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Basis of Disease Pathogenesis | |
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Genetics | |
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Major histocompatibility complex class II | |
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Genetic susceptibility and class III complement genes | |
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Constitutive genes and lupus | |
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Genetics of lupus in mice | |
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Tolerance and autoimmunity | |
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Dendritic cells in SLE | |
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T cells and systemic lupus erthematosus | |
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B-lymphocyte biology in SLE | |
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Polymorhonuclear and endothelial cells | |
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Mechanisms and consequences of mitochondrial dysfunction and oxidative stress in T cells of patients with SLE | |
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Cell cycle regulation and systemic lupus erythematosus | |
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The role of reactive nitrogen and oxygen intermediates in systemic lupus erythematosus | |
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Origins of antinuclear antibodies | |
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Anti-DNA antibodies: Structure, regulation and pathogenicity | |
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Extractable nuclear antigens and SLE: specificity and role in disease pathogenesis | |
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Antihistone and antispliceosomal antibodies | |
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Toll-like receptors in SLE | |
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Interferon-alpha in systemic lupus erythematosus | |
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Immune complexes in systemic lupus erythematosus | |
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Complement and tissue injury in SLE | |
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Humoral pathogenesis: Fc receptors in autoimmunity and end-organ damage | |
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Environmental Aspects of Pathogenesis | |
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Drug-induced lupus mechanisms | |
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Gender and age in lupus | |
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Roles for infections in systemic lupus erythematosus pathogenesis | |
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Systemic lupus erythematosus in domestic animals | |
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Mechanisms of Tissue Injury | |
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Pathogenesis of lupus nephritis | |
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Tissue injury and the skin | |
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Neuropsychiatric systemic lupus erythematosus: Mechanisms of injury | |
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Atherosclerosis and tissue injury in systemic lupus erythematosus | |
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Clinical Aspects of Disease | |
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Clinical Presentation | |
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The clinical presentation of systemic lupus erythematosus | |
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Neonatal lupus | |
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SLE in children | |
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Drug-induced disease | |
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Laboratory evaluation of patients with systemic lupus erythematosus | |
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Pregnancy and reproductive concerns in systemic lupus erythematosus | |
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Epidemiology of systemic lupus erythematosus | |
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Monitoring disease activity | |
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Incomplete lupus erythematosus | |
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Design of clinical trials for SLE | |
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Organ Systems | |
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The nervous system and lupus | |
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Skin | |
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Kidney | |
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Heart | |
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Vasculitis | |
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Lung | |
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Gastrointestinal: Liver | |
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Gastrointestinal: Nonhepatic | |
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Cellular hematology | |
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Musculoskeletal system: Articular disease, bone metabolism | |
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Anti-Phospholipid Syndrome | |
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Pathogenesis | |
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Antiphospholipid antibody: Pathogenesis | |
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Endothelial cell damage and atherosclerosis | |
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Clinical | |
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Laboratory testing for antiphospholipid syndrome | |
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Clinical presentation of antiphospholipid syndrome | |
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Pregnancy and antiphospholipid syndrome | |
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Treatment of antiphospholipid syndrome | |
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Treatment | |
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Steroids and nonsteroidal anti-inflammatory drugs | |
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Antimalarials | |
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Cytotoxic agents | |
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Biological agents | |
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