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Williams Hematology

ISBN-10: 0071621512
ISBN-13: 9780071621519
Edition: 8th 2010
List price: $294.95 Buy it from $64.59
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Book details

List price: $294.95
Edition: 8th
Copyright year: 2010
Publisher: McGraw-Hill Professional Publishing
Publication date: 7/9/2010
Binding: Mixed Media
Pages: 2460
Size: 9.00" wide x 11.00" long x 3.00" tall
Weight: 1.540
Language: English

Author Profile The Williams' editorial team truly represents the cream of the crop of research and clinical hematology. The editors are all known worldwide for their contributions to the field. Three editors are previous or current Presidents of the American Society of Hematology.The editor-in-chief of the 8th edition,Kenneth Kaushansky MD,is Chairman of Medicine at the University of California San Diego School of Medicine. He is current Present of the American Society of Hematology.

Contributors
Preface
Clinical Evaluation of the Patient
Initial Approach to the Patient: History and Physical Examination
Examination of Blood Cells
Examination of the Marrow, Daniel H. Ryan
the Organization of the Lymphohematopoietic Tissues
Structure of the Marrow and the Hematopoietic Microenvironment
The Organization and Structure of Lymphoid Tissues
Epochal Hematology
Hematology of the Fetus and Newborn
Hematology during Pregnancy
Hematology in Older Persons
Molecular and Cellular Hematology
Genetic Principles and Molecular Biology
Genomics and Epigenetics
Cytogenetics and Molecular Abnormalities
Apoptosis
Cell-Cycle Regulation and Hematologic Disorders
Signal Transduction Pathways
The Cluster of Differentiation Antigens
Hematopoietic Stem Cells
The Inflammatory Process
Innate Immunity
Dendritic Cells and the Control of Innate Adaptive Immunity
Therapeutic Principles
Pharmacology and Toxicity of Antineoplastic Drugs
Principles of Hematopoietic Cell Transplantation
Treatment of Infections in the Immunocompromised Host
Principles of Antithrombotic Therapy
Principles of Immune Cell Therapy
Principles of Vaccine Therapy
Principles of Therapeutic Apheresis: Indications, Efficacy, and Complications
Principles of Gene Transfer for Therapy
Regenerative Medicine: Principles of Multipotential Cell Therapy for Tissue Replacement
The Erythrocyte
Morphology of the Erythron
Composition of the Erythrocyte, Ernest Beutler
Production of Erythrocytes
Destruction of Erythrocytes, Ernest Beutler
Clinical Manifestations and Classification of Erythrocyte Disorders
Aplastic Anemia: Acquired and Inherited
Pure Red Cell Aplasia
Anemia of Chronic Renal Disease
Anemia of Chronic Disease
Anemia of Endocrine Disorders
The Congenital Dyserythropoietic Anemias
Paroxysmal Nocturnal Hemoglobinuria
Folate, Cobalamin, and Megaloblastic Anemias
Disorders of Iron Metabolism, Ernest Beutler
Anemia Resulting from Other Nutritional Deficiencies
Anemia Associated with Marrow Infiltration
The Red Blood Cell Membrane and Its Disorders: Hereditary Spherocytosis, Elliptocytosis, and Related Diseaes
Disorders of Red Cells Resulting from Enzyme Abnormalities
The Thalassemias: Disorders of Globin Synthesis
Disorders of Hemoglobin Structure: Sickle Cell Anemia and Related Abnormalities
Methemoglobinemia and Other Dyshemoglobinemias
Hemolytic Anemia Resulting from Physical Injury to Red Cells
Hemolytic Anemia Resulting from Chemical and Physical Agents
Hemolytic Anemia Resulting from Infections with Microorganisms
Hemolytic Anemia Resulting from Immune Injury
Alloimmune Hemolytic Disease of the Fetus and Newborn
Hypersplenism and Hyposlenism
Primary and Secondary Polycythemias (Erythrocytosis)
The Porphyrias
Hereditary and Acquired Sideroblastic Anemias
Neutrophils, Eosinophils, Basophils, and Mast Cells
Morphology of Neutrophils, Eosinophils, and Basophils
Composition of Neutrophils
Production, Distribution, and Fate of Neutrophils
Eosinophils and Their Disorders
Basophils and Mast Cells and Their Disorders
Classification and Clinical Manifestations of Neutrophil Disorders
Neutropenia and Neutrophilia
Disorders of Neutrophil Function
Monocytes and Macrophages
Morphology of Monocytes and Macrophages
Biochemistry and Functions of Monocytes and Macrophages
Production, Distribution, and Fate of Monocytes and Macrophages
Classification and Clinical Manifestations of Disorders of Monocytes and Macrophages
Monocytosis and Monocytopenia
Inflammatory and Malignant Histiocytosis
Lipid Storage Diseases
Lymphocytes and Plasma Cells
Morphology of Lymphocytes and Plasma Cells
Composition and Biochemistry of Lymphocytes and Plasma Cells
Lymphopoiesis
Functions of B Lymphocytes and Plasma Cells in Immunoglobulin Production
Functions of T Lymphocytes: T-Cell Receptors for Antigen
Functions of Natural Killer Cells
Classification and Clinical Manifestations of Lymphocyte and Plasma Cell Disorders
Lymphocytosis and Lymphocytopenia
Immunodeficiency Diseases
Hematologic Manifestations of Acquired Immunodeficiency Syndrome
Mononucleosis Syndromes
Neoplastic Myeloid Diseases
Classification and Clinical Manifestations of the Clonal Myeloid Disorders
Polycythemia Vera
Essential Thrombocythemia
Myelodysplastic Syndromes (Clonal Cytopenias and Oligoblastic Myelogenous Leukemia)
Acute Myelogenous Leukemia
Chronic Myelogenous Leukemia and Related Disorders
Primary Myelofibrosis
Neoplastic Lymphoid Diseases
Classification of Malignant Lymphoid Disorders
Acute Lymphoblastic Leukemia
Chronic Lymphocytic Leukemia and Related Diseases
Hairy Cell Leukemia
Large Granular Lymphocytic Leukemia
General Considerations of Lymphoma: Epidemiology, Etiology, Heterogeneity, and Primary Extranodel Disease
Pathology of Malignant Lymphomas
Hodgkin Lymphoma
Diffuse Large B-Cell Lymphoma
Follicular Lymphoma
Mantle Cell Lymphoma
Marginal Zone B-Cell Lymphomas
Burkitt Lymphoma
Cutaneous T-Cell Lymphoma (Mycosis Fungoides and Sezary Syndrome)
Mature T-Cell and Natural Killer Cell Lymphomas
Plasma Cell Neoplasms: General Considerations, H. Elizabeth Broome
Essential Monoclonal Gammopathy
Myeloma
The Amyloidoses
Macroglobulinemia
Heavy-Chain Disease
Hemostatis and Thrombosis
Megakaryopoiesis and Thrombopoiesis
Platelet Morphology, Biochemistry, and Function
Molecular Biology and Biochemistry of the Coagulation Factors and Pathways of Hemostatis
Control of Coagulation Reactions
Vascular Function in Hemostatis
Classification, Clinical Manifestations, and Evaluation of Disorders of Hemostatis
Thrombocytopenia
Reactive Thrombocytosis
Hereditary Qualitative Platelet Disorders
Acquired Qualitative Platelet Disorders
The Vascular Purpuras
Hemophilia a and Hemophilia B
Inherited Deficiencies of Coagulation Factors II, V, VII, X, XI, and XIII and Combined Deficiencies of Factors V and VIII and of the Vitamin K-Dependent Factors
Hereditary Fibrinogen Abnormalities
Von Willebrand Disease
Antibody-Mediated Coagulation Factor Deficiencies, Pete Lollar
Hemostatic Dysfunction Related to Liver Diseases and Liver Transplantation
Disseminated Intravascular Coagulation
Hereditary Thrombophilia
The Antiphospholipid Syndrome
Antibody-Mediated Thrombotic Disorders: Thrombotic-Thrombocytopenic Purpura and Heparin-Induced Thrombocytopenia
Venous Thrombosis
Atherothrombosis: Disease Initiation, Progression, and Treatment
Fibrinolysis and Thrombolysis
Transfusion Medicine
Erythrocyte Antigens and Antibodies
Human Leukocyte and Platelet Antigens
Blood Procurement and Screening
Red Cell Transfusion
Preservation and Clinical Use of Platelets
Index

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