Century of DNA A History of the Discovery of the Structure and Function of the Genetic Substance

ISBN-10: 0262660466
ISBN-13: 9780262660464
Edition: N/A
List price: $44.00
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Description: Why did it take more than a century of research before scientists properly understood what DNA was and what it did within the cell? A Century of DNAaims to answer this question, tracing the history of DNA research across interrelated subjects,  More...

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Book details

List price: $44.00
Publisher: MIT Press
Publication date: 6/12/1980
Binding: Paperback
Pages: 398
Size: 6.26" wide x 9.02" long x 0.91" tall
Weight: 1.408
Language: English

Why did it take more than a century of research before scientists properly understood what DNA was and what it did within the cell? A Century of DNAaims to answer this question, tracing the history of DNA research across interrelated subjects, including embryology, biophysics, organic chemistry, histology, physiological chemistry, and genetics. The chapters follow a chronological sequence in the development of ideas on DNA, and incorporate biographical material on researchers involved in these discoveries. Comprehensible to the general scientific reader and to the specialist, this book is a unique look at the foundations of molecular biology.

Franklin H. Portugal served on the scientific staff of the National Institutes of Health and was a professor at the University of Maryland University College. He is currently Clinical Associate Professor of Biology and Director of the M.S. in Biotechnology Program at The Catholic University of America in Washington, D.C. His 1979 book, A Century of DNA (MIT Press), coauthored with Jack S. Cohen, remains in print today. He worked in Nirenberg's lab from 1967 to 1970.

Foreword
Preface
Acknowledgments
The Discovery of DNA
The Role of the Nucleus
The Discovery of Nucleic Acid Components
The Tetranucleotide Hypothesis
Early Theories of Heredity
The Evolution of Modern Genetics
Genetic Transformation by DNA
The Mechanism of Gene Expression
The Search for the Chemical Structure of DNA
The Development of Structural Molecular Biology
The Three-Dimensional Structure of DNA
The Genetic Code
Conclusion and Prologue to the Second Century
Notes and References
Index

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