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Principles of Molecular Virology

ISBN-10: 012384939X
ISBN-13: 9780123849397
Edition: 5th 2012
Authors: Alan J. Cann
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Book details

List price: $69.95
Edition: 5th
Copyright year: 2012
Publisher: Elsevier Science & Technology Books
Publication date: 9/2/2011
Binding: Paperback
Pages: 320
Size: 7.25" wide x 9.00" long x 0.75" tall
Weight: 1.166
Language: English

Alan Cann has worked in both the U.K. and U.S.A., and in addition to teaching undergraduate, postgraduate, and medical students, he runs a research laboratory studying themolecular biology and pathogenesis of RNA viruses.

Introduction
Viruses are Distinct from Living Organisms
The History of Virology
Living Host Systems
Cell Culture Methods
Serological/Immunological Methods
Ultrastructural Studies
'Molecular Biology'
Further Reading
Particles
The Function and Formation of Virus Particles
Capsid Symmetry and Virus Architecture
Helical capsids
Icosahedral (isometric) capsids
Enveloped Viruses
Complex Virus Structures
Protein-Nucleic Acid Interactions and Genome Packaging
Virus Receptors - Recognition and Binding
Other Interactions of the Virus Capsid with the Host Cell
Summary
Further Reading
Genomes
The Structure and Complexity of Virus Genomes
Molecular Genetics
Virus Genetics
Virus Mutants
Types of mutant virus
Suppression
Genetic Interactions between Viruses
Non-genetic Interactions between Viruses
'Large' DNA Genomes
'Small' DNA Genomes
Positive-Strand RNA Viruses
Negative-Strand RNA Viruses
Segmented and MultiPartite Virus Genomes
Reverse Transcription and Transposition
Evolution and Epidemiology
Summary
Further Reading
Replication
Overview of Virus Replication
Investigation of Virus Replication
The Replication Cycle
Summary
Further Reading
Expression
Expression of Genetic Information
Control of Prokaryote Gene Expression
Control of Expression in Bacteriophage �
Control of Eukaryote Gene Expression
Genome Coding Strategies
Transcriptional Control of Expression
Post-Transcriptional Control of Expression
Summary
Further Reading
Infection
Virus Infections of Plants
Immune Responses to Virus Infections in Animals
Virus-Host Interactions
The Course of Virus Infections
Prevention and Therapy of Virus Infection
Virus Vectors and Gene Therapy
Chemotherapy of Virus Infections
Summary
Further Reading
Pathogenesis
Mechanisms of Cellular Injury
Viruses and Immunodeficiency
Virus-Related Diseases
Bacteriophages and Human Disease
Cell Transformation by Viruses
Viruses and Cancer
New and Emergent Viruses
Zoonoses
Bioterrorism
Summary
Further Reading
Subviral Agents: Genomes Without Viruses, Viruses Without Genomes
Satellites and Viroids
Prions
Summary
Further Reading
Glossary and Abbreviations
Classification of Subcellular Infectious Agents
The History of Virology
Index

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