecholamines
Physiological Actions of Adrenomedullary Catecholamines
Metabolism of Catecholamines
Pathologic Conditions Involving the Adrenal Medulla
Adrenal Cortex
Zona Fasciculata
The Zona Fasciculata Makes Cortisol
Transport and Metabolism of Cortisol
Mechanism of Action of Cortisol
Physiologic Actions of Cortisol
Regulation of Cortisol Production
Zona Reticularis
The Zona Reticularis Makes Adrenal Androgens
Metabolism and Fate DHEAS and DHEA
Physiologic Actions of Adrenal Androgens
Regulation of Zona Reticularis Function
Zona Glomerulosa
The Zona Glomerulosa Makes Aldosterone
Transport and Metabolism of Aldosterone
Mechanism of Aldosterone Action
Physiologic Actions of Aldosterone
Regulation of Aldosterone Secretion
Pathologic Conditions Involving the Adrenal Cortex
Adrenocortical Insufficiency
Adrenocortical Excess
Summary
Key Words and Concepts
Self-Study Problems
The Male Reproductive System
Objectives
Histophysiology of the Testis
The Intratubular Compartment
The Peritubular Compartment
Fates and Actions of Androgens
Intratesticular Androgen
Peripheral Conversion to Estrogen
Peripheral Conversion to DHT
Peripheral Testosterone Actions
Mechanism of Androgen Action
Transport and Metabolism of Androgens
Hypothalamus-Pituitary-Testis Axis
Regulation of Leydig Cell Function
Regulation of Sertoli Cell Function
The Male Reproductive Tract
Development of the Male Reproductive System
Puberty and Senescence
Disorders Involving the Male Reproductive System
Summary
Key Words and Concepts
Self-Study Problems
The Female Reproductive System
Objectives
Anatomy and Histology of the Ovary
Growth, Development, and Function of the Ovarian Follicle
Resting Primordial Follicle
Growing Preantral Follicles
Growing Antral Follicles
Dominant Follicle
The Dominant Follicle During the Periovulatory Period
The Corpus Luteum
Follicular Atresia
Follicular Development and the Monthly Menstrual Cycle
Regulation of Late Follicular Development, Ovulation, and Luteinization: The Human Menstrual Cycle
The Female Reproductive Tract
The Oviduct
The Uterus
The Cervix
The Vagina
The External Genitalia
Biology of Estradiol-17[Beta] and Progesterone
Mechanisms of Estrogen and Progesterone Hormone Action
Biological Effects of Estrogen and Progesterone
Transport and Metabolism of Ovarian Steroids
The Ontogeny of the Female Reproductive System
Development of the Female Reproductive Tract
Puberty
Menopause
Ovarian Pathophysiology
Turner Syndrome
Polycystic Ovarian Syndrome
Summary
Key Words and Concepts
Self-Study Problems
Fertilization and Pregnancy
Objectives
Fertilization, Early Embryogenesis, Implantation & Placentation
Synchronization with Maternal Ovarian and Reproductive Tract Function
Fertilization
Early Embryogenesis and Implantation
Structure of Mature Placenta
The Endocrine Function of the Placenta
Human Chorionic Gonadotropin
Progesterone
Estrogen
Human Placental Lactogen
Other Placental Hormones
Placental Transport
The Fetal Endocrine System
Pancreas
Parathyroid Gland
Pituitary Gland
Thyroid Gland
Adrenal Gland
Testes and Ovaries
Maternal Endocrine Changes During Pregnancy
Pituitary Gland
Thyroid Gland
Adrenal Gland
Maternal Physiologic Changes During Pregnancy
Cardiovascular Changes
Respiratory Changes
Renal Changes
Gastrointestinal Changes
Diabetogenicity of Pregnancy
Parturition
Placental Corticotropin-Releasing Hormone and the Fetal Adrenal Axis
Estrogen and Progesterone Secretion
Oxytocin
Prostaglandins
Uterine Size
Mammogenesis and Lactation
Structure of the Mammary Gland
Hormonal Regulation of Mammary Gland Development
Contraception
Behavioral and Mechanical Approaches
Oral Contraceptives
Hormonal Treatment for Emergency Contraception and Abortion
In Vitro Fertilization
Summary
Key Words and Concepts
Self-Study Problems
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