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Status Epilepticus Mechanisms and Management

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ISBN-10: 0262232456

ISBN-13: 9780262232456

Edition: 2006

Authors: Claude G. Wasterlain, David M. Treiman

List price: $135.00
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Description:

Interest in status epilepticus--the most extreme form of epilepsy, involving continuous seizures--has surged in the last 20 years. Since 1979 there have been over 4,000 publications on the subject, including more than 1,700 in the last five years. No other text provides such a comprehensive review of the recent advances in the field of status epilepticus. The book focuses on the two areas in which progress has been most rapid: basic mechanisms and treatment. There is now a greater understanding of the mechanisms and complications of status epilepticus at the molecular level, which should eventually lead to improved therapy, and treatment strategies today have a greater sense of urgency…    
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Book details

List price: $135.00
Copyright year: 2006
Publisher: MIT Press
Publication date: 4/7/2006
Binding: Hardcover
Pages: 648
Size: 8.50" wide x 11.00" long x 1.25" tall
Weight: 3.586
Language: English

Claude G. Wasterlain is Chief of the Department of Neurology at the West Los Angeles VA Medical Center and Distinguished Professor and Vice Chair of the Department of Neurology at UCLA.

David M. Treiman is Director of the Epilepsy Center at the Barrow Neurological Institute at St. Joseph's Hospital and Medical Center, Phoenix.

Foreword
Contributors
Status Epilepticus: History, Definition, Classification, And Epidemiology
Historical Overview
Definition and Classification of Status Epilepticus
Incidence and Causes of Status Epilepticus
Prognosis After a First Episode of Status Epilepticus
Epidemiology of Childhood Status Epilepticus
Status Epilepticus: Clinical Phenomenology
Generalized Convulsive Status Epilepticus
Simple and Complex Partial Status Epilepticus
Absence Status
The Two Faces of Electrographic Status Epilepticus: The Walking Wounded and the Ictally Comatose
Status Epilepticus in Infancy and Childhood
Nonconvulsive Status Eilepticus in Children: With Special Reference to Electrical Status Epilepticus During Slow-Wave Sleep
Status Epilepticus in the Neonate
Status Epilepticus: Biological Markers
Physiologic Responses to Status Epilepticus
Clinical Neuropathology in Convulsive Status Epilepticus
Neuron-Specific Enolase in Status Epilepticus
Brain Imaging in Status Epilepticus
Basic Mechanisms: Pathophysiology
Self-Sustaining Status Epilepticus
Pathophysiology of Seizure Circuitry in Status Epilepticus
Neuroanatomy of Status Epilepticus
Role of GABAA Receptors in Status Epilepticus
Physiologic Mechanisms of Inhibition and Status Epilepticus
Glutamate and Glutamate Receptors in Status Epilepticus
Metabotropic Receptors in Status Epilepticus
The Role of Adenosine in Status Epilepticus
Basic Mechanisms: Brain Damage
Excitotoxicity in Status Epilepticus
Seizure-Induced Damage in the Immature Brain: Overcoming the Burden of Proof
Metabolic and Circulatory Adaptations to Status Epilepticus in the Immature Brain
Excitotoxicity and Seizures in the Immature Brain
Age-Specific Mechanisms of Status Epilepticus
Developmental Differences in Seizure Susceptibility and Hippocampal Vulnerability: Molecular Correlates
Seizures and Neurotrophic Factor Expression
Behavioral Consequences of Status Epilepticus in the Immature Brain
Basic Mechanisms: Epileptogenesis
Late Consequences of Status Epilepticus
Epileptogenic Effects of Status Epilepticus
Hippocampal Reactive Synaptogenesis from Status Epilepticus
Therapeutic Principles
Neuroprotective Strategies in Status Epilepticus
Generalized Convulsive Status Epilepticus: Principles of Treatment
Therapeutic Attitudes and Therapeutic Algorithms
Approach to the Management of Neonatal Status Epilepticus
Management of Status Epilepticus in Infants and Children
Pharmacotherapy
Benzodiazepines for Initial Treatment of Status Epilepticus
Phenytoin in the Treatment of Status Epilepticus
Phenytoin and Fosphenytoin
Phenobarbital in the Treatment of Status Epilepticus
Valproate
Other Pharmacologic Therapy for Refractory Status Epilepticus
Therapeutic Management
Approaches to Treating Status Epilepticus Outside the Hospital
The Treatment of Status Epilepticus Patients in the Emergency Setting
Critical Care of the Status Epilepticus Patient
The Impact of Status Epilepticus on Health Care Delivery Systems: Quality of Care and Access
Status Epilepticus: The Future
Index