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Blood-Brain Barrier Drug Delivery and Brain Pathology

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ISBN-10: 1461351413

ISBN-13: 9781461351412

Edition: 2001

Authors: David Kobiler, Shlomo Lustig, Shlomo Shapira

List price: $54.99
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Description:

These proceedings review and discuss the different aspects of the biology of the Blood-Brain Barrier (BBB) and its involvement in the pathogenesis of brain disorders. The BBB, formed by a complex cellular system of endothelial cells, astroglia, pericytes, perivascular macrophages and a basal membrane, serves as a controlled functional gate to CNS. In vitro and in vivo models have been established to study the cellular and molecular interaction within the BBB and between the BBB and the neural cells. The structural and functional integrity of the BBB was shown to be dramatically altered during various diseases of the CNS, including neoplasia, ischemia, trauma, inflammation and bacterial and…    
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Book details

List price: $54.99
Copyright year: 2001
Publisher: Springer
Publication date: 11/5/2012
Binding: Paperback
Pages: 434
Size: 7.01" wide x 10.00" long x 0.36" tall
Weight: 1.870
Language: English