Oligonucleotides and Analogues A Practical Approach

Name: Oligonucleotides and Analogues A Practical Approach
Price: 19.34 USD
Availability: InStock
ISBN: 9780199632794

ISBN-10: 0199632790

ISBN-13: 9780199632794

Edition: 1991

Authors: Fritz Eckstein

List price: $116.00

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Interest in oligonucleotide synthesis has expanded dramatically since the publication of M. Gait's book in this series in 1984. The process has been automated, new reagents have been developed, and the range of uses for the compounds produced has increased and continues to grow. This volume provides practical guidance on oligonucleotide synthesis and methods for introducing modifications into these molecules. State- of-the-art techniques for automated synthesis are covered in two chapters on the production of oligodeoxynucleotides and oligoribonucleotides. Synthesis of modified oligodeoxynucleotides is also detailed, including modification of the phosphate backbone to produce…

Book details

List price: $116.00
Copyright year: 1991
Publisher: Oxford University Press
Publication date: 1/16/1992
Binding: Paperback
Pages: 340
Size: 6.19" wide x 9.25" long x 0.72" tall
Weight: 1.298
Language: English




Modern Machine-Aided Methods of Oligodeoxyribonucleotide Synthesis




Oligoribonucleotide Synthesis




2'-O-Methyl Oligoribonucleotides




Phosphorothioate Oligonucleotides




Methylphosphonate Oligonucleotides




Oligonucleotides with Modified Bases




Oligonucleotides with Reporter Groups Attached to the 5' Terminus




Oligodeoxynucleotides with Reporter Groups Attached Via the Phosphate Backbone




Oligonucleotides for Affinity Chromatography




Oligonucleotides with Reporter Groups Attached Via the Base