Biomaterials Science An Introduction to Materials in Medicine

ISBN-10: 0125824637
ISBN-13: 9780125824637
Edition: 2nd 2004 (Revised)
List price: $119.00
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Description: The contributors to this volume highlight the science and engineering fundamentals behind biomaterials and their applications and contains sufficient background material to guide the reader to a complete appreciation of the field of biomaterials.

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Book details

List price: $119.00
Edition: 2nd
Copyright year: 2004
Publisher: Elsevier Science & Technology Books
Publication date: 7/30/2004
Binding: Hardcover
Pages: 864
Size: 8.50" wide x 11.00" long x 1.75" tall
Weight: 5.632
Language: English

The contributors to this volume highlight the science and engineering fundamentals behind biomaterials and their applications and contains sufficient background material to guide the reader to a complete appreciation of the field of biomaterials.

Buddy D. Ratner, Michael L. and Myrna Darland Endowed Chair in Bioengineering and Professor of Chemical Engineering at the University of Washington, received his Ph.D. (1972) in polymer chemistry from the Polytechnic Institute of Brooklyn. From 1985-1996 he directed the NIH-funded National ESCA and Surface Analysis Center for Biomedical Problems (NESAC/BIO), and in 1996 he assumed the directorship of University of Washington Engineered Biomaterials (UWEB), an NSF Engineering Research Center. He is the editor of the Journal of Undergraduate Research in Bioengineering, a past president of the Society for Biomaterials and author of 400 scholarly works. Ratner is a fellow of the American Institute of Medical and Biological Engineering (AIMBE), the American Vacuum Society and a Fellow, Biomaterials Science and Engineering (FBSE). He served as president of AIMBE, 2002-2003. He is vice president of the Tissue Engineering Society International (TESI) 2003-2005. In 2002 Ratner was elected a member of the National Academy of Engineering, USA, and in 2004 he won the Founder's Award for the Society For Biomaterials. His research interests include biomaterials, tissue engineering, polymers, biocompatibility, surface analysis of organic materials, self-assembly, nanobiotechnology and RF-plasma thin film deposition. Summary of Buddy Ratner's awards and honors: 1989 Clemson Award for Contributions to the Biomaterials Literature 1990 Burlington Resources Foundation Faculty Achievement Award for Outstanding Research 1991 Perkin-Elmer Physical Electronics Award for Excellence in Surface Science 1991-1992 President, Society For Biomaterials 1993 Founding Fellow, American Institute of Medical and Biological Engineering (AIMBE) 1993 Fellow, American Vacuum Society; Vice President, AIMBE 1993 Fellow, Society For Biomaterials; Van Ness Lecturer, Rensselaer Polytechnic Institute 1998 C.M.A. Stine Award in Materials Science (AIChE); American Vacuu

Professor Hoffman studied at M.I.T., where he received B.S., M.S., and Sc.D. degrees in Chemical Engineering between 1953 and 1957. He taught on the faculty of M.I.T. Chemical Engineering Department for a total of ten years. He also spent four years in industry. Since 1970 he has been Professor of Bioengineering at the University of Washington in Seattle, Washington. Professor Hoffman has over 330 publications, several books and chapters, 21 patents and several other patents pending. He is on the Editorial Boards of seven scientific journals. Summary of professional activities and awards include: .President, Society for Biomaterials, 1983-1984 .Clemson Award in Biomaterials, 1984 .Board of Governors, Controlled Release Society, 1991-1994 .Biomaterials Science Prize, Japanese Biomaterials Society, 1990 .Founders' Award of the Society for Biomaterials, 2000 .Election to the National Academy of Engineering, 2005 In December, 1992, Hoffman's colleagues organized a symposium in Maui, Hawaii in honor of his 60th birthday. In December, 2002 his 70th birthday was celebrated at another special symposium, once again in Maui, Hawaii. Papers from the first symposium were published in the Journal of Biomaterials Science (Polymer Edition), along with a Festschrift book, and similar publications are in press at this time from the second symposium.

Editors and Lead Contributors
Preface
Biomaterials Science: A Multidisciplinary Endeavor
A History of Biomaterials
Materials Science and Engineering
Properties of Materials
Introduction
Bulk Properties of Materials
Finite Element Analysis
Surface Properties and Surface Characterization of Materials
Role of Water in Biomaterials
Classes of Materials Used in Medicine
Introduction
Polymers
Silicone Biomaterials: History and Chemistry
Medical Fibers and Biotextiles
Hydrogels
Applications of "Smart Polymers" as Biomaterials
Bioresorbable and Bioerodible Materials
Natural Materials
Metals
Ceramics, Glasses, and Glass-Ceramics
Pyrolytic Carbon for Long-Term Medical Implants
Composites
Nonfouling Surfaces
Physicochemical Surface Modification of Materials Used in Medicine
Textured and Porous Materials
Surface-Immobilized Biomolecules
Biology, Biochemistry, and Medicine
Some Background Concepts
Background Concepts
The Role of Adsorbed Proteins in Tissue Response to Biomaterials
Cells and Cell Injury
Tissues, the Extracellular Matrix, and Cell-Biomaterial Interactions
Mechanical Forces on Cells
Host Reactions to Biomaterials and Their Evaluation
Introduction
Inflammation, Wound Healing, and the Foreign-Body Response
Innate and Adaptive Immunity: The Immune Response to Foreign Materials
The Complement System
Systemic Toxicity and Hypersensitivity
Blood Coagulation and Blood-Materials Interactions
Tumorigenesis and Biomaterials
Biofilms, Biomaterials, and Device-Related Infections
Biological Testing of Biomaterials
Introduction to Testing Biomaterials
In Vitro Assessment of Tissue Compatibility
In Vivo Assessment of Tissue Compatibility
Evaluation of Blood-Materials Interactions
Large Animal Models in Cardiac and Vascular Biomaterials Research and Testing
Microscopy for Biomaterials Science
Degradation of Materials in the Biological Environment
Introduction: Degradation of Materials in the Biological Environment
Chemical and Biochemical Degradation of Polymers
Degradative Effects of the Biological Environment on Metals and Ceramics
Pathological Calcification of Biomaterials
Application of Materials in Medicine, Biology, and Artificial Organs
Introduction
Nonthrombogenic Treatments and Strategies
Cardiovascular Medical Devices
Implantable Cardiac Assist Devices
Artificial Red Blood Cell Substitutes
Extracorporeal Artificial Organs
Orthopedic Applications
Dental Implantation
Adhesives and Sealants
Ophthalmological Applications
Intraocular Lens Implants: A Scientific Perspective
Burn Dressings and Skin Substitutes
Sutures
Drug Delivery Systems
Bioelectrodes
Cochlear Prostheses
Biomedical Sensors and Biosensors
Diagnostics and Biomaterials
Medical Applications of Silicones
Tissue Engineering
Introduction
Overview of Tissue Engineering
Immunoisolation
Synthetic Bioresorbable Polymer Scaffolds
Practical Aspects of Biomaterials
Implants, Devices, and Biomaterials: Issues Unique to this Field
Introduction
Sterilization of Implants and Devices
Implant and Device Failure
Correlation, Surfaces and Biomaterials Science
Implant Retrieval and Evaluation
New Products and Standards
Introduction
Voluntary Consensus Standards
Development and Regulation of Medical Products Using Biomaterials
Ethical Issues in the Development of New Biomaterials
Legal Aspects of Biomaterials
Perspectives and Possibilities in Biomaterials Science
Properties of Biological Fluids
Properties of Soft Materials
Chemical Compositions of Metals Used for Implants
The Biomaterials Literature
Index

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