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Catecholamines Vol. 42 : Bridging Basic Science with Clinical Medicine

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ISBN-10: 0120329433

ISBN-13: 9780120329434

Edition: 1997

Authors: David S. Goldstein, Graeme Eisenhofer, Richard McCarty, M .W. Anders, Ferid Murad

List price: $167.95
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Description:

Focusing on all aspects of catecholamine research, from the very basic to medical, volume 42 of Advances in Pharmacology will be of interest to students and research workers in a variety of biomedical disciplines.
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Book details

List price: $167.95
Copyright year: 1997
Publisher: Elsevier Science & Technology Books
Binding: Hardcover
Pages: 1084
Size: 6.50" wide x 9.50" long x 2.25" tall
Weight: 3.850
Language: English

Contributors
Preface
Catecholamine Synthesis and Release
Overview
Regulation and Expression of Tyrosine Hydroxylase
The Effect of Phosphorylation at Ser-40 on the Structure and Thermal Stability of Tyrosine Hydroxylase
Factors Affecting Adrenal Medullary Catecholamine Biosynthesis and Release
Regulation of Tyrosine Hydroxylase by Neuropeptides
Regulation of Tyrosine Hydroxylase Gene Expression by Transsynaptic Mechanisms and Cell-Cell Contact
A New Regulatory Protein of Catecholamine Synthesizing-Enzyme Expression
Unique and Cell-Type-Specific Tyrosine Hydroxylase Gene Expression
Triple Colocalization of Tyrosine Hydroxylase, Calretinin, and Calbindin D-28k in the Periventricular-Hypophyseal Dopaminergic Neuronal System
Genetic Disorders Involving Recycling and Formation of Tetrahydrobiopterin
Genetic Basis of Dominant Dystonia
Mutations in the Tyrosine Hydroxylase Gene Cause Various Forms of L-Dopa-Responsive Dystonia
Catecholamine Biosynthetic Enzyme Expression in Neurological and Psychiatric Disorders
Other Catecholamine-Synthesizing Enzymes
Multiple Pathways in Regulation of Dopamine [beta]-Hydroxylase
Examining Adrenergic Roles in Development, Physiology, and Behavior through Targeted Disruption of the Mouse Dopamine [beta]-Hydroxylase Gene
Genetic Diseases of Hypotension
Dopamine [beta]-Hydroxylase Deficiency Associated with Mutations in a Copper Transporter Gene
Glucocorticoid-Phenylethanolamine-N-methyltransferase Interactions in Humans
Determinants of Phenylethanolamine-N-methyltransferase Expression
Neural Control of Phenylethanolamine-N-methyltransferase via Cholinergic Activation of Egr-I
Synexin (Annexin VII) Hypothesis for Ca[superscript 2+]/GTP-Regulated Exocytosis
Monoamine Transmitter Release from Small Synaptic and Large Dense-Core Vesicles
Calcium Channels for Exocytosis in Chromaffin Cells
Characteristics of Transmitter Secretion from Individual Sympathetic Varicosities
Neurotransmitter Release at Individual Sympathetic Varicosities, Boutons
Appropriate Target Cells Are Required for Maturation of Neurotransmitter Release Function of Sympathetic Neurons in Culture
Effects of Neuropeptide Y at Sympathetic Neuroeffector Junctions
Strategies for Receptor Control of Neurotransmitter Release
Pattern of Adenosine Triphosphate and Norepinephrine Release and Clearance: Consequences for Neurotransmission
Corelease of Norepinephrine and Adenosine Triphosphate from Sympathetic Neurones
Neuropeptide Y: An Adrenergic Cotransmitter, Vasoconstrictor, and a Nerve-Derived Vascular Growth Factor
Neuropeptide Y: A Cardiac Sympathetic Cotransmitter?
Biochemistry of Somatodendritic Dopamine Release in Substantia Nigra: An in Vivo Comparison with Striatal Dopamine Release
The Use of Dual-Probe Microdialysis for the Study of Catecholamine Release in the Brain and Pineal Gland
Kinetics and Geometry of the Excitatory Dopaminergic Transmission in the Rat Striatum in Vivo
In Vivo and in Vitro Assessment of Dopamine Uptake and Release
Catecholamine Reuptake and Storage
Overview
The Plasma Membrane Transporters
Molecular Physiology and Regulation of Catecholamine Transporters
Localization of Dopamine Transporter Protein by Microscopic Histochemistry
Cellular and Subcellular Localization of the Dopamine Transporter in Rat Cortex
Cloned Catecholamine Transporters Expressed in Polarized Epithelial Cells: Sorting, Drug Sensitivity, and lon-Coupling Stoichiometry
Inactivation of the Dopamine Transporter Reveals Essential Roles of Dopamine in the Control of Locomotion, Psychostimulant Response, and Pituitary Function
Role of Protein Kinase C and Second Messengers in Regulation of the Norepinephrine Transporter
Electrophysiological Analysis of Transporter Function
Voltammetric Approaches to Kinetics and Mechanism of the Norepinephrine Transporter
Voltage-Dependency of the Dopamine Transporter in Rat Brain
Modulation of Quantal Dopamine Release by Psychostimulants
Regulation of Dopamine Transporter mRNA Levels in the Central Nervous System
Structural Diversity in the Catecholamine Transporter Gene Family: Molecular Cloning and Characterization of an L-Epinephrine Transporter from Bullfrog Sympathetic Ganglia
Positron Emission Tomography Radiogands for Dopamine Transporters and Studies in Human and Nonhuman Primates
Single Photon Emission Computed Tomography Imaging of Dopaminergic Function: Presynaptic Transporter, Postsynaptic Receptor, and "Intrasynaptic" Transmitter
Dopamine Transporter Changes in Neuropsychiatric Disorders
Vesicular Transporters and Catecholamine Storage
Molecular and Biochemical Studies of Rat Vesicular Monoamine Transporter
A Chimeric Vesicular Monoamine Transporter Dissociates Senitivity to Tetrabenazine and Unsubstituted Aromatic Amines
Ligand Recognition by the Vesicular Monoamine Transporters
Molecular Pharmacology of the Vesicular Monoamine Transporter
Ultrastructural Localization of the Vesicular Monoamine Transporter 2 in Mesolimbic and Nigrostriatal Dopaminergic Neurons
ICA 512, Receptor Tyrosine Phosphatase-Like Protein, Is Concentrated in Neurosecretory Granule Membranes
Protein Targeting in Neurons and Endocrine Cells
The Vesicular Monoamine Transporter VMAT2 and Vesicular Acetylcholine Transporter VAChT Are Sorted to Separate Vesicle Populations in PC12 Cells
Recycling of Synaptic Vesicles
The Secretory Cocktail of Adrenergic Large Dense-Core Vesicles: The Functional Role of the Chromogranins
A Novel, Catecholamine Release-Inhibitory Peptide from Chromogranin A: Autocrine Control of Nicotinic Cholinergic-Stimulated Exocytosis
Transcription Regulation Coupled to Calcium and Protein Kinase Signaling Systems through TRE- and CRE-Like Sequences in Neuropeptide Genes
Imaging of Monoaminergic and Cholinergic Vesicular Transporters in the Brain
Catecholamine Metabolism: From Molecular Understanding to Clinical Diagnosis and Treatment
Overview
Monoamine Oxidase
Monoamine Oxidase A and B: Structure, Function, and Behavior
Genetic Deficiencies of Monoamine Oxidase Isoenzymes: A Key to Understanding the Function of the Enzymes in Humans
Biological Markers, with Special Regard to Platelet Monoamine Oxidase (trbc-MAO), for Personality and Personality Disorders
Visualization of Monoamine Oxidase in Human Brain
Aliphatic N-Methylpropargylamines: Monoamine Oxidase-B Inhibitors and Antiapoptotic Drugs
Antiapoptotic Actions of Monoamine Oxidase B Inhibitors
Therapeutic Actions of L-Deprenyl in Dogs: A Model of Human Brain Aging
Apomorphine Is a Potent Radical Scavenger and Protects Cultured Pheochromocytoma Cells from H[subscript 2]O[subscript 2]-Induced Cell Death
O-Methylation and Conjugation
Catechol O-Methyltransferase: Characterization of the Protein, Its Gene, and the Preclinical Pharmacology of COMT Inhibitors
X-Ray Crystallography of Catechol O-Methyltransferase: Perspectives for Target-Based Drug Development
Catechol O-Methyltransferase Inhibition and the Treatment of Parkinson's Disease
The Structure and Function of the UDP-Glucuronosyltransferase Gene Family
Catecholamine Sulfation in Health and Disease
Metabolism of Endobiotics and Xenobiotics by UDP-Glucuronosyltransferase
Catecholamine Metabolizing Systems
Molecular Structure of the Carrier Responsible for Hepatic Uptake of Catecholamines
Catecholamine Uptake and Metabolism in the Liver
Catecholamine Uptake and Metabolism in Rat Lungs
The Extraneuronal Monoamine Transporter Exists in Human Central Nervous System Glia
Removal of Circulating Catecholamines by Extraneuronal Amine Transport Systems
Catecholamine Metabolites in Internal Jugular Plasma: A Window into the Human Brain
Norepinephrine Metabolites in Plasma as Indicators of Pharmacological Inhibition of Monoamine Oxidase and Catechol O-Methyltransferase
The Adrenal Gland as a Source of Dihydroxyphenylalanine and Catecholamine Metabolites
Clues to the Diagnosis of Pheochromocytoma from the Differential Tissue Metabolism of Catecholamines
Catecholamine Receptors and Signal Transduction
Overview
Structure, Classification, and Tissue Localization of Catecholamine Receptor Subtypes
Expression and Regulation of [alpha subscript 1]-Adrenergic Receptors in Human Tissues
[alpha subscript 1]-Adrenoceptor Subtypes in the Human Cardiovascular and Urogenital Systems
Molecular Mechanisms of Ligand Binding and Activation of [alpha subscript 1]-Adrenergic Receptors
Expansion of the Dopamine D1 Receptor Gene Family: Defining Molecular, Pharmacological, and Functional Criteria for D1A, D1B, D1C, and D1D Receptors
D1/D3 Receptor Relationships in Brain: Coexpression, Coactivation, and Coregulation
Mapping the Binding-Site Crevice of the D2 Receptor
Intracellular Mechanisms
Mechanisms of [beta]-Adrenergic Receptor Desensitization and Resensitization
Role of [beta]-Arrestins in the Intracellular Trafficking of G-Protein-Coupled Receptors
G-Protein-Linked Receptors as Substrates for Tyrosine Kinases: Cross-Talk in Signaling
Role of Arrestins in G-Protein-Coupled Receptor Endocytosis
Subtype-Specific Regulation of the [beta]-Adrenergic Receptors
Structural Determinants of [alpha subscript 2]-Adrenergic Receptor Regulation
Regulation of D2 and D3 Receptors in Transfected Cells by Agonists and Antagonists
Regulation of the D1 Dopamine Receptor through cAMP-Mediated Pathways
Mechanisms for Activation of Multiple Effectors by [alpha subscript 1]-Adrenergic Receptors
Signal Transduction Pathways Modulated by D2-Like Dopamine Receptors
Guanosine Triphosphatase--Activating Proteins for Heterotrimetric G-Proteins
Regulation of the Stoichiometry of Protein Components of the Stimulatory Adenylyl Cyclase Cascade
Regulation of Mitogen-Activated Protein Kinase Pathways by Catecholamine Receptors
Pharmacology
Examination of Ligand-Induced Conformational Changes in the [beta subscript 2]-Adrenergic Receptor by Fluorescence Spectroscopy
Relationship between [alpha subscript 2]-Adrenergic Receptors and Imidazoline/Guanidinium Receptive Sites
Dopamine D4 Receptors May Alleviate Antipsychotic-Induced Parkonsonism
Binding of Typical and Atypical Antipsychotic Drugs to Multiple Neurotransmitter Receptors
Structural and Functional Characteristics of the Dopamine D4 Receptor
NGD 94-1: A Specific Dopamine-4--Receptor Antagonist
Catecholamine Receptors in Physiology and Behavior
In Vivo Mutation of the [alpha subscript 2A]-Adrenergic Receptor by Homologous Recombination Reveals the Role of This Receptor Subtype in Multiple Physiological Processes
Regulation of Fat-Cell Function by [alpha subscript 2]-Adrenergic Receptors
The Developmental and Physiological Consequences of Disrupting Genes Encoding [beta subscript 1] and [beta subscript 2] Adrenoceptors
Myocardial Overexpression of Adrenergic Receptors and Receptor Kinases
Cardiac G-Protein Receptor Kinase Activity: Effect of a [beta]-Adrenergic Receptor Antagonist
Structure and Function of the [beta subscript 3] Adrenoceptor
Behavioral Analysis of Multiple DI-Like Dopamine Receptor Subtypes: New Agents and Studies in Transgenic Mice with DIA Receptor Knockout
Antisense Knockdown of Brain Dopamine Receptors
The Physiological Role of Dopamine D2 Receptors
Pathophysiological States
Regulation of DI Receptor Function in Spontaneous Hypertension
Catecholamines in the Periphery
Overview
Assessment of Peripheral Catecholaminergic Function
Peripheral Catecholaminergic Function Evaluated by Norepinephrine Measurements in Plasma, Extracellular Fluid, and Lymphocytes, from Nerve Recordings and Cellular Responses
Cardiac Microdialysis
Sympathetic Microneurography and Neurocirculatory Function: Studies of Ventricular Arrhythmias in Humans
Catecholamines and Stress
Stress as a Medical and Scientific Idea and Its Implications
Stressor Specificity of Peripheral Catecholaminergic Activation
Stressor-Specific Activation of Catecholaminergic Systems: Implications for Stress-Related Hypothalamic-Pituitary-Adrenocortical Responses
Regulation of Gene Expression of Catecholamine Biosynthetic Enzymes by Stress
Catecholamines and Pain
Peripheral Modulatory Effects of Catecholamines in Inflammatory and Neuropathic Pain
Brain Catecholamine Systems in Stress
[alpha subscript 2]-Adrenergic Mechanisms of Analgesia: Strategies for Improving Their Therapeutic Window and Identification of the Novel, Potent [alpha subscript 2A]-Adrenergic Receptor Agonist, S 18616
Cellular Transplantation for Intractable Pain
Catechnolamines and Neuroimmunology
The Role of the Sympathetic Nervous System in the Modulation of Immune Responses
Catecholamines, Catecholamine Receptors, Cell Adhesion Molecules, and Acute Stressor-Related Changes in Cellular Immunity
Nerve Growth Factor and Autoimmune Disease: Role of Tumor Necrosis Factor-[alpha]?
Adrenomedullary Secretion and Co-Secretion
Multiple Transmitter Control of Catecholamine Secretion in Rat Adrenal Medulla
Adrenomedullin in Cardiovascular Disease
Strychnine, Glycine, and Adrenomedullary Secretion
Neurocardiology
Catecholamines and Neurocardiogenic Syncope
[beta]-Blockers in Congestive Heart Failure: The Pharmacology of Carvedilol, a Vasodilating [beta]-Blocker and Antioxidant, and Its Therapeutic Utility in Congestive Heart Failure
Sympathetic Cardioneurotherapy in Dysautonomias
Catecholamines and Metabolism
Hypoglycemia-Associated Autonomic Failure in Insulin-Dependent Diabetes Mellitus
Mechanisms of the Sympathoadrenal Response to Hypoglycemia
Importance of Catecholamines in Defense against Insulin Hypoglycemia in Humans
Sympathetic Nervous Activity and the Thermic Effect of Food in Humans
Microdialysis for the Assessment of Catecholamine-Induced Lipolysis in Human Adipose and Skeletal Muscle Tissue
Catecholamines in the Brain and Regulation of the Cardiovascular System
Bulbospinal Ci-Adrenergic Neurons: Electrophysiological Properties in the Neonate Rat
Catecholamines, Opioids, and Vagal Afferents in the Nucleus of the Solitary Tract
Agmatine: A Novel Neurotransmitter?
Central and Peripheral Norepinephrine Kinetics in Heart Failure, Coronary Artery Disease, and Hypertension
Catecholamines in the Central Nervous System
Overview
Dopamine-Mediated Gene Regulation in the Striatum
Dopamine Control of Gene Expression in Basal Ganglia Nuclei: Striatal and Nonstriatal Mechanisms
Dopaminergic Regulation of Immediate Early Gene Expression in the Basal Ganglia
Dopamine and Calcium Signal Interactions in the Developing Straiatum: Control by Kinetics of CREB Phosphorylation
The Phasic Reward Signal of Primate Dopamine Neurons
Afferent Control of Midbrain Dopamine Neurons: An Intracellular Perspective
GABAergic Control of the Firing Pattern of Substantia Nigra Dopaminergic Neurons
Afferent Control of Substantia Nigra Compacta Dopamine Neurons: Anatomical Perspective and Role of Glutamatergic and Cholinergic Inputs
Dopamine Axons in Primate Prefrontal Cortex: Specificity of Distribution, Synaptic Targets, and Development
The Cortical Dopamine System: Role in Memory and Cognition
Norepinephrine-Dopamine Interactions in the Prefrontal Cortex and the Ventral Tegmental Area: Relevance to Mental Diseases
Dopamine Function in the Prefrontal Cortex
The Modulation of Corticoaccumbens Transmission by Limbic Afferents and Dopamine: A Model for the Pathophysiology of Schizophrenia
Dopamine Modulation of Responses Mediated by Excitatory Amino Acids in the Neostriatum
The Molecular Basis of Dopamine and Glutamate Interactions in the Striatum
Modulation by Dopamine of Rat Corticostriatal Input
Dopamine, Glutamate, and Behavioral Correlates of Striatal Neuronal Activity
State-Related Activity, Reactivity of Locus Ceruleus Neurons in Behaving Monkeys
Modulation of Forebrain Electroencephalographic Activity and Behavioral State by the Locus Ceruleus-Noradrenergic System: Involvement of the Medial Septal Area
New Perspectives on the Functional Organization and Postsynaptic Influences of the Locus Ceruleus Efferent Projection System
Neuromodulation and Cognitive Performance: Recent Studies of Noradrenergic Locus Ceruleus in Behaving Monkeys
Noradrenergic Effects on Activity of Prefrontal Cortical Neurons in Behaving Monkeys
Noradrenergic Influences on Prefrontal Cortical Cognitive Function: Opposing Actions at Postjunctional [alpha subscript 1]-Versus [alpha subscript 2]-Adrenergic Receptors
Afferent Control of Nucleus Locus Ceruleus: Differential Regulation by "Shell" and "Core" Inputs
Sensory Response of the Locus Ceruleus: Neonatal and Adult Studies
Noradrenergic Modulation of the Prefrontal Cortex as Revealed by Electron Microscopic Immunocytochemistry
Activation of the Locus Ceruleus Brain Noradrenergic System during Stress: Circuitry, Consequences, and Regulation
Norepinephrine and Schizophrenia: A New Hypothesis for Antipsychotic Drug Action
Neurochemical Responses to Lesions of Dopaminergic Neurons: Implications for Compensation and Neuropathology
Dopamine Receptor Subtypes as Targets for the Pharmacotherapy of Parkinson's Disease
Free Radicals and MPTP-Induced Selective Destruction of Substantia Nigra Compacta Neurons
Application of Gene Therapy for Parkinson's Disease: Nonhuman Primate Experience
Prefrontal Cortical and Hippocampal Modulation of Dopamine-Mediated Effects
Dysregulation of Mesoprefrontal Dopamine Neurons Induced by Acute and Repeated Phencyclidine Administration in the Nonhuman Primate: Implications for Schizophrenia
Interactions between Catecholamines and Serotonin: Relevance to the Pharmacology of Schizophrenia
Novel Catecholaminergic Systems
Overview
Catecholestrogens
Catecholestrogens in the Induction of Tumors in the Kidney of the Syrian Hamster
Biosynthesis and Inactivation of Catecholestrogens
Catecholestrogens as Procarcinogens: Depurinating Adducts and Tumor Initiation
Role of Aromatic Hydrocarbons in Disclosing How Catecholestrogens Initiate Cancer
Embryo Implantation Requires Estrogen-Directed Uterine Preparation and Catecholestrogen-Mediated Embryonic Activation
Nonneuronal Biosynthesis of Catecholamines
Extra-Adrenal Nonneuronal Epinephrine and Phenylethanolamine-N-methyltransferase
Dopamine and the Brain-Gut Axis
Origin and Significance of Plasma Dihydroxyphenylalanine
Is L-Dopa a Neurotransmitter?
Is L-Dopa a Neurotransmitter of the Primary Baroreceptor Afferents Terminating in the Nucleus Tractus Solitarri of Rats?
Immunocytochemical Evidence of Novel Catecholamineor Biopterin-Related Neurons of Mammalian Brain
Fluorinated Dihydroxyphenylserines as Potential Biological Precursors of Fluorinated Norepinephrines
Dopamine as a Renal Autocrine-Paracrine Substance
Nonneuronal Dopamine
The Renal Dopamine System
Renal Dopamine Production and Release in the Rat: A Microdialysis Study
Development and Plasticity
Overview
Inductive Interactions Underlie Neural Crest Formation
Lineage Commitment and Fate of Neural Crest-Derived Neurogenic Cells
The Differentiation of the Neurotransmitter Phenotypes in Chick Sympathetic Neurons
Developmental Regulation of Neurotransmitters in Sympathetic Neurons
Changes in Gene Expression in Adult Sympathetic Neurons after Axonal Injury
Ontogeny of Vesicular Amine Transporter Expression in the Rat: New Perspectives on Aminergic Neuronal and Neuroendocrine Differentiation
Specification and Survival of Dopaminergic Neurons in the Mammalian Midbrain
Effects of Glial Cell Line-Derived Neurotrophic Factor on the Nigrostriatal Dopamine System in Rodents and Nonhuman Primates
Cell Body Functions of Brain-Derived Neurotrophic Factor Increase Forebrain Dopamine Release and Serotonin Metabolism Determined with in Vivo Microdialysis
Neurotrophin Modulation of Hippocampal Synaptic Transmission
Genotype and Phenotype in Familial Dysautonomia
A Gene Therapy Approach for the Treatment of Amyotrophic Lateral Sclerosis and Parkinson's Disease
Characterization of Adrenal Chromaffin Progenitor Cells in Mice
Evolution and Origin of the Diversity of Dopamine Receptors in Vertebrates
Neurogenetics of Synaptic Transmission in Caenorhabditis elegans
Decapitated Drosophila: A Novel System for the Study of Biogenic Amines
Dopaminergic Control of Serotonergic Neuron Development in the Grasshopper Central Nervous System
Noradrenergic Long-Term Potentiation in the Dentate Gyrus
Rapid Acquisition of Discriminative Responding in Monkey Locus Coeruleus Neurons
Catecholaminergic Contributions to Early Learning
Interactions between Catecholamines and the Amygdala in Emotional Memory: Subclinical and Clinical Evidence
Drug Abuse and Alcoholism
Overview
Circuits, Drugs, and Drug Addiction
Homologies and Differences in the Actions of Drugs of Abuse and a Conventional Reinforcer (Food) on Dopamine Transmission: An Interpretative Framework of the Mechanism of Drug Dependence
Drug-Induced Adaptations in Catecholamine Systems: On the Inevitability of Sensitization
Neurobiological Substrates Underlying Conditioned Effects of Cocaine
The Rate Hypothesis and Agonist Substitution Approaches to Cocaine Abuse Treatment
Drugs of Abuse and Dopamine Cell Activity
DI-Receptor Regulation of Synaptic Potentials in the Ventral Tegmental Area after Chronic Drug Abuse
Neuroadaptations in Nucleus Accumbens Neurons Resulting from Repeated Cocaine Administration
Dopamine Efflux Studies into the in Vivo Actions of Psychostimulant Drugs
Psychostimulants and Neuropeptide Response
Drugs of Abuse and Striatal Gene Expression
Coordinated Expression of Dopamine Receptors in Neostriatal Medium Spiny Neurons
Dopaminergic Genes and Substance Abuse
Quantitative Trait Loci: Mapping Drug and Alcohol-Related Genes
Nuclear Memory: Gene Transcription and Behavior
Phosphorylation of Dopamine Transporters and Rapid Adaptation to Cocaine
Index
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