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Contributors | |
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Preface | |
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Catecholamine Synthesis and Release | |
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Overview | |
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Regulation and Expression of Tyrosine Hydroxylase | |
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The Effect of Phosphorylation at Ser-40 on the Structure and Thermal Stability of Tyrosine Hydroxylase | |
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Factors Affecting Adrenal Medullary Catecholamine Biosynthesis and Release | |
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Regulation of Tyrosine Hydroxylase by Neuropeptides | |
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Regulation of Tyrosine Hydroxylase Gene Expression by Transsynaptic Mechanisms and Cell-Cell Contact | |
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A New Regulatory Protein of Catecholamine Synthesizing-Enzyme Expression | |
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Unique and Cell-Type-Specific Tyrosine Hydroxylase Gene Expression | |
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Triple Colocalization of Tyrosine Hydroxylase, Calretinin, and Calbindin D-28k in the Periventricular-Hypophyseal Dopaminergic Neuronal System | |
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Genetic Disorders Involving Recycling and Formation of Tetrahydrobiopterin | |
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Genetic Basis of Dominant Dystonia | |
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Mutations in the Tyrosine Hydroxylase Gene Cause Various Forms of L-Dopa-Responsive Dystonia | |
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Catecholamine Biosynthetic Enzyme Expression in Neurological and Psychiatric Disorders | |
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Other Catecholamine-Synthesizing Enzymes | |
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Multiple Pathways in Regulation of Dopamine [beta]-Hydroxylase | |
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Examining Adrenergic Roles in Development, Physiology, and Behavior through Targeted Disruption of the Mouse Dopamine [beta]-Hydroxylase Gene | |
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Genetic Diseases of Hypotension | |
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Dopamine [beta]-Hydroxylase Deficiency Associated with Mutations in a Copper Transporter Gene | |
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Glucocorticoid-Phenylethanolamine-N-methyltransferase Interactions in Humans | |
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Determinants of Phenylethanolamine-N-methyltransferase Expression | |
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Neural Control of Phenylethanolamine-N-methyltransferase via Cholinergic Activation of Egr-I | |
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Synexin (Annexin VII) Hypothesis for Ca[superscript 2+]/GTP-Regulated Exocytosis | |
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Monoamine Transmitter Release from Small Synaptic and Large Dense-Core Vesicles | |
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Calcium Channels for Exocytosis in Chromaffin Cells | |
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Characteristics of Transmitter Secretion from Individual Sympathetic Varicosities | |
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Neurotransmitter Release at Individual Sympathetic Varicosities, Boutons | |
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Appropriate Target Cells Are Required for Maturation of Neurotransmitter Release Function of Sympathetic Neurons in Culture | |
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Effects of Neuropeptide Y at Sympathetic Neuroeffector Junctions | |
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Strategies for Receptor Control of Neurotransmitter Release | |
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Pattern of Adenosine Triphosphate and Norepinephrine Release and Clearance: Consequences for Neurotransmission | |
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Corelease of Norepinephrine and Adenosine Triphosphate from Sympathetic Neurones | |
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Neuropeptide Y: An Adrenergic Cotransmitter, Vasoconstrictor, and a Nerve-Derived Vascular Growth Factor | |
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Neuropeptide Y: A Cardiac Sympathetic Cotransmitter? | |
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Biochemistry of Somatodendritic Dopamine Release in Substantia Nigra: An in Vivo Comparison with Striatal Dopamine Release | |
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The Use of Dual-Probe Microdialysis for the Study of Catecholamine Release in the Brain and Pineal Gland | |
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Kinetics and Geometry of the Excitatory Dopaminergic Transmission in the Rat Striatum in Vivo | |
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In Vivo and in Vitro Assessment of Dopamine Uptake and Release | |
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Catecholamine Reuptake and Storage | |
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Overview | |
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The Plasma Membrane Transporters | |
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Molecular Physiology and Regulation of Catecholamine Transporters | |
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Localization of Dopamine Transporter Protein by Microscopic Histochemistry | |
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Cellular and Subcellular Localization of the Dopamine Transporter in Rat Cortex | |
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Cloned Catecholamine Transporters Expressed in Polarized Epithelial Cells: Sorting, Drug Sensitivity, and lon-Coupling Stoichiometry | |
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Inactivation of the Dopamine Transporter Reveals Essential Roles of Dopamine in the Control of Locomotion, Psychostimulant Response, and Pituitary Function | |
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Role of Protein Kinase C and Second Messengers in Regulation of the Norepinephrine Transporter | |
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Electrophysiological Analysis of Transporter Function | |
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Voltammetric Approaches to Kinetics and Mechanism of the Norepinephrine Transporter | |
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Voltage-Dependency of the Dopamine Transporter in Rat Brain | |
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Modulation of Quantal Dopamine Release by Psychostimulants | |
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Regulation of Dopamine Transporter mRNA Levels in the Central Nervous System | |
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Structural Diversity in the Catecholamine Transporter Gene Family: Molecular Cloning and Characterization of an L-Epinephrine Transporter from Bullfrog Sympathetic Ganglia | |
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Positron Emission Tomography Radiogands for Dopamine Transporters and Studies in Human and Nonhuman Primates | |
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Single Photon Emission Computed Tomography Imaging of Dopaminergic Function: Presynaptic Transporter, Postsynaptic Receptor, and "Intrasynaptic" Transmitter | |
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Dopamine Transporter Changes in Neuropsychiatric Disorders | |
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Vesicular Transporters and Catecholamine Storage | |
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Molecular and Biochemical Studies of Rat Vesicular Monoamine Transporter | |
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A Chimeric Vesicular Monoamine Transporter Dissociates Senitivity to Tetrabenazine and Unsubstituted Aromatic Amines | |
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Ligand Recognition by the Vesicular Monoamine Transporters | |
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Molecular Pharmacology of the Vesicular Monoamine Transporter | |
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Ultrastructural Localization of the Vesicular Monoamine Transporter 2 in Mesolimbic and Nigrostriatal Dopaminergic Neurons | |
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ICA 512, Receptor Tyrosine Phosphatase-Like Protein, Is Concentrated in Neurosecretory Granule Membranes | |
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Protein Targeting in Neurons and Endocrine Cells | |
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The Vesicular Monoamine Transporter VMAT2 and Vesicular Acetylcholine Transporter VAChT Are Sorted to Separate Vesicle Populations in PC12 Cells | |
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Recycling of Synaptic Vesicles | |
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The Secretory Cocktail of Adrenergic Large Dense-Core Vesicles: The Functional Role of the Chromogranins | |
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A Novel, Catecholamine Release-Inhibitory Peptide from Chromogranin A: Autocrine Control of Nicotinic Cholinergic-Stimulated Exocytosis | |
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Transcription Regulation Coupled to Calcium and Protein Kinase Signaling Systems through TRE- and CRE-Like Sequences in Neuropeptide Genes | |
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Imaging of Monoaminergic and Cholinergic Vesicular Transporters in the Brain | |
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Catecholamine Metabolism: From Molecular Understanding to Clinical Diagnosis and Treatment | |
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Overview | |
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Monoamine Oxidase | |
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Monoamine Oxidase A and B: Structure, Function, and Behavior | |
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Genetic Deficiencies of Monoamine Oxidase Isoenzymes: A Key to Understanding the Function of the Enzymes in Humans | |
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Biological Markers, with Special Regard to Platelet Monoamine Oxidase (trbc-MAO), for Personality and Personality Disorders | |
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Visualization of Monoamine Oxidase in Human Brain | |
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Aliphatic N-Methylpropargylamines: Monoamine Oxidase-B Inhibitors and Antiapoptotic Drugs | |
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Antiapoptotic Actions of Monoamine Oxidase B Inhibitors | |
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Therapeutic Actions of L-Deprenyl in Dogs: A Model of Human Brain Aging | |
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Apomorphine Is a Potent Radical Scavenger and Protects Cultured Pheochromocytoma Cells from H[subscript 2]O[subscript 2]-Induced Cell Death | |
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O-Methylation and Conjugation | |
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Catechol O-Methyltransferase: Characterization of the Protein, Its Gene, and the Preclinical Pharmacology of COMT Inhibitors | |
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X-Ray Crystallography of Catechol O-Methyltransferase: Perspectives for Target-Based Drug Development | |
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Catechol O-Methyltransferase Inhibition and the Treatment of Parkinson's Disease | |
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The Structure and Function of the UDP-Glucuronosyltransferase Gene Family | |
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Catecholamine Sulfation in Health and Disease | |
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Metabolism of Endobiotics and Xenobiotics by UDP-Glucuronosyltransferase | |
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Catecholamine Metabolizing Systems | |
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Molecular Structure of the Carrier Responsible for Hepatic Uptake of Catecholamines | |
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Catecholamine Uptake and Metabolism in the Liver | |
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Catecholamine Uptake and Metabolism in Rat Lungs | |
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The Extraneuronal Monoamine Transporter Exists in Human Central Nervous System Glia | |
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Removal of Circulating Catecholamines by Extraneuronal Amine Transport Systems | |
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Catecholamine Metabolites in Internal Jugular Plasma: A Window into the Human Brain | |
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Norepinephrine Metabolites in Plasma as Indicators of Pharmacological Inhibition of Monoamine Oxidase and Catechol O-Methyltransferase | |
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The Adrenal Gland as a Source of Dihydroxyphenylalanine and Catecholamine Metabolites | |
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Clues to the Diagnosis of Pheochromocytoma from the Differential Tissue Metabolism of Catecholamines | |
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Catecholamine Receptors and Signal Transduction | |
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Overview | |
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Structure, Classification, and Tissue Localization of Catecholamine Receptor Subtypes | |
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Expression and Regulation of [alpha subscript 1]-Adrenergic Receptors in Human Tissues | |
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[alpha subscript 1]-Adrenoceptor Subtypes in the Human Cardiovascular and Urogenital Systems | |
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Molecular Mechanisms of Ligand Binding and Activation of [alpha subscript 1]-Adrenergic Receptors | |
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Expansion of the Dopamine D1 Receptor Gene Family: Defining Molecular, Pharmacological, and Functional Criteria for D1A, D1B, D1C, and D1D Receptors | |
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D1/D3 Receptor Relationships in Brain: Coexpression, Coactivation, and Coregulation | |
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Mapping the Binding-Site Crevice of the D2 Receptor | |
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Intracellular Mechanisms | |
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Mechanisms of [beta]-Adrenergic Receptor Desensitization and Resensitization | |
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Role of [beta]-Arrestins in the Intracellular Trafficking of G-Protein-Coupled Receptors | |
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G-Protein-Linked Receptors as Substrates for Tyrosine Kinases: Cross-Talk in Signaling | |
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Role of Arrestins in G-Protein-Coupled Receptor Endocytosis | |
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Subtype-Specific Regulation of the [beta]-Adrenergic Receptors | |
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Structural Determinants of [alpha subscript 2]-Adrenergic Receptor Regulation | |
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Regulation of D2 and D3 Receptors in Transfected Cells by Agonists and Antagonists | |
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Regulation of the D1 Dopamine Receptor through cAMP-Mediated Pathways | |
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Mechanisms for Activation of Multiple Effectors by [alpha subscript 1]-Adrenergic Receptors | |
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Signal Transduction Pathways Modulated by D2-Like Dopamine Receptors | |
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Guanosine Triphosphatase--Activating Proteins for Heterotrimetric G-Proteins | |
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Regulation of the Stoichiometry of Protein Components of the Stimulatory Adenylyl Cyclase Cascade | |
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Regulation of Mitogen-Activated Protein Kinase Pathways by Catecholamine Receptors | |
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Pharmacology | |
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Examination of Ligand-Induced Conformational Changes in the [beta subscript 2]-Adrenergic Receptor by Fluorescence Spectroscopy | |
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Relationship between [alpha subscript 2]-Adrenergic Receptors and Imidazoline/Guanidinium Receptive Sites | |
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Dopamine D4 Receptors May Alleviate Antipsychotic-Induced Parkonsonism | |
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Binding of Typical and Atypical Antipsychotic Drugs to Multiple Neurotransmitter Receptors | |
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Structural and Functional Characteristics of the Dopamine D4 Receptor | |
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NGD 94-1: A Specific Dopamine-4--Receptor Antagonist | |
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Catecholamine Receptors in Physiology and Behavior | |
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In Vivo Mutation of the [alpha subscript 2A]-Adrenergic Receptor by Homologous Recombination Reveals the Role of This Receptor Subtype in Multiple Physiological Processes | |
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Regulation of Fat-Cell Function by [alpha subscript 2]-Adrenergic Receptors | |
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The Developmental and Physiological Consequences of Disrupting Genes Encoding [beta subscript 1] and [beta subscript 2] Adrenoceptors | |
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Myocardial Overexpression of Adrenergic Receptors and Receptor Kinases | |
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Cardiac G-Protein Receptor Kinase Activity: Effect of a [beta]-Adrenergic Receptor Antagonist | |
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Structure and Function of the [beta subscript 3] Adrenoceptor | |
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Behavioral Analysis of Multiple DI-Like Dopamine Receptor Subtypes: New Agents and Studies in Transgenic Mice with DIA Receptor Knockout | |
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Antisense Knockdown of Brain Dopamine Receptors | |
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The Physiological Role of Dopamine D2 Receptors | |
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Pathophysiological States | |
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Regulation of DI Receptor Function in Spontaneous Hypertension | |
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Catecholamines in the Periphery | |
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Overview | |
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Assessment of Peripheral Catecholaminergic Function | |
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Peripheral Catecholaminergic Function Evaluated by Norepinephrine Measurements in Plasma, Extracellular Fluid, and Lymphocytes, from Nerve Recordings and Cellular Responses | |
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Cardiac Microdialysis | |
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Sympathetic Microneurography and Neurocirculatory Function: Studies of Ventricular Arrhythmias in Humans | |
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Catecholamines and Stress | |
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Stress as a Medical and Scientific Idea and Its Implications | |
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Stressor Specificity of Peripheral Catecholaminergic Activation | |
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Stressor-Specific Activation of Catecholaminergic Systems: Implications for Stress-Related Hypothalamic-Pituitary-Adrenocortical Responses | |
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Regulation of Gene Expression of Catecholamine Biosynthetic Enzymes by Stress | |
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Catecholamines and Pain | |
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Peripheral Modulatory Effects of Catecholamines in Inflammatory and Neuropathic Pain | |
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Brain Catecholamine Systems in Stress | |
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[alpha subscript 2]-Adrenergic Mechanisms of Analgesia: Strategies for Improving Their Therapeutic Window and Identification of the Novel, Potent [alpha subscript 2A]-Adrenergic Receptor Agonist, S 18616 | |
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Cellular Transplantation for Intractable Pain | |
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Catechnolamines and Neuroimmunology | |
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The Role of the Sympathetic Nervous System in the Modulation of Immune Responses | |
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Catecholamines, Catecholamine Receptors, Cell Adhesion Molecules, and Acute Stressor-Related Changes in Cellular Immunity | |
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Nerve Growth Factor and Autoimmune Disease: Role of Tumor Necrosis Factor-[alpha]? | |
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Adrenomedullary Secretion and Co-Secretion | |
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Multiple Transmitter Control of Catecholamine Secretion in Rat Adrenal Medulla | |
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Adrenomedullin in Cardiovascular Disease | |
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Strychnine, Glycine, and Adrenomedullary Secretion | |
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Neurocardiology | |
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Catecholamines and Neurocardiogenic Syncope | |
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[beta]-Blockers in Congestive Heart Failure: The Pharmacology of Carvedilol, a Vasodilating [beta]-Blocker and Antioxidant, and Its Therapeutic Utility in Congestive Heart Failure | |
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Sympathetic Cardioneurotherapy in Dysautonomias | |
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Catecholamines and Metabolism | |
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Hypoglycemia-Associated Autonomic Failure in Insulin-Dependent Diabetes Mellitus | |
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Mechanisms of the Sympathoadrenal Response to Hypoglycemia | |
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Importance of Catecholamines in Defense against Insulin Hypoglycemia in Humans | |
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Sympathetic Nervous Activity and the Thermic Effect of Food in Humans | |
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Microdialysis for the Assessment of Catecholamine-Induced Lipolysis in Human Adipose and Skeletal Muscle Tissue | |
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Catecholamines in the Brain and Regulation of the Cardiovascular System | |
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Bulbospinal Ci-Adrenergic Neurons: Electrophysiological Properties in the Neonate Rat | |
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Catecholamines, Opioids, and Vagal Afferents in the Nucleus of the Solitary Tract | |
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Agmatine: A Novel Neurotransmitter? | |
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Central and Peripheral Norepinephrine Kinetics in Heart Failure, Coronary Artery Disease, and Hypertension | |
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Catecholamines in the Central Nervous System | |
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Overview | |
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Dopamine-Mediated Gene Regulation in the Striatum | |
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Dopamine Control of Gene Expression in Basal Ganglia Nuclei: Striatal and Nonstriatal Mechanisms | |
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Dopaminergic Regulation of Immediate Early Gene Expression in the Basal Ganglia | |
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Dopamine and Calcium Signal Interactions in the Developing Straiatum: Control by Kinetics of CREB Phosphorylation | |
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The Phasic Reward Signal of Primate Dopamine Neurons | |
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Afferent Control of Midbrain Dopamine Neurons: An Intracellular Perspective | |
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GABAergic Control of the Firing Pattern of Substantia Nigra Dopaminergic Neurons | |
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Afferent Control of Substantia Nigra Compacta Dopamine Neurons: Anatomical Perspective and Role of Glutamatergic and Cholinergic Inputs | |
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Dopamine Axons in Primate Prefrontal Cortex: Specificity of Distribution, Synaptic Targets, and Development | |
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The Cortical Dopamine System: Role in Memory and Cognition | |
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Norepinephrine-Dopamine Interactions in the Prefrontal Cortex and the Ventral Tegmental Area: Relevance to Mental Diseases | |
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Dopamine Function in the Prefrontal Cortex | |
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The Modulation of Corticoaccumbens Transmission by Limbic Afferents and Dopamine: A Model for the Pathophysiology of Schizophrenia | |
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Dopamine Modulation of Responses Mediated by Excitatory Amino Acids in the Neostriatum | |
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The Molecular Basis of Dopamine and Glutamate Interactions in the Striatum | |
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Modulation by Dopamine of Rat Corticostriatal Input | |
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Dopamine, Glutamate, and Behavioral Correlates of Striatal Neuronal Activity | |
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State-Related Activity, Reactivity of Locus Ceruleus Neurons in Behaving Monkeys | |
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Modulation of Forebrain Electroencephalographic Activity and Behavioral State by the Locus Ceruleus-Noradrenergic System: Involvement of the Medial Septal Area | |
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New Perspectives on the Functional Organization and Postsynaptic Influences of the Locus Ceruleus Efferent Projection System | |
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Neuromodulation and Cognitive Performance: Recent Studies of Noradrenergic Locus Ceruleus in Behaving Monkeys | |
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Noradrenergic Effects on Activity of Prefrontal Cortical Neurons in Behaving Monkeys | |
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Noradrenergic Influences on Prefrontal Cortical Cognitive Function: Opposing Actions at Postjunctional [alpha subscript 1]-Versus [alpha subscript 2]-Adrenergic Receptors | |
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Afferent Control of Nucleus Locus Ceruleus: Differential Regulation by "Shell" and "Core" Inputs | |
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Sensory Response of the Locus Ceruleus: Neonatal and Adult Studies | |
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Noradrenergic Modulation of the Prefrontal Cortex as Revealed by Electron Microscopic Immunocytochemistry | |
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Activation of the Locus Ceruleus Brain Noradrenergic System during Stress: Circuitry, Consequences, and Regulation | |
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Norepinephrine and Schizophrenia: A New Hypothesis for Antipsychotic Drug Action | |
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Neurochemical Responses to Lesions of Dopaminergic Neurons: Implications for Compensation and Neuropathology | |
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Dopamine Receptor Subtypes as Targets for the Pharmacotherapy of Parkinson's Disease | |
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Free Radicals and MPTP-Induced Selective Destruction of Substantia Nigra Compacta Neurons | |
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Application of Gene Therapy for Parkinson's Disease: Nonhuman Primate Experience | |
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Prefrontal Cortical and Hippocampal Modulation of Dopamine-Mediated Effects | |
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Dysregulation of Mesoprefrontal Dopamine Neurons Induced by Acute and Repeated Phencyclidine Administration in the Nonhuman Primate: Implications for Schizophrenia | |
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Interactions between Catecholamines and Serotonin: Relevance to the Pharmacology of Schizophrenia | |
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Novel Catecholaminergic Systems | |
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Overview | |
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Catecholestrogens | |
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Catecholestrogens in the Induction of Tumors in the Kidney of the Syrian Hamster | |
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Biosynthesis and Inactivation of Catecholestrogens | |
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Catecholestrogens as Procarcinogens: Depurinating Adducts and Tumor Initiation | |
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Role of Aromatic Hydrocarbons in Disclosing How Catecholestrogens Initiate Cancer | |
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Embryo Implantation Requires Estrogen-Directed Uterine Preparation and Catecholestrogen-Mediated Embryonic Activation | |
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Nonneuronal Biosynthesis of Catecholamines | |
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Extra-Adrenal Nonneuronal Epinephrine and Phenylethanolamine-N-methyltransferase | |
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Dopamine and the Brain-Gut Axis | |
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Origin and Significance of Plasma Dihydroxyphenylalanine | |
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Is L-Dopa a Neurotransmitter? | |
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Is L-Dopa a Neurotransmitter of the Primary Baroreceptor Afferents Terminating in the Nucleus Tractus Solitarri of Rats? | |
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Immunocytochemical Evidence of Novel Catecholamineor Biopterin-Related Neurons of Mammalian Brain | |
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Fluorinated Dihydroxyphenylserines as Potential Biological Precursors of Fluorinated Norepinephrines | |
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Dopamine as a Renal Autocrine-Paracrine Substance | |
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Nonneuronal Dopamine | |
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The Renal Dopamine System | |
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Renal Dopamine Production and Release in the Rat: A Microdialysis Study | |
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Development and Plasticity | |
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Overview | |
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Inductive Interactions Underlie Neural Crest Formation | |
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Lineage Commitment and Fate of Neural Crest-Derived Neurogenic Cells | |
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The Differentiation of the Neurotransmitter Phenotypes in Chick Sympathetic Neurons | |
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Developmental Regulation of Neurotransmitters in Sympathetic Neurons | |
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Changes in Gene Expression in Adult Sympathetic Neurons after Axonal Injury | |
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Ontogeny of Vesicular Amine Transporter Expression in the Rat: New Perspectives on Aminergic Neuronal and Neuroendocrine Differentiation | |
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Specification and Survival of Dopaminergic Neurons in the Mammalian Midbrain | |
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Effects of Glial Cell Line-Derived Neurotrophic Factor on the Nigrostriatal Dopamine System in Rodents and Nonhuman Primates | |
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Cell Body Functions of Brain-Derived Neurotrophic Factor Increase Forebrain Dopamine Release and Serotonin Metabolism Determined with in Vivo Microdialysis | |
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Neurotrophin Modulation of Hippocampal Synaptic Transmission | |
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Genotype and Phenotype in Familial Dysautonomia | |
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A Gene Therapy Approach for the Treatment of Amyotrophic Lateral Sclerosis and Parkinson's Disease | |
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Characterization of Adrenal Chromaffin Progenitor Cells in Mice | |
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Evolution and Origin of the Diversity of Dopamine Receptors in Vertebrates | |
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Neurogenetics of Synaptic Transmission in Caenorhabditis elegans | |
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Decapitated Drosophila: A Novel System for the Study of Biogenic Amines | |
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Dopaminergic Control of Serotonergic Neuron Development in the Grasshopper Central Nervous System | |
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Noradrenergic Long-Term Potentiation in the Dentate Gyrus | |
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Rapid Acquisition of Discriminative Responding in Monkey Locus Coeruleus Neurons | |
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Catecholaminergic Contributions to Early Learning | |
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Interactions between Catecholamines and the Amygdala in Emotional Memory: Subclinical and Clinical Evidence | |
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Drug Abuse and Alcoholism | |
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Overview | |
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Circuits, Drugs, and Drug Addiction | |
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Homologies and Differences in the Actions of Drugs of Abuse and a Conventional Reinforcer (Food) on Dopamine Transmission: An Interpretative Framework of the Mechanism of Drug Dependence | |
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Drug-Induced Adaptations in Catecholamine Systems: On the Inevitability of Sensitization | |
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Neurobiological Substrates Underlying Conditioned Effects of Cocaine | |
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The Rate Hypothesis and Agonist Substitution Approaches to Cocaine Abuse Treatment | |
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Drugs of Abuse and Dopamine Cell Activity | |
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DI-Receptor Regulation of Synaptic Potentials in the Ventral Tegmental Area after Chronic Drug Abuse | |
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Neuroadaptations in Nucleus Accumbens Neurons Resulting from Repeated Cocaine Administration | |
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Dopamine Efflux Studies into the in Vivo Actions of Psychostimulant Drugs | |
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Psychostimulants and Neuropeptide Response | |
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Drugs of Abuse and Striatal Gene Expression | |
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Coordinated Expression of Dopamine Receptors in Neostriatal Medium Spiny Neurons | |
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Dopaminergic Genes and Substance Abuse | |
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Quantitative Trait Loci: Mapping Drug and Alcohol-Related Genes | |
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Nuclear Memory: Gene Transcription and Behavior | |
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Phosphorylation of Dopamine Transporters and Rapid Adaptation to Cocaine | |
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Index | |
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Contents of Previous Volumes | |