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Contributors | |
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Preface | |
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Neuroimmune Relationships in Perspective | |
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Introduction | |
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Innate and Acquired Immunity | |
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The Neuroendocrine System and the Balance of the Immune System | |
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Conclusions | |
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Sympathetic Nervous System Interaction with the Immune System | |
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Introduction | |
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Anatomy and Physiology | |
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Adrenergic Receptor Expression on Immune Cells | |
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Effect of [beta subscript 2]AR Stimulation on CD4[superscript +] T Lymphocytes | |
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Effect of [beta subscript 2] AR Stimulation on B Lymphocytes | |
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Conclusion | |
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References | |
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Mechanisms by Which Cytokines Signal the Brain | |
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Introduction | |
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Interleukin-1 (IL-1) | |
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Conclusions | |
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References | |
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Neuropeptides: Modulators of Immune Responses in Health and Disease | |
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Introduction | |
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CRH and Related Peptides | |
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Pro-opiomelanocortin (POMC) Peptides | |
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Opioid Peptides Other Than [beta]-Endorphin | |
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Trophic Peptides | |
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Other Immunoneuropeptides | |
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Quantitative Analysis of Immunoneuropeptides by MACS | |
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Conclusions | |
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References | |
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Brain-immune Interactions in Sleep | |
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Sleep | |
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Microbial Products and Cytokines: A Brief Overivew | |
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Effects of Microbial Products and Cytokines on Sleep | |
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Effect of Sleep-Wake Activity on Cytokines and the Immune System | |
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Summary | |
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References | |
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Neuroendocrinology of Autoimmunity | |
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Introduction | |
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The Hypothalamic-Pituitary-Adrenal (HPA) Axis | |
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The HPA Axis in Autoimmune Disease | |
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Neurotransmitters in Disease | |
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Summary | |
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References | |
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Systemic Stress-Induced Th2 Shift and Its Clinical Implications | |
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Introduction | |
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Th1/Th2 Paradigm: Role of Type 1 and Type 2 Cytokines | |
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Stress Hormones and Th1/Th2 Balance | |
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Clinical Implications | |
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Conclusions | |
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References | |
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Neural Control of Salivary S-IgA Secretion | |
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Introduction | |
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Nerve-Mediated Increases in Salivary Secretion of S-IgA | |
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Autonomimetic Stimulation of pIgR-Mediated IgA Transcytosis | |
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Studies of Reflex IgA Secretion | |
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Long-Term Influences of Nerves on S-IgA Secretion | |
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Effects of Nerves on Plasma Cell Production of IgA | |
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Conclusion | |
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References | |
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Stress and Secretory Immunity | |
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Introduction | |
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Saliva as a Model for Mucosal Secretory Defense | |
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An Outline of Secretory Immunity | |
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The Neurobiological Basis for Stress-Induced Changes in Salivary Secretory Immunity | |
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Stress and Secretory IgA | |
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Stress and Innate Secretory Immunity | |
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Stress and Microbial Colonization Processes | |
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Future Perspectives | |
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References | |
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Cytokines and Depression | |
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Introduction | |
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Depression and Immune System Dysregulation | |
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Neuroendocrine Dysregulation | |
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Relationship between Immune and Neuroendocrine System Changes | |
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Effect of Cytokines on Mood | |
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Role of Brain Monoamines | |
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Conclusions | |
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References | |
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Immunity and Schizophrenia: Autoimmunity, Cytokines, and Immune Responses | |
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Background | |
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Autoimmune Diseases and Schizophrenia | |
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T and B Lymphocytes in Schizophrenia | |
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HLA Antigens in Schizophrenia | |
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HPA Axis in Schizophrenia | |
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Effects of Antipsychotic Medication | |
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Treatment of Schizophrenia with Immunosuppressants | |
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Vaccine Response | |
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Th1/Th2 Imbalance in Schizophrenia | |
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Summary | |
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References | |
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Cerebral Lateralization and the Immune System | |
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Introduction | |
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Opposite Effects of Left- and Right-Cortical Ablations on Immunity | |
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Association between Behavioral Lateralization and Immune Reactivity | |
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General Conclusion and Perspectives | |
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References | |
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Behavioral Conditioning of the Immune System | |
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Introduction | |
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Conditioned Immunosuppression Using Cyclosporin A | |
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Conditioned Immunopotentiation | |
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Antigen as the Unconditioned Stimulus | |
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Human Studies | |
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Conclusion | |
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References | |
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Psychological and Neuroendocrine Correlates of Disease Progression | |
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Introduction | |
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Psychological Correlates Associated with Disease Progression | |
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Intervention Studies | |
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Neuroendocrine and Immunological Correlates That Underpin Disease Progression | |
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Neuroimmune Alterations Associated with Psychological Interventions | |
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Other Explanatory Mechanisms in Disease Progression | |
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References | |
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The Role of Psychological Intervention in Modulating Aspects of Immune Function in Relation to Health and Well-Being | |
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Introduction | |
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Relaxation Training | |
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Guided Imagery of the Immune System | |
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Hypnosis and Immunity | |
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Research Directions | |
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References | |
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Index | |
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Contents of Recent Volumes | |