Handbook on Drug and Alcohol Abuse The Biomedical Aspects

ISBN-10: 0195172795

ISBN-13: 9780195172799

Edition: 4th 2004 (Revised)

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Description: This comprehensive text on the pharmacological, medical and legal aspects of drug abuse has been thoroughly updated, and a new chapter on club drugs added. The chapter on medical effects has been completely rewritten to focus on infections that develop in IV drug abusers, and the chapter on drug abuse and the law now extends to the international regulation of drug use. All major drugs of abuse are covered. For each type the authors discuss history and culture, patterns of use,subjective and physiological effects, mechanisms of pharmacological action, and toxic effects. Epidemiological aspects are discussed as well as pharmacological treatment possibilities where applicable.

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Book details

List price: $41.95
Edition: 4th
Copyright year: 2004
Publisher: Oxford University Press, Incorporated
Publication date: 6/3/2004
Binding: Paperback
Pages: 208
Size: 6.00" wide x 9.00" long x 0.50" tall
Weight: 0.748
Language: English

Introduction
Some Definitions
The Problem of Drug Abuse
Patterns and Development of Drug Use
Predictors of Initiation of Drug Abuse
Correlates of Cessation of Drug Use
Neurological Aspects of Drug Abuse
Tobacco and Nicotine
Tobacco Culture
Epidemiology and Patterns of Use
Pharmacokinetics and Pharmacodynamics
Effects of Nicotine
Subjective Effects
Physiological Dependence and Tolerance
Physiological Effects
Mechanism of Central Action
Morbidity and Mortality
Coronary Heart Disease
Cancer
Chronic Obstructive Pulmonary Disease
Smoking and Fetal Development
Passive Smoking
Treatment of Nicotine Addiction
Opioids
Culture and History
Opioid Drugs
Patterns of Use
Effects of Opioid Drugs
Subjective Effects
Analgesia
Gastrointestinal System
Respiration
In Utero Effects
Physiological Dependence
Tolerance
Mechanism of Action
Absorption and Fate
Toxicity
Pharmacological Treatment of Abuse
Depressants of the Central Nervous System: Alcohol, Barbiturates, and Benzodiazepines
Alcohol
Epidemiology and Patterns of Use
Genetics and Alcoholism
Central Nervous System Effects of Alcohol
Absorption, Distribution, and Metabolism
In Utero Effects of Alcohol
Beneficial Effects of Alcohol
Morbidity
Mortality
Pharmacological Treatment of Alcholism
Barbiturate and Nonbarbiturate Sedative-Hypnotics
Benzodiazepines and other Minor Tranquilizers
Effects of Benzodiazepines
Patterns of Use
Mechanism of Action
Tolerance and Physiological Dependence
Other Minor Tranquilizers
Depressants of the Central Nervous System: Volatile Solvents and Aerosols
Preparation Used
Patterns of Use
Effects of Volatile Solvents
Habitual Use of Volatile Solvents
Physiological Dependence
Toxic Effects of Volatile Solvents: Morbidity and Mortality
Aliphatic Hydrocarbons
Aromatic Hydrocarbons
Halogenated Hydrocarbons (Alkyl Halides)
Ketones
Esters
Nitrites
Club Drugs: Methylenedioxymethamphetamine (MDMA), Gamma Hydroxybutyrate (GHB), Ketamine, and Agents Taken in Similar Patterns
Methylenedioxymethamphetamine
Chemistry and Mechanism of Action
Effects and Toxicity
Patterns of Use
Metabolism
Gamma Hydroxybutyrate
Effects and Phamacokinetics
Dependence and Withdrawal
Medical Indications
Hallucinogens
Ketamine and Phencyclidine
Lysergic Acid Diethylamide
Marijuana and Hashish
Epidemiology and Patterns of Use
Pharmacokinetics and Pharmacodynamics
Physiological Dependence and Tolerance
Effects of Marijuana
Subjective Effects
Physiological Effects
Mechanism of Central Action
Adverse Effects
Acute Adverse Effects
Persistent Adverse Effects
Medical Use
Central Nervous System Stimulants: Cocaine, Amphetamines, Related Drugs, and Caffeine
Cocaine
Mechanism of Action, Absorption, and Fate
Toxicity
The Amphetamines
Neurotoxicity
Mechanism of Action, Absorption, and Fate
Effects of Amphetamine and Cocaine
Patterns of Use
Physiological Dependence on Stimulants
Khat Chewing and Cathinone
Caffeine and Theophylline
Patterns of Use
Effects
Physiological Dependence
Drugs Used to Treat Hyperactivity and Obesity
Medical Issues Associated with Drug Abuse
Infections Resulting from Intravenous Drug Use
Heart
Lung
Central Nervous System
Liver
Skin and Soft Tissue
Bone and Joint
Immune System
Pulmonary Health Risks from Smoking Illicit Drugs
Marijuana
Cocaine
Drug Abuse and the Law
Drug Abuse and American Federal Law
Drug Abuse and International Law
Index
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