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Epigenetics in Health and Disease

ISBN-10: 013259708X
ISBN-13: 9780132597081
Edition: 2012
List price: $61.99
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Description: This is the first comprehensive, authoritative, and easy-to-understand introduction to modern epigenetics. Authored by two active researchers in the field, it introduces key concepts one step at a time, enabling students at all levels to benefit  More...

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Book details

List price: $61.99
Copyright year: 2012
Publisher: Pearson Education, Limited
Publication date: 5/24/2012
Binding: Hardcover
Pages: 608
Size: 6.25" wide x 9.25" long x 1.50" tall
Weight: 2.310
Language: English

This is the first comprehensive, authoritative, and easy-to-understand introduction to modern epigenetics. Authored by two active researchers in the field, it introduces key concepts one step at a time, enabling students at all levels to benefit from it. the authors begin by presenting a historical overview that places epigenetics in context, and makes it clear that the field is not (as some presume) completely new. Next, they introduce and explain key epigenetic mechanisms, and discuss the roles these mechanisms may play in inheritance, organism development, health and disease, behavior, evolution, ecology, and the interaction of individual organisms with their environments. Coverage includes: non-coding RNAs in each kingdom; allelic interactions; CRYSPR; gene silencing; epigenetics of germline and epigenetic memory; epigenetic regulation of genome stability and plant stress response; and much more. the authors conclude by offering significant new insights into how knowledge of epigenetics and epigenomics may promote the development of technologies and solutions in areas ranging from behavioral neuroscience to cancer treatment, toxicology to the development of hardier crops.

Historical Perspective
Chromatin Dynamics and Chromatin Remodeling in Animals
Chromatin Dynamics and Chromatin Remodeling in Plants
DNA Methylation as Epigenetic Mechanism
Histone Modifications and Their Role in Epigenetic Regulation
Realm of Non-Coding RNAs-From Bacteria to Human
Non-Coding RNAs Involved in Epigenetic Processes-A General Overview
Non-Coding RNAs Across the Kingdoms-Bacteria and Archaea
Non-Coding RNAs Across the Kingdoms-Protista and Fungi
Non-Coding RNAs Across the Kingdoms-Animals
Non-Coding RNAs Across the Kingdoms-Plants
Non-Coding RNAs-Comparison of Biogenesis in Plants and Animals
Paramutation, Transactivation, Transvection, and Cosuppression-Silencing of Homologous Sequences
Bacterial Adaptive Immunity-Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)
Gene Silencing-Ancient Immune Response and a Versatile Mechanism of Control over the Fate of Foreign Nucleic Acids
Epigenetics of Germline and Epigenetic Memory
Epigenetics of Health and Disease-Cancer
Epigenetics of Health and Disease-Behavioral Neuroscience
Epigenetics of Health and Disease-Diet and Toxicology, Environmental Exposures
Epigenetics and Technology-Hairpin-Based Antisensing
Index

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