Science of Marijuana

ISBN-10: 0195328248
ISBN-13: 9780195328240
Edition: 2nd 2008
List price: $36.95 Buy it from $22.31
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Book details

List price: $36.95
Edition: 2nd
Copyright year: 2008
Publisher: Oxford University Press, Incorporated
Publication date: 12/7/2007
Binding: Paperback
Pages: 352
Size: 5.50" wide x 8.50" long x 0.75" tall
Weight: 0.726
Language: English

Foreword
Introduction
The Plant
Consumption of Cannabis: Preparations for Their Psychoactive Effects
Smoking
Eating and Drinking
A Brief History
The Pharmacology of Delta-9-Tetrahydrocannabinol (THC), The Psychoactive Ingredient in Cannabis
Man-Made Cannabinoids
Cannabinoid Antagonists
How Does THC Get to the Brain?
Smoking
Oral Absorption
Other Routes of Administration
Elimination of THC From the Body
How Does THC Work?
Discovery of Cannabinoid Receptors
Neuroanatomical Distribution of CB-1 Receptors in the Brain
Some Physiological Effects of THC
Inhibition of Neurotransmitter Release
Effects on the Heart and Blood Vessels
Effects on Pain Sensitivity
Effects on Motility and Posture
The Billy Martin Tetrad
Endocannabinoids
Discovery of Naturally Occurring Endocannabinoids-The Endocannabinoids
Biosynthesis and Inactivation of Endocannabinoids
Physiological Functions of Endocannabinoids
Retrograde Signal Molecules at Synapses
Control of Energy Metabolism and Body Weight
Regulation of Pain Sensitivity
Cardiovascular Control
Other Functions
Development of a New Endocannabinoid-Based Pharmacology
Novel Cannabinoid Receptor Agonists or Antagonists
Inhibitors of Endocannabinoid Inactivation
The Effects of Cannabis on the Central Nervous System
Subjective Reports of the Marijuana High
Laboratory Studies of Marijuana in Human Volunteers
Effects on Movement and Driving
Higher Brain Function, Including Learning and Memory
Comparisons of Marijuana With Alcohol
What Can Animal Behavior Experiments Tell Us?
Does Repeated Use of Marijuana Lead to Tolerance and Dependence?
Medical Uses of Marijuana-Fact or Fantasy?
Historical
The Modern Revival of Interest in Cannabis-Based Medicines
The Synthetic Cannabinoids
Dronabinol (Marinol)
Nabilone (Cesamet)
Medical Targets for Cannabis
Multiple Sclerosis
Pain
Nausea and Vomiting Associated With Cancer Chemotherapy
AIDS Wasting Syndrome
Other Potential Medical Targets
Epilepsy
Bronchial Asthma
Moods Disorders and Sleep
Cancer
Diarrhea
Emerging Indications
Is There Any Role for Smoked Marijuana as a Medicine?
A Cannabinoid Antagonist for the Treatment of Obesity
Preclinical Data
Clinical Data
Conclusions
Is Cannabis Safe?
Toxicity
Acute Effects of Cannabis
Effects of Long-Term Exposure to Cannabis
Are There Persistent Cognitive Deficits?
Tolerance and Dependence
Adverse Effects on Fertility and the Unborn Child
Suppression of Immune System Function
Cannabis and Mental Illness
Special Hazards of Smoked Marijuana
Marijuana Smoke and Smoking Behavior
Effects of Marijuana Smoke on the Lungs
Marijuana Smoking and Lung Cancer
Summary
The Recreational Use of Cannabis
Prevalence
How Is Cannabis Consumed and Where Does It Come From?
Patterns of Recreational Use
What Are the Effects of Recreational Cannabis Use?
The Potency of Illicit Marijuana
Is Marijuana a Gateway Drug?
Do Recreational Marijuana Users Become Dependent?
Forensic Testing for Cannabis-Growth Industry
Snapshots of Cannabis Use Around the World
India and Pakistan
Nepal and Tibet
Southeast Asia
Africa
Caribbean and Latin America
Conclusions
What Next? A Hundred Years of Cannabis Reports
A Hundred Years of Cannabis Inquiries
The Indian Hemp Drugs Commission Report (1894)
Mayor La Guardia's Report, The Marihuana Problem in the City of New York (1944)
The Wooton Report, England (1969)
Report Followed Report
The Dutch Experiment
What Next? Is There a Case for the Legalization/Decriminalization/Depenalization of Cannabis?
References
Index

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