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    Mineralized Tissues in Oral and Craniofacial Science Biological Principles and Clinical Correlates

    ISBN-10: 0470958332
    ISBN-13: 9780470958339
    Author(s): Laurie K. McCauley, Martha J. Somerman
    Description: Mineralized Tissues in Oral and Craniofacial Science is a major comprehensive update on knowledge in the field of mineralized tissues in the oral and craniofacial region. Drs. McCauley and Somerman assembled an international team of researchers and  More...
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    List Price: $169.99
    Publisher: John Wiley & Sons, Incorporated
    Binding: Hardcover
    Pages: 392
    Size: 8.00" wide x 11.00" long x 1.00" tall
    Weight: 2.882
    Language: English

    Mineralized Tissues in Oral and Craniofacial Science is a major comprehensive update on knowledge in the field of mineralized tissues in the oral and craniofacial region. Drs. McCauley and Somerman assembled an international team of researchers and clinicians, offering a global perspective on the current knowledge in this field. Basic and clinical correlates reinforce the significance of research to clinical diagnoses and therapies, written in a manner that lends easily to their use for case study teaching venues.Section 1 features the many aspects of bone in the craniofacial region, including embryology, cell biology, and stem cell biology. Section 2 focuses on teeth-tooth development, dentin, enamel, cementum, and tooth regeneration. Section 3 discusses the interaction between bones and teeth, including those associated with inflammatory processes, periodontal ligaments, biomechanics, and other impact factors-such as nutrition, metabolic bone diseases and therapeutic modalities.The novel approach of linking the basic principles of the cell and molecular biology of hard tissues to clinical correlates will appeal to readers at all levels of their research careers, both students and faculty; faculty interested in a comprehensive text for reference; and  clinicians interested in the biologic aspects of bones and teeth.

    Contributors
    Preface
    Acknowledgments
    Foreword
    Bones of the oral-dental and craniofacial complex
    Embryology of craniofacial bones
    Clinical correlate: cleft lip and palate
    Cell and molecular biology of the osteoclast and bone resorption
    Clinical correlate: osteopetrosis
    Clinical correlate: CLCN7-associated autosomal recessive osteopetrosis
    Osteoblasts of craniofacial bone
    Clinical correlate: cleidocranial dysplasia
    Cell biology of craniofacial bone: osteocytes
    Clinical correlate: Van Buchem disease
    Stem cell biology in the craniofacial apparatus
    Clinical correlate: stem cell therapy for craniofacial bone regeneration
    Extracellular matrix and mineralization of craniofacial bone
    Clinical correlate: osteogenesis imperfecta
    Teeth
    Tooth development
    Clinical correlate: tooth agenesis
    Dentin
    Clinical correlate: dentinogenesis imperfecta, restorative procedures, and caries
    Enamel fabrication: the story of amelogenesis
    Clinical correlate: amelogenesis imperfecta
    Cementum
    Clinical correlate: case study of identical twins with cementum and periodontal defects resulting from odontohypophosphatasia
    Dental engineering: tooth regeneration
    Clinical correlate: periodontal regeneration
    Clinical correlate: natural tooth regeneration
    Clinical correlate: regenerative endodontics in an immature tooth with pulpal necrosis and periapical pathosis
    Bones and teeth
    Bone and tooth interface: periodontal ligament
    Clinical correlate: two cases of destructive periodontal disease
    Periodontal disease and infl ammationinduced bone remodeling
    Clinical correlate: endodontic lesions
    Biomechanics of teeth in bone: function, movement, and prosthetic rehabilitation
    Clinical correlate: biomechanics of teeth in bone
    Impact of metabolic bone disease on craniofacial bones and teeth
    Clinical correlate: renal osteodystrophy
    Mineral metabolism and its impact on craniofacial bones and teeth
    Clinical correlate: mineral metabolism and disruption of dentoalveolar development in a case of craniometaphyseal dysplasia (CMD)
    Sun, nutrition, and the mineralization of bones and teeth
    Clinical correlate: vitamin D deficiency
    Impact of therapeutic modalities on craniofacial bones and teeth
    Clinical correlate: osteoradionecrosis of the jaws (ORN)
    Index
    Figures from the book are available for download at www.wiley.com/go/mccauley

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