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| Preface | |
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| Acknowledgements | |
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| Introduction | |
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| The development of high-resolution NMR | |
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| Modern NMR and this book | |
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| Applying modern NMR techniques | |
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| References | |
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| Introducing High-resolution NMR | |
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| Nuclear spin and resonance | |
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| The vector model and pulse excitation | |
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| Time and frequency domains | |
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| Spin relaxation | |
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| Mechanisms for relaxation | |
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| References | |
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| Practical Aspects of High-resolution NMR | |
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| An overview of the NMR spectrometer | |
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| Data acquisition and processing | |
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| Preparing the sample | |
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| Preparing the spectrometer | |
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| Spectrometer calibrations | |
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| Spectrometer performance tests | |
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| References | |
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| One-dimensional Techniques | |
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| The single-pulse experiment | |
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| Spin decoupling methods | |
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| Spectrum editing with spin-echoes | |
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| Sensitivity enhancement and spectrum editing | |
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| Observing quadrupolar nuclei | |
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| References | |
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| Correlations through the Chemical Bond I: Homonuclear Shift Correlation | |
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| Introducing the second dimension | |
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| Correlation spectroscopy (COSY) | |
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| Practical aspects of 2D NMR | |
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| Coherence and coherence transfer | |
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| Gradient-selected spectroscopy | |
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| Alternative COSY sequences | |
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| Total correlation spectroscopy (TOCSY) | |
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| Correlating dilute spins: INADEQUATE | |
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| References | |
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| Correlations through the Chemical Bond II: Heteronuclear Shift Correlation | |
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| Introduction | |
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| Sensitivity | |
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| Heteronuclear single-bond correlation spectroscopy | |
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| Heteronuclear multiple-bond correlation spectroscopy | |
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| Traditional X-detected correlation spectroscopy | |
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| References | |
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| Separating Shifts and Couplings: J-resolved Spectroscopy | |
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| Introduction | |
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| Heteronuclear J-resolved spectroscopy | |
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| Homonuclear J-resolved spectroscopy | |
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| ""Indirect"" homonuclear J-resolved spectroscopy | |
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| References | |
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| Correlations through Space: The Nuclear Overhauser Effect | |
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| Theoretical Aspects | |
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| Introduction | |
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| Definition of the NOE | |
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| Steady-state NOEs | |
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| Transient NOEs | |
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| Rotating-frame NOEs | |
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| Practical Aspects | |
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| Measuring steady-state NOEs: NOE difference | |
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| Measuring transient NOEs: NOESY | |
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| Measuring rotating-frame NOEs: ROESY | |
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| Measuring heteronuclear NOEs | |
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| Experimental considerations | |
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| References | |
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| Experimental Methods | |
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| Composite pulses | |
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| Broadband decoupling and spin-locks | |
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| Selective excitation and shaped pulses | |
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| Solvent suppression | |
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| Recent methods | |
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| References | |
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| Glossary of Acronyms | |
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| Index | |