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Biomedical Optical Imaging

ISBN-10: 0195150449
ISBN-13: 9780195150445
Edition: 2009
List price: $105.00
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Description: Biomedical optical imaging is a rapidly emerging research area with widespread fundamental research and clinical applications. This book gives an overview of biomedical optical imaging with contributions from leading international research groups  More...

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Book details

List price: $105.00
Copyright year: 2009
Publisher: Oxford University Press, Incorporated
Publication date: 4/22/2009
Binding: Hardcover
Pages: 416
Size: 7.25" wide x 10.25" long x 1.25" tall
Weight: 3.278
Language: English

Biomedical optical imaging is a rapidly emerging research area with widespread fundamental research and clinical applications. This book gives an overview of biomedical optical imaging with contributions from leading international research groups who have pioneered many of these techniques andapplications. A unique research field spanning the microscopic to the macroscopic, biomedical optical imaging allows both structural and functional imaging. Techniques such as confocal and multiphoton microscopy provide cellular level resolution imaging in biological systems. The integration of this technologywith exogenous chromophores can selectively enhance contrast for molecular targets as well as supply functional information on processes such as nerve transduction. Novel techniques integrate microscopy with state-of-the-art optics technology, and these include spectral imaging, two photon fluorescence correlation, nonlinear nanoscopy; optical coherence tomography techniques allow functional, dynamic, nanoscale, and cross-sectional visualization. Moving to themacroscopic scale, spectroscopic assessment and imaging methods such as fluorescence and light scattering can provide diagnostics of tissue pathology including neoplastic changes. Techniques using light diffusion and photon migration are a means to explore processes which occur deep insidebiological tissues and organs. The integration of these techniques with exogenous probes enables molecular specific sensitivity.

Contributors
Confocal Microscopy
Spectral Optical Imaging in Biology and Medicine
Multiphoton Microscopy in Neuroscience
Messenger RNA Imaging in Living Cells for Biomedical Research
Building New Fluorescent Probes
Imaging Membrane Potential with Voltage-Sensitive Dyes
Biomedical Imaging Using Optical Coherence Tomography
Two-Photon Fluorescence Correlation Spectroscopy
Nanoscopy: The Future of Optical Microscopy
Fluorescence Imaging in Medical Diagnostics
Flurescence and Spectroscopic Markers of Cervical Neoplasia
Quantitative Absorption and Scattering Spectra in Thick Tissues Using Broadband Diffuse Optical Spectroscopy
Detection of Brain Activity by Near-Infrared Light
In Vivo Optical Imaging of Molecular Function Using Near-Infrared Fluorescent Probes
Revealing the Subtleties of Disease and the Nuances of the Therapeutic Response with Optical Reporter Genes
Index

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