Hyperglycemia, Diabetes and Vascular Disease

Name: Hyperglycemia, Diabetes and Vascular Disease
Price: 14.13 USD
Availability: InStock
ISBN: 9780195067736

ISBN-10: 0195067738

ISBN-13: 9780195067736

Edition: 1992

Authors: Neil Ruderman, Joseph R. Williamson, Michael Brownlee

List price: $96.00

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There are over 12 million people with diabetes in the U.S. Blindness, renal failure, and coronary heart disease are the three most frequent complications of late-stage diabetes, and diabetic patients are at greater risk for developing these conditions than the rest of the population. This book examines the link between hyperglycemia and micro- and macro- vascular disease in diabetes. The authors review clinical, epidemiological, and biochemical evidence that high levels of blood glucose produce metabolic and biochemical alterations in vascular walls. These alterations in turn lead to abnormalities in vascular structure and, ultimately, function. Although there are differences in the…

Book details

List price: $96.00
Copyright year: 1992
Publisher: Oxford University Press, Incorporated
Publication date: 10/1/1992
Binding: Hardcover
Pages: 320
Size: 7.00" wide x 10.50" long x 0.75" tall
Weight: 2.134
Language: English




Epidemiology and Physiology



Hyperglycemia, Diabetes and Vascular Disease: An Overview




Epidemiology of Hyperglycemia and Atherosclerosis




Altered Platelet Function in Diabetes Mellitus: Effect of Glycemic Regulation and Antiplatelet Agents




Diabetes Mellitus and the Vascular Endothelin




Cerebral Microvascular Transport and Metabolism: Implications for Diabetes




Polyols, Myoinositol and Signal Transduction



Mechanisms of Glucose and Diabetes-Induced Vascular Dysfunction




Mechanisms of Early Hyperglycemia-Induced Alterations in Vascular Metabolism and Autoregulation




Dissociation of Retinopathy and Nephropathy in Animal Models of Diabetes: Diabetes vs. Galactosemia




Cell Culture Model for the Study of Vascular Complications of Diabetes: The Effect of High Glucose Levels on Metabolism and Growth of Vascular Cells




Mobilization of Arachidonic Acid from Diacyl and Ether Phospholipids in Cultured Endothelial Cells




Protein Glycates and Glycosoaminoglycans



Glycation and Autoxidation of Proteins in Aging and Diabetes




Nonenzymatic Glycosylation of Macromolecules: Prospects for Pharmacologic Modulation




Cell Mediated Interactions of Advanced Glycosylation Endproducts and the Vascular Wall




Effects on Nonenzymatic Glycation on Molecular Interactions of Basement Membrane Molecules




The Effects of Diabetes on Kidney Proteoglycans