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Preface | |
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Renal Functions, Basic Processes, and Anatomy | |
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Renal Functions | |
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Overview of Renal Processes | |
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Anatomy of the Kidneys and Urinary System | |
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The Tubular System | |
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Basic Renal Excretory Processes | |
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Renal Blood Flow and Glomerular Filtration | |
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Renal Blood Flow | |
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Flow, Resistance, and Blood Pressure in the Kidneys | |
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Glomerular Filtration | |
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Autoregulation | |
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Clearance | |
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The Clearance Concept | |
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Clearance Units | |
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Basic Transport Mechanisms | |
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Transepithelial Transport | |
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Receptor-Mediated Endocytosis and Transcytosis | |
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Proximal Tubule Reabsorption | |
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Renal Handling of Organic Solutes | |
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Overview | |
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Proximal Reabsorption of Organic Nutrients | |
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Proteins and Peptides | |
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Proximal Secretion of Organic Cations | |
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Proximal Secretion of Organic Anions | |
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pH Dependence of Passive Reabsorption or Secretion | |
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Urea | |
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Basic Renal Processes for Sodium, Chloride, and Water | |
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Overview | |
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Individual Tubular Segments | |
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Urinary Concentration: The Medullary Osmotic Gradient | |
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Frequently Asked Questions | |
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Regulation of Sodium and Water Excretion | |
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The Goals of Regulation | |
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Sodium Excretion: The Cardiovascular Connection | |
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Major Controllers of Sodium Excretion: Sympathetic Stimulation | |
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Major Controllers of Sodium Excretion: The Renin-Angiotensin System | |
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Control of Water Excretion | |
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Regulation of Potassium Balance | |
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Regulation of Potassium Movement between the Intracellular and Extracellular Compartments | |
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Renal Potassium Handling | |
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Control of Potassium Excretion | |
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Regulation of Acid-Base Balance | |
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Overview | |
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Acid-Base Fundamentals | |
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Sources of Acids and Bases | |
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Renal Transport of Acids and Bases | |
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Regulation of the Renal Handling of Acids and Bases | |
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Control of Renal Glutamine Metabolism and Ammonium Excretion | |
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Acid-Base Disorders and Their Compensation | |
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Regulation of Calcium, Magnesium, and Phosphate | |
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Overview | |
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Effector Sites for Calcium Balance | |
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The Physiology of Phosphate | |
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Hormonal Control of Calcium and Phosphate | |
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Summary of Normal Calcium and Phosphate Regulation | |
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Magnesium Physiology and Renal Handling | |
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Answers to Study Questions | |
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Index | |