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Preface | |
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Mouse Natural Resistance Associated Macrophage Protein 1 (Nramp1): A Key Player in Host Innate Immunity Against Infections | |
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Why Mouse Models? Nramp1: A Mouse Host Resistance Locus | |
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Pathogens Under Nramp1 Control | |
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Nramp1 Gene and Protein Expression in Macrophages | |
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The Nramp Gene Family | |
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Divalent Cation Transport by Nramp Proteins | |
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Nramp1 Dependent Divalent Cations Transport at the Phagosomal Membrane | |
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Structure/Function Studies by Site Directed Mutagenesis | |
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Divalent Cation Transport and Resistance to Infections | |
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Nramp1 and Phagosomal Maturation | |
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Genetic Susceptibility to Infectious Diseases Linked to NRAMP1 Gene in Farm Animals | |
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Comparative Genomics | |
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Nramp1 | |
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Chicken Genomics, Salmonella Infection and NRAMP1 | |
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Bovine Genomics, Brucella abortus Infection and NRAMP1 | |
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The NRAMP Genes and Human Susceptibility to Common Diseases | |
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NRAMP1 Gene Location and Structure | |
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NRAMP1 Polymorphisms | |
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NRAMP1 Function | |
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NRAMP1 and Infectious Diseases Susceptibility | |
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NRAMP1 and Autoimmune Diseases Susceptibility | |
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NRAMP2 Location and Genomic Structure | |
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NRAMP2 Functions | |
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NRAMP2 Polymorphisms | |
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NRAMP2 Polymorphisms and Human Diseases Susceptibility | |
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Pleiotropic Effects of Nramp (Bcg/Lsh/Ity) Gene Expression on Macrophage Functions | |
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Resistance to Three Pathogens Controlled by One Gene | |
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Bcg/Lsh/Ity Gene Expression in Macrophage | |
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Bcg/Lsh/Ity Gene Pleiotropic Effects on Macrophage Functions | |
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Nramp, a Candidate Gene for Bcg/Lsh/Ity Gene | |
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Impact of Nramp Gene Expression on Macrophage | |
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Signaling Activity and Functions Regulation | |
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Role of Nramp Family in Pro-Inflammatory Diseases | |
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Genetic Associations with Pro-Inflammatory Autoimmune Disease in Man | |
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Evidence for Gene x Environment Interactions? | |
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Searching for the Functional Polymorphisms in SLC11A1 | |
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Relating Disease Phenotypes to Pleiotropic Effects of SLC11A1 | |
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A Direct Role for Iron in SLC11A1 Regulated Autoimmune | |
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Disease Phenotypes? | |
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Mouse Models to Study Slc11a1 Regulation of Pro-Inflammatory Diseases | |
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Role of Nramp2 (DMT1) in Iron Homeostasis | |
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Mammalian Iron Metabolism | |
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Roles of Nramp2 (DMT1) in Iron Homeostasis | |
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Nramp2 (DMT1) in Iron Disorders | |
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Molecular Physiology of the H+-coupled Iron Transporter DMT1 | |
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Molecular Mechanisms of DMT1 | |
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Substrate Profile | |
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Structure-Function Analysis of DMT1 | |
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The Role of DMT1 in the Biology of Iron Transport | |
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Multiple Splice Forms Reveal Discrete Expression | |
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Control Mechanisms | |
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DMT1 and its Association with Human Disease | |
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Cellular and Tissue Expression of Rat DMT1 Nramp | |
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Gastrointestinal Tract | |
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Liver | |
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Erythroid Tissue | |
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Brain | |
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Kidney | |
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Placenta | |
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Tissue Distribution and Subcellular Localization of Nramp Proteins | |
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NRAMP1: Discovery of the Nramp1 Gene | |
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Tissue and Cellular Expression of Mouse and Human Nramp1 mRNA | |
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Cellular and Subcellular Expression of the Nramp1 Protein in Macrophages and in Neutrophils | |
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NRAMP2: Nramp2/DMT1 gene, RNA and Protein Isoforms | |
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Topology Model of Nramp2/DMT1 Protein | |
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Nramp2/DMT1: Ubiquitous and Cell Specific Expression | |
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Nramp2/DMT1 in Epithelial Cells | |
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Nramp2/DMT1 in Peripheral Tissues | |
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Nramp2/DMT1 Studies: Rich but Controversial Literature | |
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Plant Metal Transporters with Homology to Proteins of the NRAMP Family | |
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Genomic Analysis of the NRAMP Family in Plant Species | |
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Functional Characterization of NRAMP Metal Transport | |
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Properties in Heterologous Expression Systems | |
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NRAMP Gene Expression Pattern and Regulation in Plants | |
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Analysis of NRAMP Fun | |