| |
| |
| Foreword | |
| |
| |
| |
| Contributors | |
| |
| |
| |
| Psychiatric Epidemiology, Then and Now | |
| |
| |
| |
| The Burden of Mental Illness | |
| |
| |
| |
| The Arc of Epidemiology | |
| |
| |
| |
| Searching for the Causes of Mental Disorders | |
| |
| |
| |
| Risk Factors as Causes of Mental Disorders | |
| |
| |
| |
| What Is a Cause? | |
| |
| |
| |
| Detecting Causes | |
| |
| |
| |
| Study Designs | |
| |
| |
| |
| Relationships among Causes | |
| |
| |
| |
| Measures of Association | |
| |
| |
| |
| Cohort Designs in Psychiatric Epidemiology | |
| |
| |
| |
| Prototypical Cohort Study | |
| |
| |
| |
| Diversity of Cohort Studies | |
| |
| |
| |
| Causal Inference: A Thought Experiment | |
| |
| |
| |
| Confounding: What It Is and What Can Be Done | |
| |
| |
| |
| Unequal Attrition under Different Types of Follow-Up | |
| |
| |
| |
| Differential Misclassification | |
| |
| |
| |
| Case-Control Designs in Psychiatric Epidemiology | |
| |
| |
| |
| Logic of the Case-Control Design | |
| |
| |
| |
| Applications of the Case-Control Study | |
| |
| |
| |
| Choosing Controls | |
| |
| |
| |
| Comparability and the Case-Control Study | |
| |
| |
| |
| Case-Control Designs in Biologic Psychiatry | |
| |
| |
| |
| Biologic Studies in Psychiatry | |
| |
| |
| |
| Choosing Cases in Biologic Psychiatry | |
| |
| |
| |
| Choosing Controls in Biologic Psychiatry | |
| |
| |
| |
| Analyzing the Data | |
| |
| |
| |
| Gauging the Precision of Measures of Association | |
| |
| |
| |
| Using Significance Tests in Establishing Associations | |
| |
| |
| |
| Planning Studies: Estimating Power and Sample Size | |
| |
| |
| |
| Adjustment for Covariates | |
| |
| |
| |
| Event Time Analysis | |
| |
| |
| |
| Assessing Heterogeneity of Effects | |
| |
| |
| |
| The Search for Genetic Causes of Mental Disorders | |
| |
| |
| |
| Integrating Epidemiology with Genetics | |
| |
| |
| |
| Genetic Association Studies | |
| |
| |
| |
| Modern Family History Studies | |
| |
| |
| |
| Twin Studies of Heritability | |
| |
| |
| |
| Genetic Linkage Studies | |
| |
| |
| |
| Designs for the Genomic Era | |
| |
| |
| |
| Complex Causal Relationships | |
| |
| |
| |
| Eco-Epidemiology | |
| |
| |
| |
| Causal Explanation within a Risk Factor Framework | |
| |
| |
| |
| Causal Explanation Outside the Black Box | |
| |
| |
| |
| Dependent and Dynamic Processes | |
| |
| |
| |
| Our Approach to Epidemiologic Concepts and Methods | |
| |
| |
| |
| Application of Survival Analysis to Prenatal Determinants of Schizophrenia Example (PDSE) Data | |
| |
| |
| Glossary | |
| |
| |
| Index | |